Chemical Biology and Physiology 2025
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December 11 – 13, 2025 Chemical Biology and Physiology Conference | Portland, Oregon, USA
December 11 - 13, 2025 | Portland, Oregon, USA
Chemical Biology and Physiology 2025 is the fifth offering of a biennial international conference series focused on the growing intersection of Chemical Biology and Physiology. The interaction of Chemical Biology and Physiology is based on the need for new tools that are applicable in complex systems and provides innovative opportunities for drug target discovery and novel therapeutic concepts. This conference brings together leading scientists from around the world to promote inspiration and collaboration to stimulate cutting edge research in this exciting research nexus.
Keynote Speakers
Matt Bogyo - Stanford University
Nancy Carrasco, M.D. - Vanderbilt University
Christopher Chang - Princeton University
Speakers
Jeremy M. Baskin, Ph.D. - Cornell University
George Burslem - University of Pennsylvania
Gonzalo Cosa, Ph.D. - McGill University
Bianxiao Cui - Standford University
Sheel Dodani - University of Texas - Dallas
Matthew B. Francis - University of California – Berkeley
Summer Gibbs - Oregon Health & Science University
Josh Levitz - Cornell University
David E. Olson - University of California – Davis
Nicole Sampson - University of Rochester
Stephan A. Sieber - Technical University of Munich
Ellen Sletten - University of California – Los Angeles
Ben Swarts - Central Michigan University
Fikadu Tafesse - Oregon Health & Science University
Ed Tate - Imperial College London & Francis Crick Institute
Aiko Umeda - Amgen, Inc.
Yasuteru Urano - The University of Tokyo
Xin Zhou - Dana-Farber Cancer Institute | Harvard Medical School
Steering Committee
Kimberly Beatty, Ph.D., Oregon Health & Science University
Victoria DeRose, Ph.D., University of Oregon
James Frank, Ph.D., Oregon Health & Science University
Ryan Mehl, Ph.D., Oregon State University
Carsten Schultz, Ph.D., Oregon Health & Science University
Organizers
Contact the organizers: chembiophysinquiries@ohsu.edu
Registration Rates
| Rate | |
|---|---|
| Academia | $600 USD |
| Industry | $750 USD |
| 08:00 – 08:55 | Check-in and Welcome |
|---|---|
| 08:55 – 09:00 | Opening Remarks |
| SESSION 1: CHEMICAL BIOLOGY TOOLS - Chair: Kimberly Beatty | |
|---|---|
| 09:05 – 09:35 | Xin Zhou, Dana Farber Cancer Institute, Harvard Medical School - When antibodies become degraders |
| 09:35 – 10:10 | Ellen Sletten, UC Los Angeles - In vivo imaging with shortwave infrared light |
| 10:10 – 10:25 | Short-Talk: John Koberstein, Janelia Research Campus - Molecular Tools and Imaging |
| 10:25 – 10:55 | Break |
| 10:55 – 11:30 | Ed Tate, Imperial College, London - Targeting post-translational modification in drug discovery |
| 11:30 – 11:45 | Juner Zhang, Princeton - Isotope-Enhanced Chemoproteomic Profiling of Endogenous Protein Serotonylation |
| 11:45 – 12:15 | Flash Talks: 20 Poster presenters |
| 12:15 – 13:15 | Lunch - Meet the speakers |
| 13:15 – 14:45 | Poster Session I |
| SESSION 2: CHEMICAL PHYSIOLOGY - Chair: James Frank | |
|---|---|
| 14:45 – 15:20 | Josh Levitz, Weill-Cornell - Pinpointing therapeutic mechanisms of neuromodulatory GPCRs |
| 15:20 – 15:55 | Bianxiao Cui, Stanford University - Membrane curvature-induced integrin adhesion and drug development |
| 15:55 – 16:10 | Short-Talk: Tanya Hadjian, University of California, Irvine - Continuous hypermutation and evolution of novel luciferase variants |
| 16:10 – 16:45 | David Olson, UC Davis - Psychedelics and Related Plasticity-Promoting Neurotherapeutics |
| 16:45 – 17:00 | Break |
| Keynote Session - Chair: Leif Lindberg | |
|---|---|
| 17:00-18:00 | Nancy Carrasco, Vanderbilt University - The tale of the sodium/iodide symporter (NIS): From cloning to structure |
| 18:00-20:30 | Reception |
| SESSION 3: CHEMICAL BIOLOGY OF LIPIDS - Chair: Carsten Schultz | |
|---|---|
| 09:00 – 09:35 | Summer Gibbs, Oregon Health & Science University - Novel Fluorescent Contrast Agents to Improve Clinical Medicine |
| 09:35 – 10:10 | Jeremy Baskin, Weill-Cornell - Revealing Mechanisms of Lipid Homeostasis Using Membrane Editing and Proximity Proteomics |
| 10:10 – 10:25 | Pankaj Gaur, Université de Strasbourg, France - Environment-sensitive and red light activatable cage for biological application |
| 10:25 – 10:55 | Break |
| 10:55 – 11:30 | Benjamin Swarts, Central Michigan State University - Synthetic lipids for probing the mycobacteria-host interface |
| 11:30 – 11:45 | Ben Barad, Oregon Health State University - Surface Morphometrics 2.0: Incorporating Protein Localization and Density Sampling for Contextual Structural Analysis with Cryo-electron Tomography |
| 11:45 – 12:15 | Flash Talks: 20 Poster presenters |
| 12:15 – 13:15 | Lunch - Meet the Speakers |
| 13:15 – 14:45 | Poster Session II |
| SESSION 4: CHEMICAL BIOANALYTICS - Chair: Vickie DeRose | |
|---|---|
| 14:45 – 15:20 | Gonzalo Cosa, McGill University, Toronto - A window into lipid peroxyl radicals, peroxidation and lipid-derived electrophilic stress in cells |
| 15:20 – 15:55 | Yasuteru Urano, Tokyo University - Development of novel chemistry-based and enzyme-driven theranostics technologies for cancer |
| 15:55 – 16:10 | Klara Gries, Max Planck Institute for Medical Research - Toward multiplexed recordings with split self-labeling protein tags |
| 16:10 – 16:45 | Sheel Dodani, University of Texas Dallas - An optical lense at chloride in biology |
| 16:45 – 17:00 | Break |
| Keynote Session - Chair: Tatum Weishaar | |
|---|---|
| 17:00-18:00 | Keynote Speaker: Chris Chang, Princeton University - Engineering proteins to map and manipulate cells |
| 18:00 | Free evening |
| 19:00 | Speaker Dinner |
| SESSION 5: CHEMICAL BIOLOGY OF PATHOGENS - Chair: Kimberly Beatty | |
|---|---|
| 09:00 – 09:35 | Stephan Sieber, Technische Universitaet Muenchen - Chemical dysregulation to break bacterial resistance |
| 09:35 – 10:10 | Nicole Sampson - Tuberculosis Target Discovery in Secondary Metabolic Pathways |
| 10:10 – 10:25 | Short-Talk: Katelyn Alley: University of Oregon - Dual-Protein and Click Expansion Microscopy Reveal Nanoscale Reorganization of the Nucleolus during Stress |
| 10:25 – 10:55 | Break |
| 10:55 – 11:30 | Fikadu Tafesse, Oregon Health & Science University - Studying Host-Pathogen Interactions Using Lipid Probes |
| 11:30 – 11:45 | Short-Talk: Peter Tonge, Stony Brook University - Drug-target residence time and the post-antibiotic effect: Strategies to improve dosing regimens |
| 11:45 – 12:15 | Flash Talks: 20 poster presenters |
| 12:25 – 13:15 | Lunch - Meet the Speakers |
| 13:15 – 14:45 | Poster Session III |
| SESSION 6: - PROTEIN CHEMISTRY Chair: Ryan Mehl | |
|---|---|
| 14:45 – 15:20 | Matt Francis, UC Berkeley - Synthetically Modified Viral Capsids as Efficient Delivery Platforms for STING Agonists |
| 15:20 – 15:55 | Aiko Umeda, Amgen - Genetic Code Expansion Enables Antibody–Protein Conjugates with Previously Inaccessible Architectures and Enhanced Functionality |
| 15:55 – 16:10 | Short-Talk: Dora Kern, HUN-REN Research Centre for Natural Sciences - Bioorthogonally activated protein labelling |
| 16:10 – 16:45 | George Burslem, University of Pennsylvania - Intracellular protein editing |
| 16:45 – 17:00 | Break |
| Keynote Session - Chair: Moriah Mathis | |
|---|---|
| 17:00 – 18:00 | Keynote Speaker: Matt Bogyo, Stanford University - Lessons from Collagen: Chemical Biology in the Extracellular Matrix |
| 18:00 | Poster Prize Presentations |
| 18:10 | Closing Remarks |
| 18:15 | Evening social |
* Abstract Submission Is Now Closed *
Only registered participants attending in person are eligible to submit an abstract and present a poster. Poster presentations will not be available to virtual participants. If you are presenting a poster, you must also register for the conference.
Abstract submission deadline is October 30, 2025 to be considered for a Short Talk. See below for further details.
Short Talks:
Nine short talks will be selected from the abstract submissions received on or before October 30, 2025. A short talk is a 12-minute presentation with slides on the poster topic, given from the main stage. A short talk allows the presenter to go into details about the poster research to all attendees. Short Talk presenters will be notified 2-3 weeks after the abstract review.
Flash Talks:
The first 60 abstracts received will be eligible to give a flash-talk. A flash talk is a 90-second presentation of your poster, supported by a single slide, from the main stage. Flash talks are an opportunity to promote your poster topic prior to the poster session. Flash Talk presenters will be notified after the abstract review.
General Information:
- Finished poster size should be no larger than 48" vertical x 48" horizontal.
- The character limit for abstracts is 4,000 characters (including spaces).
- Abstracts may be edited up to the deadline of October 30, 2025. Abstracts will be included in the abstract book as entered as of this date. To change any abstract information previously submitted, please email the conference organizers at chembiophysinquiries@ohsu.edu.
- Please proof your abstract carefully for spelling and data errors. Pay special attention to the author order and presenting author designation.
- Submission of an abstract conveys permission to be included in the abstract book and posted online.
- All abstract submissions must be submitted electronically through the abstract system.
Venue
Knight Cancer Research Building
Oregon Health & Science University
2720 S.W. Moody Ave.
Portland, OR 97201
Accommodations
Downtown Portland has many hotels and lodging options conveniently connected by light rail, Portland street car, and bus lines.
The recommended hotel for the conference is the Hyatt House Portland Downtown. The hotel is conveniently located .3 miles from the venue, within easy walking distance. Hyatt House is offering a discounted rate of $119/night for a standard room, book now using this link!
Hyatt House Portland Downtown
2080 SW River Drive
Portland, OR 97201
503-241-2775
Map
Additional lodging options include:
Local Transportation
The conference venue is just south of downtown Portland, Oregon, and easily accessible by the Portland Streetcar and MAX light rail. This makes most downtown Portland hotels a convenient choice for conference accommodations.
To discuss interest in conference sponsorship, or for sponsorship questions, please contact Carsten Schultz, schulcar@ohsu.edu.
Platinum Sponsor - $6,000 ($3,000 may be tax deductible as a charitable contribution)
One sponsorship available at this level.
- Named Conference Reception held on the first night of the conference. (value $1,250)
- Two (2) conference registrations. (value $1,500)
- Sponsor table with tablecloth. (value $100)
- Sponsor slide included in rotating slide deck. (value $50)
- Flash-talk spot. (value $50)
- Organization logo on conference webpage, booklet and welcome slide. (value $50)
- Distribute flyers/brochures at conference.
Poster Session Sponsor - $3,500 ($1,300 may be tax deductible as a charitable contribution)
Two sponsorships available at this level.
- One (1) conference registration. (value $750)
- Named poster session. (value $800)
- Poster awards: $300/$200/$100. (value $600)
- Sponsor representative presents the awards.
- Organization logo on conference webpage, booklet and welcome slide. (value $50)
- Distribute flyers/brochures at conference.
Gold Sponsor - $3,500 ($1,800 may be tax deductible as a charitable contribution)
Eight sponsorships available at this level.
- One (1) conference registration. (value $750)
- Named science session or keynote session. (value $700)
- Sponsor table with tablecloth. (value $100)
- Sponsor slide included in rotating slide deck. (value $50)
- Flash-talk spot. (value $50)
- Organization logo on conference webpage, booklet and welcome slide. (value $50)
- Distribute flyers/brochures at conference.
Silver Sponsor - $2,000 ($1,050 may be tax deductible as a charitable contribution)
Six sponsorships available at this level.
- One (1) conference registration. (value $750)
- Named coffee session. (value $150)
- Organization logo on conference webpage, booklet and welcome slide. (value $50)
- Distribute flyers/brochures at conference.
Bronze Supporter - $800 ($750 may be tax deductible as a charitable contribution)
Unlimited sponsorships at this level.
- Organization logo on conference webpage, booklet and welcome slide. (value $50)
- Distribute flyers/brochures at conference.
Customized Sponsorship Package - $TBD
Unlimited sponsorships at this level.
We are happy to customize a sponsorship package that meets your budget and interests. To discuss customizing your sponsorship package, or modify one of the above packages, please contact Carsten Schultz, schulcar@ohsu.edu.