Biography

Research interests: Immunology, cancer immunotherapy, tumor microenvironment, and biomaterial-based drug
delivery

Clinical interests: Subspecialities of internal medicine (oncology, critical care, and pulmonology) and
interventional radiology

Rohan Chaudhari is a MD-PhD student studying mechanisms regulating T cell immunity against lung cancer
under the mentorship of Dr. Megan Burger Ph.D. He is interested in better understanding the role of antigen
immunodominance in T-cell function and remodeling antigen hierarchies using therapeutic vaccination.

He attended UCLA, where he studied Molecular Biology. At UCLA, he worked in the lab of Dr. Kathrin Plath
Ph.D. studying X-chromosome inactivation in human germ cells and the role of long non-coding RNAs XIST
and XACT in the process. Following graduation, Rohan joined the National Institute of Cancer under the
tutelage of Dr. Mathew Wolf Ph.D. studying the immunomodulatory properties of ECM biomaterials and their
use in delivering cancer vaccines against melanoma.

Outside of science, Rohan is an avid reader and loves to play video games and board games with friends.
Rohan is also a huge fan of the San Francisco 49ers and has spent the last ten years watching his favorite
team lose a total of 3 Super Bowls (we’ll get em next time!).

Selected publications

Chitiashvili T., Dror I., Kim R., Hsu F. M., Chaudhari R, et al. Female human primordial germ cells display
X-chromosome dosage compensation despite the absence of X-inactivation. Nat Cell Biol.
2020;22(12):1436-1446. https://doi:10.1038/s41556-020-00607-4

Lokwani, R., Chaudhari, R., Wolf, M.T. et al. Spectral cytometry on highly autofluorescent samples. Nat
Rev Methods Primers 2, 71 (2022). https://doi.org/10.1038/s43586-022-00156-0

S. Pal, R. Chaudhari, I. Baurceanu, B. J. Hill, B. A. Nagy, M. T. Wolf, Extracellular Matrix Scaffold-
Assisted Tumor Vaccines Induce Tumor Regression and Long-Term Immune Memory. Adv. Mater. 2024,
2309843. https://doi.org/10.1002/adma.202309843