CRISP Current Studies

Introduction:  This research study is done on patients who are being admitted to the hospital from the emergency department with heart failure. The purpose of this study is to learn about how ultrasound imaging can be used to assess your heart, lungs, and fluid status while admitted to the hospital. Doctors at OHSU want to learn whether ultrasound imaging can aid in a physician’s assessment and treatment of patients with heart failure.

Sponsor: The OHSU Emergency Department has been a part of the EMERGEncy ID NET Team since 1995.  This is a CDC grant funded network and in the last 20 years it has studied a wide range of emerging infectious diseases. The network has been a model for the creation of multi-center, emergency department and clinical syndrome-based research networks. Study activities and related publications have been directly translated into new treatment guidelines and practices that can prevent the occurrence and improve the management of acute infections in U.S. communities.  The research and surveillance network addresses the threat of emerging infectious diseases by assessing disease prevalence, risk factors, and management practices for acute presentations from the community among a diverse population presenting to emergency departments. It is comprised of 11 high-volume, geographically-diverse, and academically-affiliated emergency departments in the United States, which includes EMERGEncy ID NET hospitals serve a medically underserved population, including the indigent, the homeless, recent immigrants, and minorities, often underrepresented in other surveillance networks.

Introduction:  EMERGEncy ID NET’s most recent investigations include studying the emerging antibiotic resistance of Enterobacteriaceae causing urinary tract infections. Doctors at OHSU and across the nation are doing a study looking at the prevalence of antibiotic resistant bacteria in urinary tract infections. The purpose of this study is to determine the prevalence of antimicrobial resistance and risk factors among adults with UTI requiring hospital admission, as well as the effectiveness of current treatment protocols.

Introduction: This research study is done in children who are being admitted to the emergency department with dehydration. The purpose of this study is to learn about a new device that can be used to assess hydration status in children. Doctors at OHSU want to learn whether this device can aid in detecting dehydration at home. If patients are willing, we will do a test to look at blood flow in the patient’s finger that is not painful and will take less than 2 minutes. There is ZERO cost to participate.

Introduction: The purpose of the study is to test a new home device that monitors signs that the body produces to try and identify acute episodes of worsening mental health before they happen to prevent future ED visits. It is a wrist worn watch-like device that the patient will wear continuously for 7 days and will also fill out a few study questionnaires. The patient receives a $50 gift card as a thank you for their time to not only help improve future care but also that of other patients.

Introduction:  Researchers at OHSU are conducting a study about how adolescents manage pain. The purpose of this study is to help investigators learn more about pain and pain treatment in adolescents. You may be eligible for this research study because you are between the ages of 14-18 and have presented to the ED with an acute pain injury. If you are interested, we will pass along your contact information to the OHSU study team, and a member of the study team will reach out to determine eligibility for enrollment. Any information they collect will be kept confidential.

Introduction: Researchers at OHSU are conducting a study to learn more about the relationship between marijuana and other substance use and car accidents. You or your family member may have been invited to be in this research study because you drove a car in the 8 hours before you arrived in the Emergency Department. The information collected is completely confidential and may one day help us keep people safer and save lives. This study is funded by the Insurance Institute for Highway Safety. About 3,280 voluntary participants will be enrolled in the study.

Introduction: This research study aims to test the effectiveness of an assay to aid in diagnosing Heart Failure in patients that arrive in the Emergency Department with symptoms such as shortness of breath or swelling of extremities. The patients are screened based on their symptoms and age (22 years of age and older). As part of the study, participants are asked to provide one blood sample collection for testing the PBNP assay. The study is sponsored by Siemens Healthcare Diagnostics.

Introduction:  The purpose of the TEMPO study is to examine how pain changes over time in adolescents with a new pain problem. You may be eligible for this research study if you are between the ages of 11-17 and have presented to the ED with a new musculoskeletal injury or pain problem. If you are interested, we will pass along your contact information to the OHSU study team, and a member of the study team will reach out to determine eligibility for enrollment. Any information they collect will be kept confidential.