A systems biology approach to understanding and treating cancer
OCCSB involves top scientists from across many disciplines to develop better methods of detecting and treating cancers. A systems biology approach means a comprehensive look at all spatial scales, from the tiniest (molecular level) through the whole person, over time. Learn more about the OCSSB.
News
- John Muschler awarded travel funds to showcase innovation in bladder cancer (OHSU Research News, April 11)
- Gibbs Lab nerve fluorophore highlighted as ACS meeting, written up in CEN (4/2). Read more
- OPB on SMMART: OHSU Knight Cancer Institute Throws Out Old System Of Clinical Trials (3/21). Read more
- U.S. Patents awarded to both Summer Gibbs and Xiaolin Nan (2/21). Read more
- Technology Transfer names Summer Gibbs New Inventor of the Year (2/21). Read more
- The Mark Foundation names ASPIRE Award recipient, Summer Gibbs (2/20). Read more
- Beatty paper is OHSU School of Medicine Paper of the Month (2/5). Read more
Centers within the OCSSB
Multiple OCSSB projects have been designated national Research Centers by the National Cancer Institute (NCI) or the National Institute of Health:
- The Measuring, Modeling, and Controlling Heterogeneity (M2CH) Center for Cancer System Biology, a U54 Reseach Center of the NCI Cancer Systems Biology Consortium.
- Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers, or OMS Atlas, an NCI Human Tumor Atlas Network (HTAN) Research Center.
- The Pacific Northwest Center for Cryo-EM (PNCC), a National CryoEM Center.
- The Microenvironment Perturbagen (MEP) NIH Library of Integrated Network-based cellular signature Center, known as LINCS.
Learn more about OCSSB research.
Publication highlights
- Circulating Tumor DNA Dynamics using Patient-Customized Assays are Associated with Outcome in Neoadjuvantly-Treated Breast Cancer. doi: 10.1101/mcs.a003772.
- Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity. doi: 10.1002/cyto.a.23726.
- Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting. doi: 10.1016/j.celrep.2018.12.090.
- Implementing a comprehensive translational oncology platform: from molecular testing to actionability. doi: 10.1186/s12967-018-1733-y.
Multiscale Microscopy Core housed within OCSSB
The Multiscale Microscopy Core is a state-of-the-art electron microscopy research core established in 2013 by the OCSSB and FEI (now ThermoFisher Scientific). The MMC provides electron microscopy, related imaging services and technical support to both academic and industry professionals. Learn more about the MMC.