Oregon Health & Science University offers an ACGME-accredited one-year fellowship in Molecular Genetic Pathology, a subspecialty jointly accredited by the American Board of Pathology and the American Board of Medical Genetics.
The MGP fellow will gain a working knowledge of all current clinical and translational research molecular diagnostic procedures including DNA and RNA extraction, Southern blots, in situ hybridization/FISH, comparative genomic hybridization, mutation scanning methods, qualitative and quantitative amplification methods, gene-specific DNA sequencing, and high-throughput next generation (massively parallel) DNA sequencing. These technologies are applied in a wide spectrum of clinical settings including cancer, infectious disease, inherited disease (Mendelian, trinucleotide repeats, and complex), HLA-typing and identification.
The MGP fellow will learn to analyze and interpret molecular data from clinical cases, and to compose and communicate diagnostic reports. These molecular results will be correlated with clinical, laboratory, morphologic, immunophenotypic and cytogenetic findings.
Exposure to ethical issues, lab quality assurance and lab administration are an additional part of the MGP curriculum. The MGP fellow will also learn to design and implement translational research projects aimed at understanding the molecular basis of disease or translating such basic discoveries into improved patient care.
An optional second year of full time research may be available to interested and eligible fellows.
Candidates must have an MD degree (or equivalent), and have either completed training in an ACGME-accredited residency in Medical Genetics or Pathology (AP and/or CP). Applicants must be legally able to work in the U.S., or eligible to obtain work authorization, and are expected to take and pass the ABP molecular genetic pathology examination upon graduation.