Instruments at South Waterfront

The ALM Core has a number of different imaging setups that excel at different applications. Below is an overview of instruments located in the Knight Cancer Research Building. 

See our Services page for a full list of instruments by modality.

Laser Scanning Confocal

full image of super resolution laser scanning confocal microscope from Ziess

Zeiss LSM 880. Laser scanning confocal microscope on an inverted imaging stand. Our laser scanners are equipped with objectives that have high numerical apertures for optimal multi-color imaging and optical sectioning.

Spinning Disk Confocal

Yokogawa CSU-X1 on Zeiss Axio Observer. Spinning disk confocal microscope on an inverted imaging stand. Spinning disk confocal imaging outperforms laser-scanning microscopy for live-cell imaging. This setup accepts mutli-well plates for image-based screening assays.

Sheet Illumination

Zeiss Lightsheet Z.1 for aqueous and CLARITY imaging. Sheet illumination allows for imaging of clarified, thick samples. The same system can also be converted into a setup for fast 3D imaging of live specimens.

High Resolution Widefield

Zeiss AxioScan.Z1 Slide Scanner. Fully automated imaging of routine histological and fluorescent sections.

Super Resolution Microscopy

Zeiss LSM 880 with Airy and Fast Airyscan. This system uses Zeiss’ Airyscan detector to capture super resolved confocal images on an inverted imaging stand. This setup also has a chameleon laser for 2-photon excitation, as well as a BiG.2 Detector for FRET/FLIM experiments.