Graduate Program Curriculum

Featured courses

Epigenetics (NEW!) | 3 credits

Course Directors: Lucia Carbone, Ph.D., Andrew Adey, Ph.D.

This course is focused on discussions involving both students and lecturers and covers topics such as: Waddington epigenetic landscape and cell fate, Epigenetics mechanisms: DNA methylation &histone modifications, Non-coding RNAs and epigenetics, X-inactivation and monoallelic expression, Chromatin structure and organization, Epigenetic inheritance: somatic, meiotic and trans-generational, Genomic imprinting, Epigenetic Reprogramming and Environmental epigenetics.

Eukaryotic Genetics | 3 credits

Course Director: Sue Richards, Ph.D.

Presentations by MMG Faculty with Student-led discussions surrounding the topics of: quantitative genetics, genetic linkage & association analysis, Mendelian/ complex inheritance, principles of cytogenetics, mouse and zebrafish model systems, CRISPR/Cas9 mediated genome engineering in model systems, cancer genetics, application of NGS early cancer detection, primate genomics, genomic medicine, developmental genetics, and epigenetics and immunogenetics.

Genetic Basis of Human Disease | 3 credits

Course Director: Sue Richards, Ph.D.

A team of faculty experts discusses topics including chromosomal basis of disease, cancer genetics, disorders of energy metabolism, amino acid disorders, blood coagulation disorders, congenital heart defects, disorders of extracellular matrix, platelet disorders, endocrine disorders and stem cell/gene therapy. Format is reading, journal club, and conference style.

Gene and Cell Therapy | 2 credits

Course Directors: Hiroyuki Nakai, M.D., Ph.D., Cary Harding, M.D.

The course presents an introductory overview of various gene delivery systems and cell-based approaches;advances in DNA/RNA/peptide delivery, cellular genome engineering and understanding the biology of cells as therapeutics;applications of gene delivery technologies and cell transplantation with a focus on translational research and current issues in gene and cell therapy and regenerative medicine. The course consists of lectures by experts in the relevant fields in a lecture/paper discussion format. Students will be required to write an NIH style research proposal on a relevant topic of their choice and expected to have an oral presentation during the course.

First year curriculum:

Second year curriculum:

Course Name Course Number Credits When
Eukaryotic Genetics MGEN 622 3 F
Journal Club MGEN 605/606 1 F, W, Sp
Departmental Seminar MGEN 607A 1 F, W, Sp
Departmental Grand Rounds MGEN 611 1 F, W, Sp
Genetic Basis of Disease MGEN 623 3 Sp

Common elective courses:

Course Name Course Number Credits When
Essentials of Molecular and Medical Genetics MGEN 610 2 W
Clinical Experience in Medical Genetics MGEN 609 2 TBA
Mechanisms of Cancer Journal Club MGEN 606 1 F, W, Sp
Molecular & Medical Genetics Journal Club MGEN 605E 1 F, W, Sp

All courses offered by MMG

For full list of offered courses, please see the MMG Student Handbook.

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