OHSU Center for Women's Health

Where Healing, Teaching and Discovery Come Together

Examining the brain's control systems in overactive bladder using mindful based approach

Clinical Trial Seeking Participants

IRB 9405 (PI: W. Rahel Nardos, MD)

The Women’s Health Research Unit is conducting a study examining the brain's control systems in overactive bladder using mindful based stress reduction approach.

Trial status

Open to Enrollment

Why is this study being done?

Urgency incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder. New findings have discovered that urgency incontinence may be connected to the interactions of certain regions of the brain and the bladder. Although this is a common problem, researchers still do not know how these interactions impact the process of urgency incontinence. The purpose of this study is to better understand how mindfulness based stress reduction techniques may reduce urinary incontinence symptoms and if symptom reduction is related to changes in brain functioning. We will use Magnetic Resonance Imaging (MRI) machine and Diffusion Tensor Imaging (DTI) to create images of the brain during different bladder states.

Who is eligible to participate?

Women who are between the ages of 40 and 85 who:

  • Must be experiencing symptoms of urinary incontinence
  • Qualify based on your answers to a phone screening questionnaire.

What is the compensation for this study?

Participants are eligible to receive up to $150 for time and costs related to this study which requires two visit to OHSU lasting approximately 3 hours each.

Who do I contact for additional information?

To find out more information and to learn if you are qualified to participate call the Women’s Health Research Unit confidential recruitment line: 503-494-3666