Psilocybin for Chronic Pelvic Pain (CPP)

An artistic rendition of a pastel blue-colored person surrounded by wildflowers with an overlayed depiction of a darker blue anatomical pelvis in the abdominal area.

Psilocybin is the active ingredient in psychedelic mushrooms. This study is investigating a single administration of psilocybin with psychotherapy sessions to treat chronic pelvic pain (CPP) conditions. 

Participation includes 10 visits over about 6 months. There are 4 OHSU clinic visits to confirm eligibility and assess general health. There are 6 visits at Portland Psychotherapy which include two preparatory sessions (the first session can be virtual), a dosing session, and 3 integration sessions (the last two visits can be virtual).

Eligibility

You may be eligible to participate in this study if you:

  • Were assigned female at birth and are between the age of 21 and 45
  • Have been diagnosed by a doctor with chronic pelvic pain (endometriosis, adenomyosis, uterine fibroids, pelvic congestion, other pelvic inflammatory diseases, irritable bowel syndrome, inflammatory bladder disorders, myalgias)
  • Have experienced pelvic pain for at least 6 months
  • Have tried at least one prior treatment for pain without success
  • Are not pregnant and are willing to use contraception during study participation

Please note there are additional study criteria to be eligible.

Compensation

Participants will be compensated $50 for each of the four OHSU clinic visits for a total of up to $200.

Contact Information

To find out more information and to learn if you are qualified to participate, fill out the online form or call the Women’s Health Research Unit confidential recruitment line at 503-494-3666 or email us at whru@ohsu.edu.

Contact us

Call the Women’s Health Research Unit confidential recruitment line at 503-494-3666 or email us at whru@ohsu.edu.

About the study