Omic and Multidimensional Spatial (OMS) Human Tumor Atlas

A National Cancer Institute initiative

The Omic and Multidimensional Spatial (OMS) Atlas is one of several "U2C" Human Tumor Atlases (HTA) Research Centers of the National Cancer Institute (NCI) Human Tumor Atlas Network, which emerged out of the Beau Biden Cancer Moonshot Initiative. The purpose of the construction of these "atlases" is to provide a more comprehensive understanding of the "ecosystems of tumors at the macro- and micro-level" by describing changes in cellular, structural, and molecular characteristics of human cancers as they progress over time.

Multi-institutional collaboration

The OMS Atlas lead investigators are: Joe Gray, Ph.D., Gordon Mills, M.D., Ph.D., Jeremy Goecks, Ph.D., and Christopher Corless, M.D., Ph.D. and our team includes collaborators from Harvard Medical School and the MD Anderson Cancer Center, who will work together to develop "maps" of human metastatic breast cancers.

Utilizes SMMART program infrastructure and data

Newly established in fall of 2018, it will take advantage of the clinical infrastructure in the SMMART program and support extensive characterization of tissues collected therein.

Research figure from OMS Atlas Research Center
Spatially defined omic analyses of breast cancers. LEFT: Genomic analyses, or DNA sequencing results from single cells of two different types of breast cancer. RIGHT: The areas from which these single cells were derived from the cancer biopsy.

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Inquiries

Please direct any inquiries regarding the Omic and Multidimensional Spatial (OMS) Human Tumor Atlas to Heidi Feiler, Scientific Program Manager, feiler@ohsu.edu.

News

  • A member of our OMS Atlas Team (Nick Navin from MDACC) was interviewed by NCI. The story "Meticulous Reconstructions of Tumor Origins With Single-Cell DNA Sequencing: Researcher Interview with Nicholas Navin" posted to the NCI Insights & Innovations blog on November 27, 2018. View the transcript.