Clinical and Research Laboratories
Clinical Diagnostic Laboratories
The Knight Diagnostic Laboratories (KDL)
The KDL was formed in January 2011 by combining four individual laboratories: the Molecular Diagnostic Center, Clinical Cytogenetics, Biochemical Genetics and the Pathology Translational Research Lab. This single laboratory entity, with a focus on cutting-edge personalized diagnostics, leverages the decades of clinical laboratory and research experience within the individual labs with the sum being much more than the parts.
Research Service Laboratories
Research Cytogenetics Laboratory
The Research Cytogenetics Lab is a fee-for-service cytogentics laboratory available to genetics researchers to assist in development and execution of cytogenetics experiments for research purposes.
OHSU Gene Profiling Shared Resource
The OHSU Gene Profiling Shared Resource is a full-service genomics facility providing research scientists and clinicians with services for RNA expression profiling, DNA variation analysis, and nucleic acid extraction.
OHSU Massively Parallel Sequencing Shared Resource
The OHSU Massively Parallel Sequencing Shared Resource functions as a full service genomics facility serving research scientists and clinicians with a full range of applications based upon massively parallel sequencing protocols.
OHSU Elemental Analysis Core
The Elemental Analysis Core provides highly sensitive elemental quantification, including sample preparation, data analysis, and experimental guidance, through Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technology.We offer these services to the academic community and the public to facilitate research in a broad range of fields while encouraging new areas of inquiry and expanding public education and interest in this emerging field.
The Laboratory of Dr. Paul Spellman is interested in using genetic, genomic, and proteomic data to understand and model the biology of cancer and to develop methods to effectively deploy therapeutic agents in the age of molecularly guided medicine.
The Laboratory of Dr. H. Scott Stadler is focused on discerning the molecular functions of vertebrate Hox proteins in normal development and disease. The Hox proteins are an evolutionarily conserved group of helix turn helix transcription factors that exhibit remarkable conservation in sites of expression, chromosomal clustering, and loss of function phenotypes in both vertebrate and invertebrate species.