Integrated Pathology Core Services

The IPC offers several research services to investigators at and beyond OHSU.

  • Pre-project planning
  • Expert consultation
  • Method documentation
  • Publication preparation
  • Routine and customized tissue processing
  • Embedding, sectioning (including large format blocks)
  • Routine hematoxylin and eosin staining
  • Frozen sectioning
  • Custom sectioning: serial, step, large format
  • Special histochemical stains
  • Cassette and slide printing
IPC_Histology_automated stainer
  • Bench top and automated immunohistochemistry
  • Antibody optimization
  • Multiplex immunohistochemistry
  • RNAscope and DNAscope In Situ Hybridization
  • Extensive portfolio of antibodies and In situ Hybridization probes validated for use in macaques
  • Leica cassette labeler
  • Leica slide printer
  • Leica automated cover slipper
  • Semi-automated and manual rotary microtomes
  • Biocare Intellipath automated immunohistochemistry platform
IPC_Imaging_Aperio whole slide scanner
  • Fluorescence imaging: confocal, wide-field, and deconvolution microscopy
  • Special fluorescence techniques: FURA-2, FRET, FRAP, and live-cell time-lapse imaging
  • Large-area image montages: color bright field or fluorescence, including 3D confocal
  • Neuron tracing and dendrites/spines analysis
  • Cell mapping
  • Image processing, 3D rendering, movies
  • Quantitative image analysis and stereology
  • Laser capture microdissection
  • Leica Aperio AT2 400 slide scanner
  • Olympus VS120 bright field and fluorescent slide scanner
  • Leica SP5 AOBS multi-spectral confocal microscope
  • MBF Bioscience Stereology System
  • ArcturusXT Laser Capture Microdissection System
  • HALO Image Analysis: HALO, HALOLink, HALO AI
  • MBF Bioscience Stereology System with StereoInvestigators and NeuroLucida
  • Olympus CellSens
  • P-E Volocity
  • FIJI/ ImageJ