A systems biology approach to understanding and treating cancer
OCCSB involves top scientists from across many disciplines to develop better methods of detecting and treating cancers. A systems biology approach means a comprehensive look at all spatial scales, from the tiniest (molecular level) through the whole person, over time. Learn more about the OCSSB.
News
- Gibbs Lab nerve fluorophore highlighted as ACS meeting, written up in CEN (4/2). Read more
- OPB on SMMART: OHSU Knight Cancer Institute Throws Out Old System Of Clinical Trials (3/21). Read more
- U.S. Patents awarded to both Summer Gibbs and Xiaolin Nan (2/21). Read more
- Technology Transfer names Summer Gibbs New Inventor of the Year (2/21). Read more
- The Mark Foundation names ASPIRE Award recipient, Summer Gibbs (2/20). Read more
- Beatty paper is OHSU School of Medicine Paper of the Month (2/5). Read more
Centers within the OCSSB
Multiple OCSSB projects have been designated national Research Centers by the National Cancer Institute (NCI) or the National Institute of Health:
- The Measuring, Modeling, and Controlling Heterogeneity (M2CH) Center for Cancer System Biology, a U54 Reseach Center of the NCI Cancer Systems Biology Consortium.
- Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers, or OMS Atlas, an NCI Human Tumor Atlas Network (HTAN) Research Center.
- The Pacific Northwest Center for Cryo-EM (PNCC), a National CryoEM Center.
- The Microenvironment Perturbagen (MEP) NIH Library of Integrated Network-based cellular signature Center, known as LINCS.
Learn more about OCSSB research.
Publication highlights
- Circulating Tumor DNA Dynamics using Patient-Customized Assays are Associated with Outcome in Neoadjuvantly-Treated Breast Cancer. doi: 10.1101/mcs.a003772.
- Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity. doi: 10.1002/cyto.a.23726.
- Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting. doi: 10.1016/j.celrep.2018.12.090.
- Implementing a comprehensive translational oncology platform: from molecular testing to actionability. doi: 10.1186/s12967-018-1733-y.