Our mission is to promote and facilitate epigenetics research and education across students, faculty, and physicians. The KCVI Epigenetics Consortium is directed by Dr. Lucia Carbone and includes several investigators whose research involves various aspects of epigenetics (e.g., environmental epigenetics, cancer, maternal reprogramming, neuroscience, reproductive biology).
Enabling epigenetics research
In order to facilitate epigenetics research, the Epigenetics Consortium includes a service core. This service core functions on a fee-for-service basis, with a sample-to-data model in mind.
Investigators inside and outside of OHSU can choose our wet-lab services, dry-lab services, or both. The service core provides end-to-end support for a number of DNA methylation and chromatin analyses. These services include, but are not limited to, bisulfite sequencing and chromatin immunoprecipitation sequencing (ChIP-seq).
Life cycle of a project
- Check out the recording of our recent virtual seminar with Dr. Steve Henikoff on chromatin dynamics.
- Save the date for our inaugural epigenetics symposium on October 22, 2020.
The Carbone lab was awarded one of the UO-OHSU pilot grants in collaboration with Dr. Kirstin Sterner. Their project will be using the epigenetic clock to test gene x environmental interactions in the context of brain aging and neurodegenerative diseases.
Apply for the SOM Innovation award to fund your epigenetics project!
Dr. Cheryl Maslen has been awarded a NIH R21 grant to investigate "Epigenetic Contributions to Bicuspid Valve Aortopathy in Turner Syndrome."