The OHSU Research Integrity Office (ORIO) is charged with protecting and assuring compliance under the laws that govern the rights and welfare of human and animal subjects, and the oversight of basic and applied scientific research at OHSU.

To complete this mission, ORIO is composed of five oversight committees: The Institutional Review Board (IRB), which oversees human subjects research; The Institutional Animal Care and Use Committee (IACUC), which governs research dealing with animals; The Institutional Biosafety Committee (IBC), who is charged with ensuring safety for all personnel working with rDNA, synthetic nucleic acid molecules, infectious agents, and toxins; and the Conflict of Interest in Research (CoIR) Committee whose primary mission is to review potential conflicts of interest and determine appropriate management. The Scientific Integrity Committee (SIC) reviews and acts on allegations of research misconduct, which is defined by federal law as falsification, fabrication or plagiarism in the conduct of science.

All those involved in research at OHSU must complete the CoIR disclosure and RCR education.