Molecular and Medical Genetics | Genome Science Seminar Series

The Genome Sciences Hub integrates basic science and clinical faculty across OHSU who work in disciplines of genetics and genomics, epigenetics, rare disease genetics, genome technologies and computational biology, stem cell and developmental biology, cancer genetics, and gene therapy. Faculty within the Hub apply multidisciplinary approaches, including single gene and single cell technologies, gene therapies, transcriptional pathway and whole genome analyses, and animal models of disease.

The interdisciplinary nature of this Hub is based on the combined basic science and clinical composition of the Department of Molecular & Medical Genetics that will cultivate interactions between the basic sciences and the clinical researchers and practitioners. The goals of the Genome Sciences Seminar Series are to facilitate interactions among faculty and trainees and to provide an opportunity to expand breadth and depth of knowledge in a variety of Genetic research areas that both complement and expand attendees areas of research focus. The Genome Sciences seminar will host 4 to 5 outside speakers for the benefit of the entire OHSU science community. We will also host OHSU faculty and trainees or students and postdoctoral fellows throughout the year. 

Time: Mondays, September through June 12-1pm
Streaming online via Webex
Email MMGoffice@ohsu.edu for links

September 27, 2021

Presented by: Abdenour Soufi, Ph.D

Seminar Title: "Mechanistic insights into controlling cell identity by transcription factors"

October 4,2021

Presented by: R. Stephen Lloyd, PhD

Seminar Title: "Drivers of hepatocellular carcinogenesis – roles of DNA repair and replication"

October 11, 2021

Presented by: John Brigande, PhD

Seminar Title: "Gene Therapy for Congenital Deafness"

October 18, 2021

No Molecular and Medical Genetics Genome Science Seminar 

October 25, 2021

Presented by: Dwight Koeberl, MD, PhD

Seminar Title: "AAV gene therapy for glycogen storage diseases"

November 1, 2021

Presented by: Oleg Varlamov, PhD

Seminar Title: "Maternal Diet Modulates Developmental Hematopoiesis in Rhesus Macaques"

November 8, 2021

Presented by: Eric Goetzman, PhD

Seminar Title: “Alternative medium-chain fatty acid therapies”

November 15, 2021

Presented by: Claudio Mello MD, PhD

Seminar Title: “Comparative genomics provides insights into lineage-specific features in birds”

November 22, 2021

No Molecular and Medical Genetics Genome Science Seminar  

November 29, 2021

Presented by: Mushui Dai, PhD

Seminar Title: "A novel SUMO ligase function of USP36 in ribosome biogenesis."

December 6, 2021

Presented by: Joshua Saldivar, PhD

Seminar Title: “Nuclear dynamics coordinating DNA replication and transcription”

December 13, 2021

No Molecular and Medical Genetics Genome Science Seminar 

December 20, 2021

No Molecular and Medical Genetics Genome Science Seminar 

December 27, 2021

No Molecular and Medical Genetics Genome Science Seminar 

January 3, 2022

No Molecular and Medical Genetics Genome Science Seminar 

January 10, 2022

Presented by: Daniel Liefwalker, PhD

Seminar Title: "Lipid biosynthesis is a metabolic liability in oncogene-driven hematopoietic malignancies"

January 17, 2022

No Molecular and Medical Genetics Genome Science Seminar 

January 24, 2022

Presented by: Marissa Co, PhD 

Seminar Title: “Shared and distinct functional effects of patient-specific Tbr1 mutations on cortical development"

January 31, 2022

Presented by: Ayumu Konno Ph.D.

Seminar Title: "Cell type-specific promoters in brain cells for AAV vectors" 

February 7, 2022

Presented by: Taisuke Furusho, PhD

Seminar Title: "AAV mediated gene therapy for kidney disease"

February 14, 2022

Presented by: Scott Kennedy 

Seminar Title: "Mysteries of Mitochondrial Mutagenesis"

February 21, 2022

No Molecular and Medical Genetics Genome Science Seminar 

February 28, 2022

No Molecular and Medical Genetics Genome Science Seminar 

March 7, 2022

No Molecular and Medical Genetics Genome Science Seminar 

March 14, 2022

Presented by: Gurkan Galip Yardimci 

Seminar Title: "Characterization of cell state via modeling of multi-omics data"

March 21, 2022

No Molecular and Medical Genetics Genome Science Seminar 

March 28, 2022

No Molecular and Medical Genetics Genome Science Seminar 

April 4, 2022

Presented by: Anne Vonada

Seminar Title: “Drug-Mediated Expansion of Gene-Edited Hepatocytes In Vivo”

April 11, 2022

No Molecular and Medical Genetics Genome Science Seminar 

April 18, 2022

Presented by: Eve Lowenstein

Seminar Title:  "Investigating nuclear organization in a Drosophila melanogaster human tauopathy model"

April 25, 2022

Presented by: Kevin MacPherson 

Seminar Title: "Single cell analysis of pancreatic ductal adenocarcinoma"

May 2, 2022

Presented by: Steve S Rich, PhD

Seminar Title: "From Bench to Bedside to Community in Type 1 Diabetes"

May 9, 2022

Presented by: Tiffany DeVine

Seminar Title: "LCHAD deficiency in an iPSC-derived Retinal Pigment Epithelium model"

May 16, 2022

Presented by: Zinab Doha

Seminar Title: "Modeling the heterogeneity and therapeutic response of Triple-negative breast cancer''

May 23, 2022

Presented by: Shannon Babcock

Seminar Title: "Studying Molecular Mechanisms of LCHADD Chorioretinopathy Using LCHADD Mouse Model"

May 30, 2022

No Molecular and Medical Genetics Genome Science Seminar 

June 6, 2022

Presented by: Michael Martinez

Seminar Title: "Methods to Enhance In Vivo Gene Editing for Treatment of Phenylketonuria"

June 13, 2022

No Molecular and Medical Genetics Genome Science Seminar 

October 5, 2020

Presented by: Thomas M. Vondriska, Ph.D. University of California

Seminar Title: "A chromatin structural model for complex cardiovascular disease"

October 12, 2020

Presented by: Gail Mandel, Ph.D., Senior Scientist, Vollum Institute

Seminar Title: "Rett syndrome: Insights from a rare disorder"

October 19, 2020

Presented by: Jonathan Brody, Ph.D. Director of Surgical Research

Seminar Title: "Can we target an element of pancreatic cancer cells’ pro-survival phenotype?"

October 26, 2020

Presented by: Nathalie Pamir, Ph.D., Depts. of Medicine & Biochemistry

Seminar Title:  "High density lipoprotein in cardiovascular disease and stroke among Whites and Blacks: The good cholesterol not so good in Blacks"

November 2, 2020

Presented by: Lea M. Starita, Ph.D. Research Assistant Professor, Genome Sciences, University of Washington

Seminar Title: "Getting to community surveillance for COVID-19"

November 9, 2020

Presented by: Ellen Langer, Ph.D., OHSU

Seminar Title: "A role for the prolyl isomerase PIN1 in fibroblast activation in pancreatic cancer"

November 16, 2020

Presented by: Allison Allen, M.D

Seminar Title: "cfDNA for Monogenic Disorders"

November 30, 2020

Presented by: Dr. Alejandro Lomniczi, Research Assistant Professor, Oregon National Primate Research Center

Seminar Title: "Epigenetic Writers, Readers and Erasers in the Control of Female Puberty"

December 7, 2020

Presented by: Cedric Feschotte, Ph.D. Professor, Department of Molecular Biology and Genetics, Cornell University

Seminar Title: "Fighting Fire with Fire: Endogenous Retroviruses Boost Human Immunity"

January 11, 2021

Presented by: Rita Cervera Juanes, Ph.D., OHSU

Seminar Title: "Investigating the neuroepigenome to identify targets for the treatment of alcohol use disorders"

January 25, 2021

Presented by: Adam Krieg, Ph.D., OHSU

Seminar Title: "Physiological Hypoxia As a Regulator of Ovarian Biology"

February 1, 2021

Presented by: Jared Fischer, Ph.D., OHSU

Seminar Title: "Nanomaterials for enhanced viral vector delivery and cancer detection"

February 8, 2021
February 22, 2021

Presented by: Megan Dennis, Ph.D., UC Davis

Seminar Title: "Using zebrafish to test neurodevelopmental genes important in human disease and evolution"

March 8, 2021

Presented by: Elaine A. Ostrander, Ph.D.

Seminar Title: “Four legs, fuzzy coat, a tail and a woof: How evolution got there”

March 15, 2021

Presented by: Casey Thornton, MMG Graduate Student, Andrew Adey Lab

Seminar Title: "Characterizing glial chromatin accessibility in the human cortex and hippocampus"

April 5, 2021

Presented by: Kevin Costello, Graduate Student, Beckman Research Institute at City of Hope

Seminar Title: "The role of Transposable elements in regulation and evolution"

April 26, 2021

Presented by: Eve Lowenstein, MMG Graduate Student Adey Lab

Seminar Title: "Effects of frontotemporal dementia associated Tau mutations on nuclear organization in a Drosophila melanogaster human tauopathy model"

May 3, 2021

Presented by: Sara Gosline, Ph.D., P.N.N.L.

Seminar Title: “Harnessing the power of ‘omics in rare disease: Lessons from building cohorts, model systems, and algorithms in Neurofibromatosis 1”

May 10, 2021

Presented by: Alejandro Aballay, Ph.D. Chair, Molecular Microbiology and Immunology, School of Medicine

Seminar Title:  "C. elegans as a model host to study the role of the neural-gut axis in immune response against bacterial pathogenetic disease models"

May 17, 2021

Presented by: Carsten Shultz, Ph.D., Chair, Chemical Physiology and Biochemistry, School of Medicine

Seminar Title: "Lessons learned from genetic disease models"

May 24, 2021

Presented by: Zinab Doha, MMG Graduate Student

Seminar Title: "Myc Regulation of The Therapeutic Responses in Triple-Negative Breast Cancer"

June 7, 2021

Presented by: Hisham Mohammed, Ph.D Assistant Professor, Medical and Molecular Genetics

Seminar Title: "Multi-omics single-cell approach reveals transcriptional and epigenetic plasticity in hormone driven cancers "