Curcumin Implant Study

The goal of this study is to learn if a supplement called curcumin, the active ingredient in the spice turmeric, taken for 30 days can reduce the number of days of vaginal bleeding in women using the contraceptive implant (nexplanon or implanon).

WHRU - Curcumin Implant Study

There are currently no medications approved to treat vaginal bleeding in women using the contraceptive implant. The drug we are studying, curcumin, has been shown to be anti-inflamatory, anti-proliferative (preventing cell growth), and anti-angiogenic (preventing new blood vessel growth). We want to learn if the study drug has an impact on bleeding in Implanon and Nexplanon users. The study drug, curcumin, is a supplement and therefore not regulated by the FDA.

You may be eligible if you:

  • Women between the ages of 15 and 45 who are current Nexplanon or Implanon users
  • Have frequent or persistent bleeding while using the implant
  • Have a cell phone that is capable of receiving text or email messages.
  • In general good health


Qualified participants may receive up to $250 for time and travel.

Whom do I contact for additional information?

To find out more information and to learn if you are qualified to participate, please call the Women's Health Research Unit confidential recruitment line at 503-494-3666 or email us at