Myelin repair study by Dr. Meredith Hartley selected as 2019 Postdoctoral Paper of the Year

Meredith Hartley, Ph.D. (left), and Tom Scanlan, Ph.D. (OHSU/Kristyna Wentz-Graff)
Meredith Hartley, Ph.D. (left), and Tom Scanlan, Ph.D. (OHSU/Kristyna Wentz-Graff)

The OHSU School of Medicine Alumni Council selected a study by first author Meredith Hartley, Ph.D., to receive its 2019 School of Medicine Alumni Association Postdoctoral Paper of the Year Award. Read more.

Two basic science departments to join

SoM leverages expertise, technology and fresh investment to form new, expanded department

Dean Sharon Anderson approved a proposal to combine two basic science departments in the OHSU School of Medicine to form a new, expanded department starting July 1.

The Department of Biochemistry and Molecular Biology and the Department of Physiology and Pharmacology will join together to leverage faculty specialties and technology. Read more.

Members of the Department of Biochemistry and Molecular Biology and the Department of Physiology and Pharmacology

Highlighted publication: Valiyaveetil lab

"Investigation of the allosteric coupling mechanism in a glutamate transporter homolog via unnatural amino acid mutagenesis"

Glutamate transporters harness ionic gradients for the concentrative uptake of glutamate. Normal function of glutamate transporters is required for rapid removal of glutamate from the synapse, which is required for efficient neurotransmission and for preventing excitotoxicity. A key question in glutamate transporters is the mechanism by which the ionic gradient is coupled to glutamate uptake. Recent studies from the Valiyaveetil lab used unnatural amino acid mutagenesis to probe this mechanism and their studies now provide a molecular sequence for the events in the coupled binding of sodium and substrate to the glutamate transporter.