Yantasee journal covers
Journal covers featuring Yantasee Lab research


Wang, R.; Kumar, P.; Reda, M.; Wallstrum, A. G.; Crumrine, N. A.; Ngamcherdtrakul, W.; Yantasee, W., Nanotechnology Applications in Breast Cancer Immunotherapy. Small, 2308639. DOI

Reda, M.; Ngamcherdtrakul, W.; Wang, R.; Crumrine, N.; Baker, C.; Wallstrum, A.; Saito, J.; White, N.; Yantasee, W., Abstract 5119: Nano-immunotherapy targeting PD-L1, PLK1, and TLR9 for treatment of non-small cell lung cancer. Cancer Research 2023, 83 (7_Supplement), 5119-5119. DOI 10.1158/1538-7445.Am2023-5119.

Ngamcherdtrakul, W.; Reda, M.; Baker, C.; Crumrine, N.; Wang, R.; Wallstrum, A.; White, N.; Saito, J.; Zaidan, H.; Rehwaldt, J.; Nelson, M.; Gray, J.; Yantasee, W., Abstract 3229: Triggering anti-tumor immune response with a nanotherapeutic that targets TLR9 and STAT3 pathways. Cancer Research 2023, 83 (7_Supplement), 3229-3229. DOI 10.1158/1538-7445.Am2023-3229.


Reda, M., Ngamcherdtrakul, W., Nelson, M.A., Siriwon, N., Wang, R., Zaidan, H.Y., Bejan, D. S., Reda, S., Hoang, N.H., Crumrine, N.A., Rehwaldt, J.P.C., Bindal, A., Mills, G.B., Gray, J.W., Yantasee, W. Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment. Nat Commun 13, 4261 (2022). View Online

Ngamcherdtrakul, W., Bejan, D. S., Cruz-Muñoz, W., Reda, M., Zaidan, H.Y., Siriwon, N., Marshall, S., Wang, R., Nelson, M.A., Rehwaldt, J.P.C., Gray, J.W., Hynynen, K., Yantasee, W. Targeted Nanoparticle for Co-delivery of HER2 siRNA and a Taxane to Mirror the Standard Treatment of HER2+ Breast Cancer: Efficacy in Breast Tumor and Brain Metastasis. Small, 2022., View Online, View cover


Therapeutic constructs for co-delivery of mitotic kinase inhibitor and immune checkpoint inhibitor
W Yantasee, R Moataz, W Ngamcherdtrakul
US Patent App. 17/023,311.

Immunotherapeutic constructs and methods of their use
W Yantasee, L Amanda, W Ngamcherdtrakul, R Moataz
US Patent App. 16/999,948

Ngamcherdtrakul, W., Reda, M., Nelson, M.A., Wang, R., Zaidan, H.Y., Bejan, D.S., Hoang, N.H., Lane, R.S., Luoh, S., Leachman, S.A., Mills, G.B., Gray, J.W., Lund, A.W., Yantasee, W. In situ tumor vaccination with nanoparticle co-delivering CpG and STAT3 siRNA to effectively induce whole-body antitumor immune response. Advanced Materials, 2021, 33 (31), 2170244, View Online, View cover

Nelson, M.A., Ngamcherdtrakul, W., Luoh, S., Yantasee, W. Prognostic and therapeutic role of tumor-infiltrating lymphocyte subtypes in breast cancer. Cancer Metastasis and Reviews, 2021, 40, 519–536. View Online

Salve R, Kumar P, Ngamcherdtrakul W, Gajbhiye V, Yantasee W. Stimuli-responsive mesoporous silica nanoparticles: A custom-tailored next generation approach in cargo delivery. Mater Sci Eng C Mater Biol Appl. 2021 May;124:112084. | View Online


Reda M, Bagley AF, Zaidan HY, Yantasee W. Augmenting the therapeutic window of radiotherapy: A perspective on molecularly targeted therapies and nanomaterials. Radiother Oncol. 2020 Sep;150:225-235. | View Online

Jan Schuemann, Alexander Bagley, Ross Berbeco, et al. Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions, Phys Med Biol. 2020 Oct 22;65(21):21RM02. | View Online


Ngamcherdtrakul, W., Yantasee, W. siRNA therapeutics for breast cancer: recent efforts in targeting metastasis, drug resistance, and immune evasion. Translational Research. 2019, 214: 105-120. | View Online

Reda, M., Ngamcherdtrakul, W., Gu, S., Bejan, D.S., Siriwon, N., Gray, J.W., Yantasee, W. PLK1 and EGFR targeted nanoparticle as a radiation sensitizer for non-small cell lung cancer. Cancer Letters. 2019, 467:9-18. | View Online

Worapol Ngamcherdtrakul, Thanapon Sangvanich, Shaun Goodyear, Moataz Reda, Shenda Gu, David J. Castro, Primana Punnakitikashem, and Wassana Yantasee. Lanthanide-Loaded Nanoparticles as Potential Fluorescent and Mass Probes for High-Content Protein Analysis, Bioengineering. 2019, 6(1), 23. | View online

Ngamcherdtrakul, W., Morry, J., Sangvanich, T., Reda, M., Bejan, D.S., Fryxell, G.E., Yantasee, W. Removal of a gadolinium based contrast agent by a novel sorbent hemoperfusion in a chronic kidney disease (CKD) rodent model. Scientific Reports. 2019, 9:709, 1-9. | View online

Yantasee, W., Fryxell, G. E., Pattamakomsan, K., Sangvanich, T., Wiacek, R.J., Busche, B., Addleman, R.S., Timchalk, C., Ngamcherdtrakul, W., Siriwon, N. Selective capture of radionuclides (U, Pu, Th, Am and Co) using functional nanoporous sorbents. 2019, 366, 677–683. | View online 


    Gu, S., Ngamcherdtrakul, W., Reda, M., Hu, Z., Gray, J.W., Yantasee, W. Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment. PLoS One. 2018, 13(6):e0198141. | View PDF 

    Ngamcherdtrakul, W., Sangvanich, T., Reda, M., Gu, S., Bejan, D., Yantasee, W. Lyophilization and Stability of Antibody Conjugated Mesoporous Silica Nanoparticle with Cationic Polymer and PEG for siRNA delivery. International Journal of Nanomedicine. 2018, 13, 4015–4027. | View Online


    Morry, J., Ngamcherdtrakul, W., Gu, S., Reda, M., Castro, D.J., Sangvanich, T., Gray, J.W., Yantasee, W. Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform. Molecular Cancer Therapeutics, 2017, 16(4):763-72. | View PDF


    Morry, J., Ngamcherdtrakul, W., Yantasee, W. Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles. Redox Biology, 2016, 11:240-253. | View PDF

    Ngamcherdtrakul, W., Castro, D.J., Gu, S., Morry, J., Reda, M., Gray, J.W., Yantasee, W. Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment. Cancer Treatment Reviews, 2016, 45:19-29. | View Abstract

    Gu, S., Hu, Z., Ngamcherdtrakul, W., Castro, D.J., Morry, J., Reda, M., Gray, J.W., Yantasee, W. Therapeutic siRNA for drug-resistant HER2-positive breast cancer. Oncotarget, 2016, 7(12): 14727-14741. | View PDF


    Morry, J., Ngamcherdtrakul, W., Gu, S., Goodyear. S., Castro, D., Reda, M., Sangvanich, T., Yantasee, W. Dermal delivery of HSP47 siRNA with NOX4-modulating mesoporous silica-based nanoparticles for treating fibrosis. Biomaterials2015, 66:41-52. | View PDF

    Ngamcherdtrakul, W., Morry, J., Gu, S., Castro, D. J., Goodyear, S. M., Sangvanich, T., Reda, M. M., Lee, R., Mihelic, S. A., Beckman, B. L., Hu, Z., Gray, J. W., Yantasee, W. Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted siRNA Delivery to HER2+ Breast Cancer. Advanced Functional Materials2015, 25(18), 2646-2659.  View Cover | View PDF


    Sangvanich, T., Ngamcherdtrakul, W., Lee, R., Morry, J., Castro, D., Fryxell, G. E.,  Yantasee, W.  Nanoporous Sorbent Material as an Oral Phosphate Binder and for Aqueous Phosphate, Chromate, and Arsenate Removal. J Nanomed Nanotechnol, 2014, 5:4. View PDF

    Sangvanich, T., Morry, J., Fox, C., Ngamcherdtrakul, W., Goodyear, S., Castro, D., Fryxell, G.E., Addleman, R.S., Summers, A.O., & Yantasee, W. Novel Oral Detoxification of Mercury, Cadmium, And Lead with Thiol-Modified Nanoporous Silica. ACS Applied Materials & Interfaces, 2014, 6 (8), 5483-5493. View PDF


    Yantasee, W, W. Chouyyok, RJ Wiacek, JA Creim, RS Addleman, GE Fryxell, CE Timchalk, Functionalized nanoporous silica for oral chelation therapy of a board range of radionuclides. Chapter 14 in Environmental Applications of Nanomaterials: Synthesis, Sorbents and Sensors, GE Fryxell and G Cao (eds), 2nd Edition, Imperial College Press, London, United Kingdom, 2012, pp. 369-379.

    Davidson, J. D., Wiacek, R. J., Burton, S., Li, X. S., Fryxell, G. E., Addleman, R. S., Yantasee, W., Sangvanich, T. & Pattamakomsan, K. Improved deposition and deprotection of silane tethered 3,4 hydroxypyridinone (HOPO) ligands on functionalized nanoporous silica. Inorganic Chemistry Communications2012, 18(0), 92-96. View PDF


    Yantasee, W., Rutledge, R. D., Chouyyok, W., Sukwarotwat, V., Orr, G., Warner, C. L., Warner, M. G., Fryxell, G. E., Wiacek, R. J., Timchalk, C., & Addleman, R. S. Functionalized Nanoporous Silica for the Removal of Heavy Metals from Biological Systems: Adsorption and Application. ACS Applied Materials & Interfaces2010, 2 (10), 2749-2758. View Cover | View PDF

    Yantasee, W., Fryxell, G.E., Porter, G.A., Pattamakomsan, K., Sukwarotwat, V., Chouyyok, W., Koonsiripaiboon, V., Xu, J., & Raymond, K.N. Novel Sorbents for Removal of Gadolinium-Based Contrast Agents in Sorbent Dialysis and Hemoperfusion: Preventive Approaches to Nephrogenic Systemic Fibrosis (NSF). (Feature article.) Nanomedicine: NBM2010, 6: 1-8. View Cover | View PDF

    Chouyyok, W., Wiacek, R.J., Pattamakomsan, K., Sangvanich, T., Grudzien, R.M., Fryxell, G.E., & Yantasee, W. Phosphate removal by anion binding on functionalized nanoporous sorbents. Environ. Sci. Technol2010, 44(8):3073-3078. View PDF

    Samuels, W., LaFemina, N., Sukwarotwat, V., Yantasee, W., & Fryxell, G.E. Chloromethylated activated carbon: A useful new synthon for making a novel class of sorbents for heavy metal separations, Sep. Sci. Technol2010, 45 (2): 288-235. View PDF

    Warner, C. L., Addleman, R.S., Cinson, A. D., Droubay, T. C., Engelhard, M. H., Nash, M. A., Yantasee, W. & Warner, M. G. High-Performance, Superparamagnetic, Nanoparticle– Based Heavy Metal Sorbents for Removal of Contaminants from Natural Waters. ChemSusChem2010, 3 (6): 749–757. View Cover | View PDF

    Sangvanich, T., Sukwarotwat, V., Wiacek, R.J., Grudzien, R.M., Fryxell, G.E., Addleman, R.S., Timchalk, C.& Yantasee, W. Selective Capture of Cesium and Thallium from Natural Waters and Simulated Wastes with Copper Ferrocyanide Functionalized Mesoporous Silica, Journal of Hazardous Materials2010, 182: 225-231. View PDF

    Yantasee, W., Sangvanich, T., Creim, J.A., Pattamakomsan, K., Wiacek, R.J., Fryxell, G.E., Addleman, R.S., & Timchalk,C., Functional sorbents for selective capture of plutonium, americium, uranium, and thorium in blood, Health Physics J (special issue), 2010, 99 (3): 413-419. View PDF

    Timchalk, C., Creim, J.A., Sukwarotwat, V., Wiacek, R., Addleman, S., Fryxell, G.E., & Yantasee, W. In Vitro and In Vivo Evaluation of a Novel Ferrocyanide Functionalized Nanopourous Silica Decorporation Agent for Cesium (Cs) in Rats, Health Physics J (special issue), 2010, 99 (3): 420-429. View PDF

    Chouyyok, W., Shin, Y., Davidson, J., Samuels, W.D., LaFemina N.H., Rutledge, R.D., Fryxell, G.E., Sangvanich, T. & Yantasee, W. Selective removal of copper (II) from natural waters by nanoporous sorbents functionalized with chelating diamines. Environ. Sci. Technol.2010, 44 (16): 6390-6395. View PDF

    Warner, M.G., Warner, C.L., Addleman, R.S., & Yantasee, W. Magnetic Nanomaterials for Environmental Sensing. In Magnetic Nanomaterials: NmLS-Series, vol. 4, Wiley-VCH, 2010.

    Addleman, R.S., Yantasee, W., Fryxell, G.E., Warner, M.G., Fontenot, S.A., Johnson, D.W., Bays, J.T., Warner, C.L. Nanostructured materials for selective collection of trace-level metals from aqueous systems. DT Pierce, JX Zhao (eds). In Trace Analysis with Nanomaterials, 2010.


    Yantasee, W., Fryxell, G.E., Addleman, R.S., Wiacek, R.J., Koonsiripaiboon, V., Pattamakomsan, K., Sukwarotwat, V., Xu, J., & Raymond, K.N. Selective Removal of Lanthanides from Natural Waters, Acidic Streams and Dialysate, J. Hazard. Mater.2009, 168, 1233. View PDF

    Chouyyok, W., Yantasee, W., Shin, Y., Grudzien, R.M., & Fryxell, G.E. Transition metal ion capture using functional mesoporous carbon made with 1,10-Phenathroline, Inorg. Chem. Commun.2009, 12:1099. View PDF

    Busche, B., Wiacek, R., Davidson, J., Koonsiripaiboon, V., Yantasee, W., Addleman, R.S., & Fryxell, G.E. Synthesis of nanoporous iminodiacetic acid sorbents for binding transition metals, Inorg. Chem. Commun.2009, 12, 312. View PDF


    Yantasee, W., Charnhattakorn, B., Fryxell, G.E., Lin, Y., Timchalk, C., & Addleman, R.S. Detection of Cd, Pb, and Cu in Non-Pretreated Natural Waters and Urine with Thiol Functionalized Mesoporous Silica and Nafion Composite Electrodes. Anal. Chim. Acta2008. 620:55–63. View PDF

    Yantasee, W., Hongsirikarn, K., Warner, C.L., Choi, D., Sangvanich, T., Toloczko, M.B., Warner, M.G., Fryxell, G.E., Addleman R.S., & Timchalk, C. Direct detection of Pb in urine and Cd, Pb, Cu, and Ag in natural waters using electrochemical sensors immobilized with DMSA functionalized magnetic nanoparticles. Analyst2008, 133: 348 – 355. View PDF

    Harrer, B.J., Yantasee, W., & Fryxell, G.E. Sensitive nanomaterials-based detection system rapidly measure heavy metals in liquids, MRS Bulletin2008, 33:820. View PDF

    Carter, T.G., Yantasee, W., Sangvanich, T., Fryxell, G.E., Johnson, D.W., & Addleman, R.S. New Functional Materials for Heavy Metal Sorption: Supramolecular Attachment of Thiols to Mesoporous Silica Substrates, Chemical Communications2008, 5583-5585. View PDF


    Yantasee, W., Warner, C.L, Sangvanich, T., Addleman, R.S., Carter, T.G., Wiacek, R.J., Fryxell, G.E., Timchalk, C., & Warner, M.G. Removal of Heavy Metals from Aqueous Systems with Thiol Functionalized Superparamagnetic Nanoparticles. Environ. Sci. Technol. 2007, 41(14): 5114-5119. View PDF

    Yantasee, W., Timchalk, C., & Lin, Y. Microanalyzer for Biomonitoring of Lead (Pb) in Blood and Urine. Anal Bioanal Chem2007, 387(1):335-341. View PDF

    Yantasee, W., Lin, Y., & Fryxell, G.E. Electrochemical sensors based on nanomaterials for environmental monitoring. Chapter 15 in Environmental Applications of Nanomaterials: Synthesis, Sorbents and Sensors, ed. Glen E. Fryxell and Guozhong Cao, Imperial College Press, London, United Kingdom. 2007. pp. 401-438.

    Yantasee, W., Lin,Y., Hongsirikarn, K., Fryxell, G.E., Addleman, R.S., & Timchalk, C. Electrochemical Sensors for the Detection of Lead and Other Toxic Heavy Metals: The Next Generation of Personal Exposure Biomonitors. Environ. Health Perspect. 2007, 115(12):1683-1690. View PDF


    Yantasee, W., Fryxell, G.E., & Lin, Y. Voltammetric Analysis of Europium at Screen-Printed Electrodes Modified with Salicylamide Self-Assembled on Mesoporous Silica. Analyst2006, 131(12):1342-1346. View PDF

    Timchalk, C., Lin, Y., Weitz, K.K., Wu, H., Moore, D.A., & Yantasee, W. Disposition of Lead (Pb) in Saliva and Blood of Sprague-Dawley Rats Following a Single or Repeated Oral Exposure to Pb-Acetate. Toxicology. 2006, 222:86-94. View PDF


    Yantasee, W., Timchalk, C., Weitz, K.K., Moore, D.A., & Lin, Y. Optimization of a Portable Microanalytical System to Reduce Electrode Fouling from Proteins Associated with Biomonitoring of Lead (Pb) in Saliva, Talanta2005, 67 617–624. View PDF

    Yantasee, W., Timchalk, C., Fryxell, G.E., Dockendorff, B.P., & Lin, Y. Automated portable analyzer for lead (II) based on sequential flow injection and nanostructured electrochemical sensors, Talanta2005, 68(2):256-261. View PDF

    Yantasee, W., Deibler, L.A., Fryxell, G.E., Timchalk, C., & Lin, Y. Screen-Printed Electrodes Modified with Functionalized Mesoporous Silica for Voltammetric Analysis of Toxic Metal Ions, Electrochemistry Communications2005, 7(11):1170-1176. View PDF

    Yantasee, W., Fryxell, G.E., Lin, Y., Wu, H., Raymond, K.N., & Xu, J. Hydroxypyridinone (HOPO) functionalized self-assembled monolayers on nanoporous silica for sequestering lanthanide cations, J. Nanosci. Nanotech. 2005, 5(4):526-529. View PDF

    Yantasee, W., Fryxell, G.E., Conner, M.M., & Lin, Y. Nanostructured Electrochemical Sensors Based on Functionalized Nanoporous Silica for Voltammetric Analysis of Lead, Mercury and Copper, J. Nanosci. Nanotech.2005, 5, 1537-1540.

    Tu, Y., Lin, Y., Yantasee, W., & Ren, Z. Carbon nanotubes based nanoelectrode array: fabrication, evaluation and application in voltammetric analysis. Electroanalysis, (Invited, Carbon Nanotubes special issue), 2005, 17(1):79-84. View PDF

    Incorporation of hydroxypyridinone (HOPO) ligands into self-Assembled monolayers on mesoporous supports (SAMMS) for selective actinide sequestration, An invited paper, special issue on Nanoscale Environmental Science and Technology (NES&T), Environ. Sci. Technol. 2005, 39(5):1332-1337. View PDF

    Wang, Z., Zachara, J., Yantassee, W., Gassman, P.L., Joly, A.G., & Catalano, J. Fluorescence Spectroscopy of U(VI)-Silicates and U(VI)-contaminated Hanford sediment, Geochim. Cosmochim. Acta2005, 69:1391-1403. View PDF

    Wang Z, AR Felmy, Y Xia, O Qafoku, Yantasee, W, and HM Cho. Complexation of Cm(III)/Eu(III) with Silicate in Basic Solutions. Radiochimica Acta2005, 93(12):741-748.


    Yantasee, W., Lin, Y., Fryxell, G.E., & Wang, Z. Carbon paste electrode modified with carbamoylphosphonic acid functionalized mesoporous silica: a new mercury-free sensor for uranium(VI) detection. Electroanal.2004, 16(10):870-873. View PDF

    Yantasee, W., Lin, Y., Alford, K.L., Busche, B.J., Fryxell, G.E., & Engelhard, M. Electrophilic aromatic substitutions of amine and sulfonate onto fine-grained activated carbon for aqueous-phase metal ion removal. Sep. Sci. Technol.2004, 39(14) 3263-3279. View PDF

    Yantasee, W., Lin, Y., Alford, K.L., Busche, B.J., Fryxell, G.E., & Johnson C.D. Selective removal of copper(II) from aqueous solutions using fine-grained activated carbon functionalized with amine. Ind. Eng. Chem. Res.2004, 43:2759-2764. View PDF

    Wang, Z., Zachara, J., Yantassee, W., Gassman, P. L., Liu, C. X., & Joly, A. G. Cryogenic laser induced fluorescence characterization of U(VI) in Hanford vadose zone pore waters. Environ. Sci. Technol.2004, 38:5591-5597. View PDF

    Lin, Y., Yantasee, W., & Fryxell, G.E. Electrochemical sensors based on functionalized nanoporous silica, Dekker Encyclopedia of Nanoscience and Nanotechnology. 2004, 1051-1062. Marcel Dekker, New York.

    Lin, Y., Yantasee, W., Lu, F., Wang, J., Musameh, M., Tu, Y., & Ren, Z. Biosensors based on carbon nanotubes, Dekker Encyclopedia of Nanoscience and Nanotechnology2004, 361-374. Marcel Dekker, New York.

    Lin,Y.; Yantasee, W; Wang, J.; Musameh, M. Carbon Nanotubes (CNTs) for the development of electrochemical biosensors, Invited article, Frontiers in Biosci.2004, 10(1):492-505. View PDF


    Yantasee, W., Lin, Y., Li, X., Fryxell, G.E., Zemanian, T.S., & Viswanathan, V.V. Nanoengineered electrochemical sensor based on mesoporous silica thin-film functionalized with thiol-terminated monolayer. Analyst2003, 128 (7): 899-904. View PDF

    Yantasee, W., Lin, Y., Zemanian, T.S., & Fryxell, G.E. Voltammetric detection of lead(II) and mercury(II) using a carbon paste electrode modified with thiol self-assembled monolayer on mesoporous silica (SAMMS). Analyst2003, 128 (5): 467-472. View PDF

    Yantasee, W., Lin, Y., Fryxell, G.E., & Busche, B.J. Simultaneous detection of cadmium(II), copper(II), and lead(II) using a carbon paste electrode modified with carbamoylphosphonic acid self-assembled monolayer on mesoporous silica (SAMMS). Anal.Chim. Acta. 2003, 502, 207-212. View PDF

    Yantasee, W., Lin, Y., Fryxell, G.E., Busche, B.J., & Birnbaum, J.C. Removal of heavy metals from aqueous solution using novel nanoengineered sorbents: self-assembled carbamoylphosphonic acids on mesoporous silica. Sep. Sci. Technol. 2003, 38 (15): 3809-3825. View PDF


    Yantasee, W., & Rorrer G.L. Comparison of ion exchange and Donnan equilibrium models for the pH-dependent adsorption of sodium and calcium ions onto kraft wood pulp fibers. J Wood Chem Technol2002, 22 (2-3), 157-185. View PDF​​​​​