MMG encompasses numerous research faculty, clinicians, fellows, and students with diverse research interests surrounding molecular and medical genetics approaches to understanding the basis and treatment of human disease. Our research includes cancer genetics, molecular genetics, gene therapy technologies, molecular diagnostics, developmental genetics, medical genetics cytogenetics, quantitative trait genetics, biochemical genetics, cell biology and biochemistry. Several laboratories focus on "tumor suppressor" and "oncogene" pathways involved in a variety of common human cancers, with one goal being to capitalize on this knowledge for translational research purposes. One central theme in the program is the utilization of a variety of genetic, molecular and cellular approaches for analyzing normal and disease processes. Learn more
Fatty Acid Oxidation Disease Research
One of the complications of LCHAD deficiency is vision loss because of a degeneration of the retina, a part of the eye that is essential for us to see. This degeneration of the retina is called retinopathy and the cause of retinopathy in children with LCHAD is not known. Dr. Melanie Gillingham is currently conducting a study in cells to investigate the cause of LCHAD retinopathy. Help support Dr. Gillingham's research today!
Donations can also be made by check; please make check(s) payable to: OHSU Foundation
Account 25260 Genetics Research
P.O. Box 29017
Portland, OR 97296
In the News
Single cell imaging, technology development and creativity
Currently developing and deploying single-cell technologies to profile a variety of properties of the epigenome, the chemical compounds that modify the genome in ways that tell it what to do, where to do it and when to do it.
Congratulations to Mu-Shui Dai. Xiao-Xin Sun, Yanping Li, Timothy T. Carey, Catherine H. Feng, Hong-Ming Zhu
Very proud that their paper titled “The ubiquitin-specific protease USP36 associates with the microprocessor complex and regulates microRNA biogenesis by SUMOylating DGCR8” just came out in Cancer Research Communications.
Congratulations to Rosalie C. Sears, Mu-Shui Dai, Xiao-Xin Sun, Yingxiao Chen, Yanping Li, Roselyn S. Dai, Jonathan C. Savage, Ujwal Shinde, John Klimek, Larry L. David, Emma A. Young, Markus Hafner
Very proud that their paper titled “The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.” just came out in Nucleic Acids Res, 51:2023