Integrated Pathology Core Services
The IPC offers several research services to investigators at and beyond OHSU.
Consultation and support services
Routine histology services
Advanced histology services
Histology equipment
Imaging services
Imaging equipment
Digital analysis tools
- Pre-project planning
- Expert consultation
- Method documentation
- Publication preparation
- Routine and customized tissue processing
- Embedding, sectioning (including large format blocks)
- Routine hematoxylin and eosin staining
- Frozen sectioning
- Custom sectioning: serial, step, large format
- Special histochemical stains
- Cassette and slide printing
- Bench top and automated immunohistochemistry
- Antibody optimization
- Multiplex immunohistochemistry
- RNAscope and DNAscope In Situ Hybridization
- Extensive portfolio of antibodies and In situ Hybridization probes validated for use in macaques
- Tissue processors
- Leica cassette labeler
- Leica slide printer, automated cover-slipper, ans auto-stainer
- Semi-automated and manual rotary microtomes
- Biocare IntelliPATH automated immunohistochemistry platform
- Fluorescence imaging: confocal, wide-field, and deconvolution microscopy
- Special fluorescence techniques: FURA-2, FRET, FRAP, and live-cell time-lapse imaging
- Large-area image montages: color bright field or fluorescence, including 3D confocal
- Neuron tracing and dendrites/spines analysis
- Cell mapping
- Image processing, 3D rendering, movies
- Quantitative image analysis and stereology
- Laser capture microdissection
- Leica Aperio AT2 400 slide scanner
- Olympus VS120 bright field and fluorescent slide scanner
- Leica Stellaris 8 confocal microscope
- MBF Bioscience Stereology System
- ArcturusXT Laser Capture Microdissection System
- HALO Image Analysis: HALO, HALOLink, HALO AI
- MBF Bioscience Stereology System with StereoInvestigators and NeuroLucida
- Olympus CellSens
- P-E Volocity
- FIJI/ ImageJ