The ALM Core has a number of different imaging setups that each excel at different applications. Below is an overview of instruments located in the Knight Cancer Research Building. See About for more location information.
- Zeiss LSM 880 on inverted microscope stand
Our laser-scanning confocal microscopes are equipped with highly corrected objectives with high-numerical apertures for optimal multi-color imaging and optical sectioning.
Spinning Disk Confocal
- Yokogawa CSU-X1 on Zeiss AxioObserver
Spinning disk confocal microscopy outperforms laser-scanning microscopy for live-cell imaging. These setups accept mutli-well plates for image-based screening assays.
- Zeiss Lightsheet Z.1 for aqueous and CLARITY imaging
Large live specimens can be imaged without toxicity long-term. The same system can be converted into a setup for fast 3D imaging of cleared tissues.
High Resolution Widefield
Fully automated imaging of routine histological specimens.
- Zeiss LSM 880 with Airyscan and Fast Airyscan
Structured illumination-based and Airyscan super-resolution microscopy are very accessible super-resolution technologies. One of our setups is also equipped for single-molecule localization techniques, such as PALM and STORM.
Image Analysis and Presentation
We have several high-end workstations with image analysis and processing software suites to analyze and present your multi-dimensional data.
- Learn more about our analysis suite.