Research
The Harold Schnitzer Diabetes Health Center is committed to promoting research. Our goal is to enhance the quality of life of those living with diabetes.
Our efforts to find a cure for diabetes is made possible by volunteers who participate in research studies. When you volunteer, you help us answer important questions about diabetes.
If you would like to be considered as a potential volunteer for our research studies, please call 503-494-4704, complete our Online Diabetes Research Application Form or email DMResearchCenter@ohsu.edu for more information.
Current studies
ADJUST Study
Are You Interested in Participating in a Research Study to Learn More about the Potential of Semaglutide (brand name Ozempic) as a Treatment for Type 1 Diabetes?
This study is sponsored by the Juvenile Diabetes Research Foundation and Novo Nordisk. We are seeking volunteers who are currently using a hybrid closed loop system such as the t:slim X2 with Control IQ, Omnipod 5 or Medtronic 670/770G to test the use of a medication called Semaglutide (brand name Ozempic) to help treat type 1 diabetes. Semaglutide is a once weekly injection that may improve glucose control and weight loss.
The study consists of 6 clinic visits and 3 phone visits. After you qualify, you will continue to use your hybrid closed loop system as usual. In addition, you will be randomized to receive either Semaglutide or a placebo over 26 weeks. You will receive a physical exam and have some blood drawn during the clinic visits. We will also download your pump and continuous glucose monitor (CGM). You will be asked to complete several cardiovascular disease assessment procedures such as a cardiac MRI at two of the clinic visits.
Compensation for participation in all study visits and assessments is up to $925.
- You may be eligible to participate if you are:
- Diagnosed with type 1 diabetes for at least 12 months
- Between the ages of 18 and 60 years
- Using the T:slim X2 pump, Omnipod 5, Medtronic 760G or 770G for at least 3 months
- HbA1c 7.0% - 10.0% at time of screening
- Body mass index (BMI) ≥ 30 kg/m2
What is involved?
- IRB Approved: 3/30/2023
- 6 clinic visits and 3 phone visits
- The use of either Semaglutide or placebo for a once weekly injection at home
- To learn more about this study or find out if you’re eligible, please contact Brittany Caswell at 503-494-4704 or email diabtesresearch@ohsu.edu.
Oregon Health and Science University | Portland, Oregon
Phone: 503-494-4704
Email: diabetesresearch@ohsu.edu
OHSU IRB#: 25175
HSDHC Homepage: www.ohsu.edu/diabetes
Multi-site T1D Closed-Loop Study
Multi-site T1D Closed-Loop Study: Currently Seeking Adult Volunteers using t:slim X2 pump with Control IQ
This multi-site study is sponsored by OHSU with additional sites at University of Washington in Seattle and MultiCare Rockwood Northpointe Specialty Center in Spokane. We are seeking volunteers to test a new closed loop system for patients who are currently using the t:slim X2 pump with Control IQ. The purpose of this study is to test how well a new investigational closed loop system called iPancreas manages your blood sugar. The system uses a Dexcom G6 glucose sensor, the Omnipod insulin pump and a Polar M600 watch to determine rates of insulin to deliver. The system has the ability to detect when you forgot to enter your meal bolus insulin. You will complete two visits. For one visit, you will use our study device with Fiasp insulin starting with a 6 hour visit on campus followed by you using the system at home for 7 days. The other visit will require you to use your t:slim X2 pump with Control IQ with your own insulin for 7 days at home. Each site will enroll ~10 participants. Compensation is up to $600 for participating.
You may be eligible to participate if you are:
- Diagnosed with type 1 diabetes for at least one year
- Age 18 years and older
- Using the t:slim X2 pump with Control IQ active for at least 12 weeks
- HbA1c ≥ 7.5% at time of screening
- Live with another person age 18 or older who will sleep in the house at night
- Live within 40 miles of enrollment site
What is involved?
- 1.5 hour screening visit
- Two 7 day visits with one 6 hour in clinic visit
- Use the study device (Omnipod, Dexcom G6 and polar watch) with Fiasp insulin and your t:slim X2 pump with Control IQ enabled with your own insulin
- To learn more about this study or find out if you’re eligible, please contact one of the following:
Oregon Health and Science University | Portland, Oregon
Phone: 503-418-9070
Email: oregonapc@ohsu.edu
Advarra IRB# Pro00067326
OHSU IRB# 24218
HSDHC Homepage: