Welcome to the Zuckerman Research Group
The Zuckerman group uses physics-based computational methods to study molecular, meso- and cell-scale systems. Starting from force laws for individual atoms, molecular simulation can provide a detailed picture of nano-scale biological behavior and aid rational drug design. The group develops and applies simulation methods to access important biological timescales and behaviors — such as protein conformational changes associated with ligand binding. The group also uses kinetic models to study "meso-scale" molecular machines, with a focus on the rotary ATPases which remarkably can act as proton pumps or ATP synthases. A new area of interest is modeling complex cellular morphologies and behaviors observed in cancer cells. All the group's work is underpinned by statistical physics and thermodynamics, which govern nano- to micro-scale biology.
- Statistical Physics of Biomolecules, a textbook by Daniel Zuckerman.
- Physical Lens on the Cell: Basic Principles Underlying Cellular Processes, an online book by Daniel Zuckerman.
- Statistical Biophysics Blog: Statistical mechanics in biology and biocomputation, by Daniel Zuckerman.
- WESTPA (Weighted Ensemble Simulation Toolkit with Parallelization and Analysis) software
- One-page Guide to Science Writing, by Daniel Zuckerman
Daniel Zuckerman Ph.D.
2730 S.W. Moody Avenue, room #3N016, Portland, Oregon 97201
Mailing and physical address:
Mail code: CL3G
2730 S.W. Moody Avenue
Portland, OR 97201