Maria Fleseriu M.D., F.A.C.E.

Photo of Maria Fleseriu, M.D., F.A.C.E.
Faculty profile
  • Professor and director OHSU NW Pituitary Center

Professor of Neurological Surgery School of Medicine

Accepting new patients

4.7 out of 5 (194 Ratings, 52 Comments)


  • Endocrinology and diabetes

Special focus on

  • Endocrinology


  • M.D., The University of Medicine and Pharmacy of Timisoara, Timisoara Romania 1993
  • Residency:

    • Internal medicine, University Hospital Sibiu, Romania
    • Case Western Reserve University, Internal Medicine
  • Fellowship:

    • Endocrinology, University Hospital Sibiu and National Institute of Endocrinology, Romania
    • Cleveland Clinic, Endocrinology, Diabetes and Metabolism
  • Certifications:

    • Board Certified in endocrinology


Dr. Fleseriu received her medical degree from The University of Medicine and Pharmacy of Timisoara, Romania and completed residency training in internal medicine and an endocrinology fellowship with a focus in pituitary disorders in Romania. Subsequently, she completed an additional internal medicine residency at Case Western Reserve University, Cleveland, Ohio and an endocrinology fellowship at Cleveland Clinic Foundation, Cleveland, Ohio.

Dr. Fleseriu has a long standing clinical and research interest in the pathophysiology and treatment of important clinical aspects of pituitary and adrenal disease. Her recent research is devoted to new treatments of pituitary tumors. She is active in international collaborative studies that include treatment with short and long acting novel multiligands somatostatin analogs, new chimeric molecules directed towards somatostatin and dopamine receptors as well as a new glucocorticoid receptor blocker.

She is a frequent guest speaker on various topics related to treatments of pituitary tumors, especially acromegaly and Cushing’s disease.

As the Director of the NW Pituitary Center at OHSU, Dr. Fleseriu champions a balanced approach to clinical management, combining the most recent advances in the field of neuroendocrinology and the aggressive pursuit of multidisciplinary research. She remains highly involved in teaching medical students, residents, and fellows as well as physician assistant students.

Dr. Fleseriu has published extensively and has coauthored several book chapters detailing pituitary and thyroid pathology.

She is a specialty chief editor for Frontiers in Endocrinology: Pituitary Endocrinology

Clinical interests:

She focuses her clinical practice on the diagnosis and treatment of pituitary and adrenal tumors and pituitary dysfunction, with a particular interest in growth hormone excess (acromegaly) and on cortisol excess (Cushing) and deficiency (adrenal insufficiency).

Acromegaly Cushing’s Disease Complex prolactinomas Neuroendocrine disorders Non-functioning pituitary tumors Adrenal disorders

Clinical trials

Dr. Fleseriu is a Professor of medicine/endocrinology and neurological surgery and has served as director of the NW Pituitary Center at Oregon Health & Science University, Portland, OR since 2007. She is a member of  the Editorial Boards for Pituitary and Faculty of 1000-Neuroendocrinology and is an ad hoc reviewer for numerous other journals. She is a member of the Endocrine Society Clinical Guidelines Committee and the American Association of Clinical Endocrinologists Continuing Medical Education Committee.

Visit the Department of Neurological Surgery's website for information about academics, conferences, residency and fellowships.

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  • English

Patient Ratings

4.7 out of 5 (194 Ratings, 52 Comments)

The patient ratings score is an average of all responses to the question "How likely would you be to recommend this provider to your family and friends (on a scale of 0 to 10)" on our nationally-recognized NRC patient surveys.

Patient Comments

  • Feb 17, 2019

    Dr. Fleseriu listened and had feedback to all of my concerns and address all my concerns individually completely. She was very thorough and I look forward to continuing seen her in the future. I hope that she could help me with my health.

  • Feb 16, 2019

    She and her team were kind, listened, and I did not feel rushed.

  • Jan 27, 2019

    My doctor is extremely knowledgeable and kind.

  • Jan 24, 2019

    She was very thorough explaining my current situation.

  • Jan 24, 2019

    Dr. Fleseriu has consistently proven to be extremely knowledgeable, informative and compassionate in her conduct.

  • Jan 12, 2019

    I was not given any advanced notice of any of the procedures to be done the day I went in. the middle of it all, three interns jumped in. I had no idea who they were, what they represented, and they spoke so fast, I could barely understand them. I resented it and I will not be seeking any further medical attention from OHSU.

  • Jan 10, 2019

    I feel that I am truly receiving the very best care for my health with Dr. Fleseriu. I know that she stays on top of the very latest science in her field and has a wonderful bedside manner with her patients, knowing each of them personally. She also takes care in selection of her clinic team to surround herself with other caring professionals.

  • Dec 29, 2018

    Dr. Fleseriu is personable, easy to talk to, a good listener, knowledgeable and trustworthy. She always answers all my questions and concerns and I feel she has my best interest at heart with every visit. I?m grateful to have her as my doctor.

  • Dec 29, 2018

    Dr Fleseriu, is thorough, knowledgeable and has a great bedside manner. I highly recommend her!

  • Dec 29, 2018

    I have been a patient for the past 3 years and always feel that when I go for my visit with Dr. Fleseriu that I get good attention and good information and she takes all the time I need to answer all my questions and determine what kind of treatment or follow up I need.

  • Dec 20, 2018

    I have never been to OHSU that the staff has NOT been awesome in every way, professional, courteous and polite. Everyone is also so helpful! THANK YOU!

  • Nov 21, 2018

    She is great! Very attentive and informative.

  • Nov 16, 2018

    Dr. Fleseriu's been great. She's been helping me get better after the brain tumor was removed, and she's still working with me to continue getting better. So, no, she's been great and I'm really glad that I have her as my doctor.

  • Nov 15, 2018

    She was very knowledgeable and helpful concerning my illness. The staff was also excellent.

  • Nov 08, 2018

    Maria is awesome she makes every appointment easy. We travel a long way she always has everything she needs done ready for us.

  • Nov 05, 2018

    Dr. Fleseriu is very knowledgeable, very passionate, and very interested in the pituitary gland and those that suffer from tumors on it. Sometimes... I got the impression that she was pre-destined to evaluate what I may or may not have said, but... and was certainly abrupt occasionally, but for the most part she was approachable, knowledgeable, concerned and responsive. Overall, I thought the experience rated an 8.

  • Sep 22, 2018

    I was very impressed with Dr. Fleseriu. She is more knowledgeable about my specific medical condition than any other doctor I have encountered. Within a short amount of time, she had educated me on several different areas of my pituitary disorders - more than I have learned over the previous 20 years. I quickly developed trust with her, seeing how well she knows pituitary conditions. She was armed with a plan of action right away, the key word being "action." There was none of the same old "we are doing all we can, there is little we know, just deal with it," etc. I think the most important thing is that Dr. Fleseriu provided me with hope, which I had lost a long time ago. I look forward to my new treatment with Dr. Fleseriu. I feel like I am finally in capable hands!

  • Sep 13, 2018

    This was a follow-up appointment with Dr. Fleseriu. In all of my previous encounters, either as the patient or accompanying the patient, Dr. Fleseriu has proven to be very knowledgeable and informative while also demonstrating genuine interest and concern for myself and other family members who either accompanied me or I accompanied.

  • Sep 06, 2018

    Doctor was very courteous and helpful

  • Sep 01, 2018

    Maria Fleseriu was very helpful in helping obtain second opinion regarding pituitary tumor.

  • Aug 17, 2018

    Maria cares!

  • Aug 15, 2018

    I felt my time with her was too limiting. Sent in her assistant, he did everything and just kind of pushed me through at the tail end with her.

  • Aug 15, 2018

    responsive, organized, and informed

  • Aug 15, 2018

    Great the doctor came in on time and answered all of my questions.

  • Aug 04, 2018

    Very frustrating. She makes comments and sometimes will explain her self....others she will not. We don?t have a great patient doctor relationship.

  • Aug 03, 2018

    As usual my experience was fantastic. Everyone was professional and compassionate. I always feel like the doctors take time to answer my questions and are not in a rush to leave.

  • Aug 02, 2018

    Dr. Fleseriu has been my endocrinologist for several years and is very knowledgeable and caring

  • Jul 23, 2018

    Dr Fleseriu is a great provider and is very knowledgeable in her field. I?m very confident in her support of my care.

  • Jul 19, 2018

    she's a wonderful doctor. I ? I don't think I could be here if she wasn't here because she has saved, literally, saved my life, and I'll listen to anything she says, and follow her to the bus stop. Thank you.

  • Jul 19, 2018

    She is very pleasant, very, very informative, and definitely cares about her patients. I appreciate her very much.

  • Jul 18, 2018

    Dr. Fleseriu is caring, knowledgeable and trustworthy.

  • Jul 18, 2018

    Dr Flesirue is amazing! I completely trust her comprehensive care of my rare conditions. I recently moved to the East Coast and I commute to continue under her care!

  • Jul 12, 2018

    I feel very comfortable, I've seen Doctor Fleseriu, very knowledgeable, put me at ease, explains everything that's going on in my body and things that are going to be happening in the future. She's wonderful, smart, intelligent, kind, and informative.

  • Jul 10, 2018

    Very good.

  • Jun 21, 2018

    Each interaction I have had with Dr. Fleseriu has consistently proven her strong desire to be thorough in diagnosing and prescribing a treatment care plan, educational about the condition and various treatments, and instructive about what to expect from the treatment care plan or condition.

  • Jun 17, 2018

    The information about my disease and possible cures was excellent. I just wish it could have been done sooner, in a more timely fashion, like tests not taken a month apart, etc..

  • May 25, 2018

    Not only did Dr. Fleseriu answer my questions, she also answered the questions my mother (who accompanied me to my appointment and has the same condition as me) posed.

  • May 12, 2018

    The doctor went on an extensive rant about naturopaths and naturopathic supplements. Basically, she said that she didn't believe in naturopathic medicine and that all supplements were useless and/or dangerous. I agree that many of the supplements available at places like Walmart are of poor quality. However, naturopathic supplements that are verified by a third party have the same, or better, quality as pharmaceutical products. Her attitude and behavior was unprofessional. Also, the record of the appointment indicated that she wanted me to change the way I take warfarin. She didn't say anything about this during the appointment, and she certainly is not in a position to dictate a change in a critical, well managed medication. I don't have the expertise to judge her competency in her specialty, but she didn't inspire a lot of confidence.

  • May 04, 2018

    She is good at explaining things about my health, but at times she talks too fast for things to soak inn for me.

  • Apr 30, 2018

    great provider , timliness is poor, didnt feel like she was thourough on our plan but it was my first appointment. wait till next time to see

  • Apr 03, 2018

    The doctor was very good at explaining what needs to happen next, but the next part hasn't been scheduled yet because I haven't received the call I have been expecting for the last week.

  • Mar 06, 2018

    Nurse Sam and Dr Fless Dog are my healthcare Heros. Nurse Sam courageously battles the evil insurance companies to make sure I have the healthcare I need to live. I am thank full for them. All I am trying to do is get the pesky tumors out of my brain so I can live and let my daughter see me get old and play with her. Dr Fless Dog and Nurse Sam help make sure that happens. I appreciate them so much. I don't like the insurance company who is actively trying to kill me and prevent my curing. Nurse Sam battles them with fists of fury! When they come at her she is like "Come at me bro" And punches them in the throat. When they don't subside or get all pissy, Dr Fless Dog steps in, shoulder checks the fools and they bow down to her neurological authoritay. She makes them pee sitting down. Respectfully, [Name]

  • Feb 26, 2018

    I feel Dr. Fleseriu has given me outstanding care. She is an expert in the disorders I am seeing her for and she is very caring about my health. She is arranging for me to see doctors for other issues caused by my disorders. I have referred others to her for the same disorders I have because she is so knowledgable and caring. Easy to communicate with her office via MyChart.

  • Feb 15, 2018

    No complaints

  • Feb 11, 2018

    I feel Dr. Fleseriu is one of the best Endo's out there, but she needs to slow down a little bit & not talk over people's heads. A lot of Cushing's patients have memory/cognitive issues, so it's difficult to make sense of what she's talking about as she not only talks really fast, but tends to talk in complicated medical terms. Also she can sometimes make people feel bad for decisions they have made, so it's easy to be defensive when speaking with her. Overall im pleased with her care.

  • Feb 06, 2018

    I am very pleased with my Drs..

  • Jan 16, 2018

    I was referred to my provider by a family member and have already referred her to someone

  • Jan 09, 2018

    Dr. Fleseriu is very kind and explains her plan in details and is happy to answer questions. She does not seem in a hurry and it is always a pleasant experience. There is never a wait time in her office.

  • Jan 03, 2018

    She rattled on in medical jargon as though I were a third-year medical student. If I had not researched our topic before-hand I would not have been able to follow her at all. She did not provide any educational benefit at all. She seemed to just want to get through with the exam and do something else. Was cavalier about what I might have to go through.

  • Dec 20, 2017

    Dr. Maria Fleseriu is amazing! I have visiting many endocrinologists in my lifetime from coast to coast and she is by far the best! It is no exaggeration that she has changed my life. I am in my best care in her hands and I am confident that she cares for and respects me as a person. She is a gem and OHSU is lucky to have her.

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