Selected publications

Fresa K, Catandi GD, Whitcomb LA, Gonzalez-Castro RA, Chicco AJ, Carnevale EM. Adiposity in mares induces insulin dysregulation and mitochondrial dysfunction which can be mitigated by nutritional intervention. Sci Rep. 2024 Jun 18;14(1):13992. doi: 10.1038/s41598-024-64628-x. PubMed PMID: 38886475; PubMed Central PMCID: PMC11183153.

Gonzalez-Castro RA, Whitcomb LA, Pinsinski EC, Carnevale EM. Cryopreservation of equine spermatozoa reduces plasma membrane integrity and phospholipase C zeta 1 content as associated with oocyte activation. Andrology. 2024 May;12(4):918-931. doi: 10.1111/andr.13517. Epub 2023 Aug 22. PubMed PMID: 37608516.

Whitcomb LA, Cao X, Thomas D, Wiese C, Pessin AS, Zhang R, Wu JC, Weil MM, Chicco AJ. Mitochondrial reactive oxygen species impact human fibroblast responses to protracted γ-ray exposures. Int J Radiat Biol. 2024;100(6):890-902. doi: 10.1080/09553002.2024.2338518. Epub 2024 Apr 17. PubMed PMID: 38631047.

Catandi GD, Fresa KJ, Cheng MH, Whitcomb LA, Broeckling CD, Chen TW, Chicco AJ, Carnevale EM. Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation. Sci Rep. 2024 Mar 30;14(1):7571. doi: 10.1038/s41598-024-58323-0. PubMed PMID: 38555310; PubMed Central PMCID: PMC10981747.

Cao X, Thomas D, Whitcomb LA, Wang M, Chatterjee A, Chicco AJ, Weil MM, Wu JC. Modeling ionizing radiation-induced cardiovascular dysfunction with human iPSC-derived engineered heart tissues. J Mol Cell Cardiol. 2024 Mar;188:105-107. doi: 10.1016/j.yjmcc.2023.11.012. Epub 2024 Feb 29. PubMed PMID: 38431383; PubMed Central PMCID: PMC10961094.

Omar AK, Li Puma LC, Whitcomb LA, Risk BD, Witt AC, Bruemmer JE, Winger QA, Bouma GJ, Chicco AJ. High-fat diet during pregnancy promotes fetal skeletal muscle fatty acid oxidation and insulin resistance in an ovine model. Am J Physiol Regul Integr Comp Physiol. 2023 Nov 1;325(5):R523-R533. doi: 10.1152/ajpregu.00059.2023. Epub 2023 Aug 29. PubMed PMID: 37642284; PubMed Central PMCID: PMC11178291.

Parsons AM, Rajendran RR, Whitcomb LA, Bouma GJ, Chicco AJ. Characterization of trophoblast mitochondrial function and responses to testosterone treatment in ACH-3P cells. Placenta. 2023 Jun;137:70-77. doi: 10.1016/j.placenta.2023.04.011. Epub 2023 Apr 13. PubMed PMID: 37087951.

Bokhari RS, Beheshti A, Blutt SE, Bowles DE, Brenner D, Britton R, Bronk L, Cao X, Chatterjee A, Clay DE, Courtney C, Fox DT, Gaber MW, Gerecht S, Grabham P, Grosshans D, Guan F, Jezuit EA, Kirsch DG, Liu Z, Maletic-Savatic M, Miller KM, Montague RA, Nagpal P, Osenberg S, Parkitny L, Pierce NA, Porada C, Rosenberg SM, Sargunas P, Sharma S, Spangler J, Tavakol DN, Thomas D, Vunjak-Novakovic G, Wang C, Whitcomb LA, Young DW, Donoviel D. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sci Space Res (Amst). 2022 Nov;35:105-112. doi: 10.1016/j.lssr.2022.08.003. Epub 2022 Aug 7. PubMed PMID: 36336356.

Wang E, Whitcomb LA, Chicco AJ, Wilson JW. Transient absorption spectroscopy and imaging of redox in muscle mitochondria. Biomed Opt Express. 2022 Apr 1;13(4):2103-2116. doi: 10.1364/BOE.452559. eCollection 2022 Apr 1. PubMed PMID: 35519286; PubMed Central PMCID: PMC9045930.

Chatfield KC, Sparagna GC, Specht KS, Whitcomb LA, Omar AK, Miyamoto SD, Wolfe LM, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inherit Metab Dis. 2022 Jan;45(1):111-124. doi: 10.1002/jimd.12459. Epub 2021 Dec 7. PubMed PMID: 34821394.