Resident Research

Radiation Medicine Resident Research collage

Our program has a broad and flexible research focus that includes health services and outcomes-based research, clinical and translational research, as well as basic science research opportunities within OHSU community. Our goal is to provide an opportunity to garner a meaningful research experience during the critical years of residency training. 

Residents are encouraged to concurrently enroll into the Human Investigations Program (HIP), a training component within the institutional CTSA, also known as the Oregon Clinical and Translational Research InstituteEnroll in the Masters of Clinical Research Track or the Certificate Track. The residency is structured so concurrent participating in research activities are conducted such that all ACGME and ABR requirements are met. The length of the training program is not altered with research endeavors.

Our 2019-2020 resident research projects:

Mentor

Jerry Jaboin, M.D., Ph.D.

Research focus

Pediatric Cancer and Brain Cancer

Current research

My current pediatric projects focus on developing ways to improve care delivery for pediatric patients receiving radiotherapy. I also have projects investigating stereotactic radiosurgery outcomes with attention to combined modality treatments such as targeted and immunotherapies.

Current publications

Concurrent Radiosurgery and Immune Checkpoint Inhibition: Improving Regional Intracranial Control for Patients With Metastatic Melanoma. Murphy B, Walker J, Bassale S, Monaco D, Jaboin J, Ciporen J, Taylor M, Dai Kubicky C. Am J Clin Oncol. 2019 Mar;42(3):253-257. doi: 10.1097/COC.0000000000000509.

Prophylactic Aortic Stent Prevents Massive Hemorrhage and Hematemesis After Definitive Esophageal Chemoradiation in a Patient With Pretreatment Aortic Involvement. Murphy B, Azarbal A, Schenning RC, Bensch K, Sukumar M, Stelzer K, Nabavizadeh N. Pract Radiat Oncol. 2019 Sep - Oct;9(5):e447-e451. doi: 10.1016/j.prro.2019.05.008.

Complete list of Dr. Murphy's publications.

Mentor

Marka Crittenden, M.D., Ph.D.

Research focus

Immune response to radiation therapy, cancer, blood coagulation

Current research

My research focuses on the regulation of adaptive immune responses myeloid cells that infiltrate tumors following radiation therapy. I am specifically interested in how components of blood coagulation and anticoagulants influence the myeloid and adaptive immune responses following radiation.

Current publications

Role of the immunosuppressive microenvironment in immunotherapy. Tormoen GW, Crittenden MR, Gough MJ. Adv Radiat Oncol. 2018 Oct 23;3(4):520-526. doi: 10.1016/j.adro.2018.08.018. eCollection 2018 Oct-Dec. Review.

A Temporal Examination of Platelet Counts as a Predictor of Prognosis in Lung, Prostate, and Colon Cancer Patients. Sylman JL, Boyce HB, Mitrugno A, Tormoen GW, Thomas IC, Wagner TH, Lee JS, Leppert JT, McCarty OJT, Mallick P. Sci Rep. 2018 Apr 26;8(1):6564. doi: 10.1038/s41598-018-25019-1.

The Predictive Value of Inflammation-Related Peripheral Blood Measurements in Cancer Staging and Prognosis. Sylman JL, Mitrugno A, Atallah M, Tormoen GW, Shatzel JJ, Tassi Yunga S, Wagner TH, Leppert JT, Mallick P, McCarty OJT. Front Oncol. 2018 Mar 21;8:78. doi: 10.3389/fonc.2018.00078. eCollection 2018. Review.

Complete list of Dr. Tormoen's publications.

Mentor

Nima Nabavizadeh, M.D. and Reid Thompson, M.D., Ph.D.

Research focus

Clinical and Imaging Informatics

Current research

My research focuses on the application of clinical and imaging informatics (radiomics) to improve prediction of treatment response and radiation toxicities. Also, potential applications of artificial intelligence in the radiation oncology clinical workflow. Current projects include evaluation of auto segmentation algorithms of genitourinary structures and reviewing institutional outcomes following radiotherapy in the pediatric population.

Current publications

Artificial Intelligence in Radiation Oncology. Deig CR, Kanwar A, Thompson RF. Hematol Oncol Clin North Am. 2019 Dec;33(6):1095-1104. doi: 10.1016/j.hoc.2019.08.003. Epub 2019 Sep 11. Review.

Outcomes of carotid-sparing IMRT for T1 glottic cancer: Comparison with conventional radiation. Mohamed ASR, Smith BD, Smith JB, Sevak P, Malek JS, Kanwar A, Browne T, Gunn GB, Garden AS, Frank SJ, Morrison WH, Phan J, Zafereo M, Skinner H, Lai SY, Hutcheson KA, Lewin JS, Hessel AE, Thekdi AA, Weber RS, Fuller CD, Rosenthal DI. Laryngoscope. 2019 Feb 12. doi: 10.1002/lary.27873.

Imaging-Genomic Study of Head and Neck Squamous Cell Carcinoma: Associations Between Radiomic Phenotypes and Genomic Mechanisms via Integration of The Cancer Genome Atlas and The Cancer Imaging Archive. Zhu Y, Mohamed ASR, Lai SY, Yang S, Kanwar A, Wei L, Kamal M, Sengupta S, Elhalawani H, Skinner H, Mackin DS, Shiao J, Messer J, Wong A, Ding Y, Zhang L, Court L, Ji Y, Fuller CD. JCO Clin Cancer Inform. 2019 Feb;3:1-9. doi: 10.1200/CCI.18.00073.

Complete list of Dr. Kanwar's publications.

Mentor

Nima Nabavizadeh, M.D.

Research focus

Exploring the role of cell free DNA as a biomarker to detect and monitor malignancies. Also, refining our understanding of SBRT as a tool to treat early stage non-small cell lung cancer and hepatocellular carcinoma.

Current research

Prospectively comparing outcomes using SBRT and Y-90 for definitive treatment of HCC, using cfDNA as a biomarker in colorectal, early stage NSCLC, and esophageal cancers, and reviewing outcomes following neoadjuvant chemoRT in borderline resectable and resectable pancreatic cancer. 

Current publiations

Artificial Intelligence in Radiation Oncology. Deig CR, Kanwar A, Thompson RF. Hematol Oncol Clin North Am. 2019 Dec;33(6):1095-1104. doi: 10.1016/j.hoc.2019.08.003. Epub 2019 Sep 11. Review.

Predictors of Nodal and Metastatic Failure in Early Stage Non-small-cell Lung Cancer After Stereotactic Body Radiation Therapy. Cerra-Franco A, Liu S, Azar M, Shiue K, Freije S, Hinton J, Deig CR, Edwards D, Estabrook NC 3rd, Ellsworth SG, Huang K, Diab K, Langer MP, Zellars R, Kong FM, Wan J, Lautenschlaeger T. Clin Lung Cancer. 2019 May;20(3):186-193.e3. doi: 10.1016/j.cllc.2018.12.016. Epub 2018 Dec 29.

Histology, Tumor Volume, and Radiation Dose Predict Outcomes in NSCLC Patients After Stereotactic Ablative Radiotherapy. Shiue K, Cerra-Franco A, Shapiro R, Estabrook N, Mannina EM, Deig CR, Althouse S, Liu S, Wan J, Zang Y, Agrawal N, Ioannides P, Liu Y, Zhang C, DesRosiers C, Bartlett G, Ewing M, Langer MP, Watson G, Zellars R, Kong FM, Lautenschlaeger T. J Thorac Oncol. 2018 Oct;13(10):1549-1559. doi: 10.1016/j.jtho.2018.06.007. Epub 2018 Jun 27.

Complete list of Dr. Deig's publications.  

Mentor

Research focus

Current research

Mentor

Research focus

Current research

Incoming Residents

Resident Research News

March 1, 2020

Hans Kim, M.D. attended the 2020 Multidisciplinary Head and Neck Cancers Symposium in Scottsdale, AZ. The symposium provides case-based educational sessions that cover new multidisciplinary therapies, imaging, immunotherapy, treatment guidelines and supportive care in head and neck cancer. Dr. Kim presented his poster Baroreceptor Reflex Failure after Curative Chemoradiation for Oropharyngeal Cancer: A Potential Use of an Established Therapy.

Tormoen Grand Rounds-Jan 2020

Garth Tormoen, M.D., Ph.D., Chief Resident, presented his lecture Beyond local control, harnessing the immune response after radiation to improve cancer control  at the University of Washington's Radiation Oncology Grand Rounds on January 22, 2020.

December 1, 2019

Chris Deig, M.D. and Aasheesh Kanwar, M.D., PGY-3 residents co-authored and published Artificial Intelligence in Radiation Oncology.