People
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- Robert L. Eil, M.D.
- Associate Professor of Surgery
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Appointments and titles
- Associate Professor of Surgery, Division of Surgical Oncology, School of Medicine
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Areas of interest
- Cholangiocarcinoma
- Colorectal Liver Metastasis
- Tumor induced immune suppression
- T cell ion transport
- T cell engineering
- Translational science
- Investigator initiated clinical trials
Biography
Dr. Eil is an Assistant Professor of Surgery and Cellular, Developmental, & Cancer Biology at Oregon Health & Science University School of Medicine (OHSU). He is a surgeon-scientist focusing on applying immunotherapies to cancers involving the pancreas and liver. In the midst of his surgery residency at OHSU, Dr. Eil pursued a research fellowship at the Surgery Branch of the National Cancer Institute (NCI), gaining expertise in T-cell biology, tumor immunology, genetic engineering and cell transfer therapies.
During his time at the NCI, Dr. Eil identified unrecognized derangements within the tumor microenvironment that contribute to suppression of T-cell function and developed therapeutic approaches to restore T cell function based on these findings. All cancer immunotherapies rely upon the activity of T-cells.
Following completion of his clinical fellowship in surgical oncology at Memorial Sloan Kettering Cancer Center, Dr. Eil was recruited back to OHSU to establish his research group. Here, he will continue to investigate the immune microenvironment and engineering T-cells to function within the context of cancers involving the liver and pancreas. His multidisciplinary expertise provides a unique perspective to reinvigorate T-cell function, ultimately improving the lives and outcomes of patients suffering from this disease.
Eil lab
Jessica Briones
Graduate Student
Jessica is a Filipina-American scientist passionate about advancing immunotherapy for solid tumor cancers. After earning a Bachelor’s degree in Biological Sciences from UC Davis, she immersed herself in CAR T cell research and pursued a Master’s degree under the mentorship of Dr. Wendell Lim. By leveraging synNotch receptors, she improved the ability of CAR T cells to precisely target brain tumors and avoid off-target toxicity. Eager to learn more about translational research, Jessica transitioned into industry and joined Lyell Immunopharma as a Senior Research Associate. There, she helped develop the Stim-R technology to enhance the function and persistence of CAR T cell products. Now, Jessica is a PhD student in the PBMS program and is thrilled to continue immune-tumor research under the guidance of Dr. Robert Eil. Outside of the lab, you can find Jessica at the bouldering gym or at a local coffee roaster.
Olivia Huber
Graduate Student
Education: Suffolk University, Boston, MA (2018).
Post graduation, she worked at two biotech companies focusing on drug development in immunotherapies. Olivia is a student in the PBMS program and her current research focus is utilizing CAR T cells to target solid tumors. Beyond the lab, she loves to cook, run, hike, and find any excuse to spend time outside.
Matthew McWhorter
Research Assistant
Education: B.A. Biochemistry and Biophysics, Oregon State University (2022)
Matthew joined the Eil Lab in 2022 manages our murine colony and pursues various projects within the lab, including ionic control of T-cells and CAR T-cell adoptive transfer models for solid tumors.
Alex Bartlett, PhD
Camille Collier, BA
Chelsea Jenkins, PhD