Biography

Research: Pancreatic cancer, cancer metastasis, cachexia

Clinical: Medical Oncology

Selected publications

Olson, B., Zhu, X., Norgard, M.A., Levasseur, P.R., Butler, J.T., Buenafe, A., Burfeind, K.G., Michaelis, K.A., Pelz, K.R., Mendez, H., Edwards, J., Krasnow, S.M., Grossberg, A.J., Marks, D.L. “Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia.” Nature Communications, 2021, doi: 10.1038/s41467-021-22361-3.

Michaelis, K.A., Norgard, M.A., Zhu, X., Levasseur, P.R., Sivagnanam, S., Liudahl, S.M., Burfeind, K.G., Olson, B., Pelz, K.R., Angeles Ramos, D.M., Maurer, H.C., Olive, K.P., Coussens, L.M., Morgan, T.K., Marks, D.L. “The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer.” Nature Communications, 2019, doi: 10.1038/s41467-019-12657-w

Zhu, X., Burfeind, K.G., Michaelis, K.A., Braun, T.P., Olson, B., Pelz, K.R., Morgan, T.K., Marks, D.L. “MyD88 Signaling Is Critical in the Development of Pancreatic Cancer Cachexia.” Journal of Cachexia, Sarcopenia and Muscle, 2019, doi:10.1002/jcsm.12377.

Allen-Petersen, B. L., Risom, T., Feng, Z., Wang, Z., Jenny, Z.P., Thoma, M.C., Pelz, K.R., Morton, J.P., Sansom, O.J., Lopez, C.D., Sheppard, B., Christensen, D.J., Ohlmeyer, M., Narla, G., Sears, R.C. “Activation of PP2A and Inhibition of MTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma.” Cancer Research, vol. 79, no. 1, 2018, pp. 209–219., doi:10.1158/0008-5472.can-18-0717.

Arneson-Wissink, P. C., Mendez, H., Pelz, K., Dickie, J., Bartlett, A. Q., Worley, B. L., Krasnow, S. M., Eil, R., & Grossberg, A. J. Hepatic signal transducer and activator of transcription-3 signalling drives early-stage pancreatic cancer cachexia via suppressed ketogenesis. Journal of cachexia, sarcopenia and muscle, 2024, doi:10.1002/jcsm.13466.