The Vollum Institute at OHSU (OHSU/Kristyna Wentz-Graff)The Vollum Institute is a privately endowed research institute at Oregon Health & Science University dedicated to basic research that will lead to new treatments for neurological and psychiatric diseases. Vollum scientists have broad-ranging interests that coalesce around molecular neurobiology and cellular physiology. Their work has transformed the field of neuroscience and, in particular, have provided important advances in the study of synaptic transmission, neuronal development, neurotransmitter transporters, ion channels and the neurobiology of disease.
Learn more about the Vollum's mission

OHSU Neuroscience Post-Baccalaureate Initiative

The Vollum Institute is proud to support the new Neuroscience Post-Baccalaureate Initiative at OHSU and would like to welcome the first cohort of 2018 scholars — Rachel De La Torre, Braim Luciano Vazquez and Katherine Thanyamongkhonsawa.
Learn more about the Post-Bacc Initiative on the OHSU Research News blog

Wyatt named new director of diversity in research

Photo of Letisha Wyatt, Ph.D., director of diversity in research at OHSUMembers of the Vollum Institute congratulate Letisha Wyatt, Ph.D., on her recent appointment as director of diversity in research. Dr. Wyatt will lead the new OHSU Neuroscience Postbaccalaureate Initiative — a collaborative effort between the Vollum Institute, the Department of Behavioral Neuroscience and the Office of the Senior Vice President for Research — which provides neuroscience research opportunities for recent undergraduates from underrepresented backgrounds.
Read the full announcement in OHSU Research News

Vollum researchers in the news

FOXG1 Syndrome: Research with a personal connection

Photo of Soo-Kyung Lee, Ph.D.FOXG1 syndrome (FS), a rare neurodevelopmental disorder, is caused by inactivating mutations in FOXG1 gene. Researchers in Soo Lee's lab initiated a major effort to understand the molecular basis of FS in a hope to find treatment for this devastating disorder. The results of their study, published online in the journal Neuron, shed light on the etiology of FOXG1 syndrome and reveal a novel gene regulatory pathway that specifies neuronal characteristics during cerebral cortex development.

Soo Lee, Ph.D., is a professor of pediatrics in the Papé Family Pediatric Research Institute at OHSU Doernbecher Children's Hospital; she holds a joint appointment in the Vollum Institute.

Read the PubMed abstract
Learn more about Dr. Lee's personal connection to FOXG1 Syndrome at OHSU News


Baconguis Lab elucidates ENaC structure

Group photo of Sigrid Noreng, Richard Posert, Isabelle Baconguis, Ph.D., Arpita Bharadwaj and Craig Yoshioka, Ph.D. (Photo credit: OHSU/Kristyna Wentz-Graff)Work by Noreng and colleagues in the Baconguis Lab unveils the first three-dimensional structure of human epithelial sodium channel (ENaC) using cryo-electron microscopy. The findings, published in eLife, settle long-standing questions about the channel stoichiometry and arrangement, providing unprecedented insight into the molecular basis of ENaC function. The landmark study reveals critical sites of channel regulation, shedding light into the unique functional property of ENaC, an ion channel that opens in response to proteolysis. First author Sigrid Noreng is a graduate student in OHSU's Program in Molecular and Cellular Biosciences. (Photo credit: OHSU/Kristyna Wentz-Graff)
Watch the interview on Portland's KATU News
Read the article at OHSU News
Read coverage in Genetic Engineering & Biotechnology News