Endometrial Responses to GLP-1 Agonist Use and Bariatric Surgery
What is this study about?
The purpose of this study is to understand the impact of GLP-1 agonist medication (used for weight loss, e.g., Wegovy, Zepbound) and bariatric surgery (weight loss surgery, e.g., gastric bypass) on the menstrual cycle. If you join, we will ask to take a small tissue sample from the lining of your uterus two times. We will also ask you to answer questions in a daily text message diary. Being in this study will take about 7 months.
During each study visit, we will:
- Collect a sample of uterine lining
- Do a blood draw
- Ask about your health and any medicine you take
We are looking for people who:
- Are 18 to 45 years old
- Have regular periods
- Have a Body Mass Index (BMI) over 30
- Are already planning to start a GLP-1 agonist medication or to have bariatric surgery
You will be paid up to $1,035 for your time and travel.
Contact Us
If you are interested in participating in the study, contact the Women’s Health Research Unit at whru@ohsu.edu, call us at 503-494-3666, or fill out this form: https://www.ohsu.edu/womens-health/contact-womens-health-research-unit.