Pancreatic Atlas Research

The Brenden-Colson Center for Pancreatic Care is examining our patients' individual pancreatic tumors and other tissue in many different ways to produce an "Atlas" of pancreatic disease: a storehouse of clinical and basic science research data on each sample and each patient. We use this extensive data to provide insight into the biology of pancreatic disease, predict response to therapies, and tailor the treatment to the patient.

Our Atlas contains complete analysis of specimens from all of our patients, including:

  • Genetic and protein analysis
  • Study of the role of the immune system and the tumor microenvironment
  • Tumor structure imaging at a very high magnification
  • Model systems that mimic how disease works (for example, cultured cells)
  • Monitoring patient response
Atlas Project Workflow Overview Diagram: comprehensive molecular analysis and patient-derived tumor models, integrated database, new discoveries, translational tumor board, early detection/advanced therapeutics/quality of life, patient samples

In order to understand and track all this data, we are combining our research analysis with clinical information on our participating patients into a single database that can be used by both researchers and doctors. We can also compare our data to a broad population of patients around the world to strengthen our analyses, working closely with the scientists of OHSU's Computational Biology program to uncover which results are the meaningful ones.

For more information, visit the Brenden-Colson Center webpage.