Welcome to the Laura Heiser Lab

The long-term goal of the Heiser Lab is to design smarter therapies that improve outcomes for patients with hard-to-treat cancers. Toward that goal, we integrate cutting-edge imaging, single-cell sequencing, and computational modeling to develop frameworks for predicting and overcoming therapeutic resistance in cancer. Our in silico computational models provide a strategic advantage that accelerate discovery by enabling hypothesis testing and prioritization of therapeutic strategies. A central focus of our efforts has been on cellular heterogeneity and tumor–microenvironment interactions, areas that are critical for advancing precision medicine in challenging cancers such as triple-negative breast cancer. These contributions span both methodological innovation and translational impact, establishing new paradigms that advance fundamental science while informing therapeutic development.