Graduate Training in Translational Science and Cardiovascular Research

Graduate training in translational science and cardiovascular research

Sponsored by: A Ruth L. Kirschtein NRSA Training Grant (T-32) Award from the National Institutes of Health, Bethesda MD.

Principal Investigator: Nabil Alkayed, M.D., Ph.D., OHSU Knight Cardiovascular Institute.

Program overview

The NIH-sponsored training program for Translational Science and Cardiovascular Research at the OHSU Knight Cardiovascular Institute is dedicated to the advanced specialty research training of physician-scientists and basic scientists. The program funds a total of six positions (M.D., D.O., or Ph.D.) for a two-year research experience in translational cardiovascular research (see faculty).

The aim of the program is to provide laboratory research training and mentoring that will establish the basis for a successful career as an independent investigator in an academic institution. Laboratory research will be supplemented with course work and scientific seminars. Unique aspects of the program include provision of individualized curriculum and career development, and the team-approach to mentoring that include both basic and clinical scientists. Our goal is to produce scientists with a broad outlook and a focus on bringing science to the benefit of patients.

Program components

The duration of financial support for this program is two years. For physician-scientists, up to one year of the research program can qualify towards an ACGME-accredited Cardiology Fellowship.

The training program will involve the following activities:

  • Research training under the guidance of a primary research mentor
  • Periodic meeting with a mentoring team including the primary mentor, and two co-mentors
  • Course work (Biostatistics, Ethics of Research, Becoming a Successful Scientist, The Scientific Basis of Cardiology, Genetic Foundations of Cardiac Biology, Scientific Writing, etc.) or courses in the NIH-funded Human Investigation Certificate Program
  • Career counseling with the mentoring team
  • Participation in conferences (Cardiology Research Conference, Integrative Physiology, Annual Scientific Retreat)
An SEM image of the endothelium of a normal aorta (picture from Dr. Lindner's lab)
An SEM image of the endothelium of a normal aorta (picture from Dr. Lindner's lab)

Faculty and administration

Program director: Nabil Alkayed, M.D., Ph.D.
Associate director: Sanjiv Kaul, M.D.

Diabetes / vascular physiology / inflammation

Nabil Alkayed, M.D., Ph.D. | Virginia Brooks, Ph.D. | Sergio Fazio, M.D., Ph.D. | Antonio Frias, M.D. | Sanjiv Kaul, M.D. | Jonathan Lindner, M.D. | Daniel Marks, M.D., Ph.D. | Dawn Peters, Ph.D. | Jonathan Purnell, M.D. | Charles Roberts, Ph.D.

Developmental cardiology and programming

Craig Broberg, M.D. | George Giraud, M.D., Ph.D. | Lowell Davis, M.D. | Monica Hinds, Ph.D. | Sonnet Jonker, Ph.D. | Cynthia Morris, Ph.D. |Sandra Rugonyi, Ph.D. | David Sahn, M.D. | Kent Thornburg, Ph.D.

Regulatory and cellular physiology

Michael Andresen, Ph.D. | David Ellison, M.D. | Allison Fryer, Ph.D. | Eric Gouaux, Ph.D. | Beth Habecker, Ph.D. | Cheryl Maslen, Ph.D. | William Skach, Ph.D. | Mary Stenzel-Poore, Ph.D. | Philip Stork, M,D. | Zhengfeng Zhou, Ph.D.

Trainee requirements

  • Trainees must have a graduate degree (M.D., D.O., Ph.D., D.V.M., Pharm.D., D.D.S., etc.).
  • Trainees must either be a United States citizen, a non-citizen national of the United States, or have permanent resident status (possess a currently valid alien registration receipt card I-551, or other legal verification of such status).
  • Three trainees will be accepted per year.
Contrast enhanced ultrasound targeted imaging developed and refined by OHSU scientists provides a potent research method for the study of physiology.
Contrast enhanced ultrasound targeted imaging developed and refined by OHSU scientists provides a potent research method for the study of physiology.

Application process

The deadline for applications is December 15, 2017. Late applications may be considered if space is available.

Applications should include the following components:

  • Curriculum vitae
  • Personal statement that describes research and career goals
  • Research plan (5 pages maximum not including references)
  • Letter from proposed research mentor that includes mentoring plan and resources
  • Two additional letters of recommendation
  • Medical school or graduate school transcript (for external candidates only)

Please send completed applications by email to

Selection process

Applications will be judged based on evidence of interest in research, research aptitude, desire to pursue an academic career, interest in translational research and general fit for the research program.

External candidates with a high likelihood for entrance into the program will be asked to interview at OHSU.