Baconguis Lab

Assistant Scientist and Principal Investigator: Isabelle Baconguis

Current lab members

Arpita Bharadwaj, PhD

Arpita Bharadwaj

Senior Research Associate

Email: bharadwa@ohsu.edu

Arpita graduated from Creighton University School of Medicine with a Ph.D. in Immunology. She investigated the phenotype of dendritic cells in the lungs after treatment of bronchial asthma with Flt3 ligand. Arpita worked as a postdoctoral fellow at Mt. Sinai Medical Center where her research involved identifying mechanisms that result in factor IX tolerance following gene therapy with adeno-associated viral serotype-1 vector. In her second postdoctoral fellowship, in the laboratory of Justine Smith at Oregon Health & Science University, she studied the role of immune cells in the inflammation of the eyes. She joined the Baconguis lab in February 2014 to work on the structure and function of sodium channels.

Kim Hartfield, PhD

Kimberly Hartfield

Postdoctoral Fellow

Email: hartfiel@ohsu.edu

Kimberly was awarded a Ph.D. from The Scripps Research Institute for her work in structural biology and biophysics. Her dissertation research focused on crystallographic characterization of redox-active metalloproteins cytochrome P450 and cytochrome c oxidase under the supervision of Dr. C. David Stout. She then engaged in postdoctoral research at the Vollum Institute in the laboratory of Dr. Matt Whorton, studying the structure of the secondary-messenger signaling protein adenylyl cyclase using single-particle cryo-electron microscopy. She joined the Baconguis lab in 2020, where she works on structural–functional characterization of nucleotide-sugar transporters.

Alex Houser

Alexandra Houser

Graduate Student

Email: housera@ohsu.edu

Alex received her B.S. in Molecular, Cell and Developmental Biology at the University of California Santa Cruz. While there she studied the autoregulation of the motor protein Kinesin under the mentorship of Dr. William Saxton. Following her undergraduate work, she spent two years working in Dr. David Bilder’s lab at the University of California Berkeley. Her research focused on the glycosylation of the Tumor Necrosis Factor Receptor in a Drosophila melanogaster tumor model. Alex started in the Neuroscience Graduate Program at OHSU in September 2018. She joined the Baconguis Lab in September 2019 and is focusing on ENaC in the nervous system for her doctoral thesis.

Contact information

Lab phone number

503-494-6480

Lab location

Vollum Room 1427 

Faculty support

Teresa Newton

Grants/Contracts Coordinator

Email: newtont@ohsu.edu

Phone: 503-494-5458

Mailing address

Isabelle Baconguis Lab

Vollum Institute, OHSU

3181 SW Sam Jackson Park Rd.

Mail code L474

Portland, OR 97239-3098

Shipping address

Isabelle Baconguis Lab

Vollum Institute, OHSU

3181 SW Sam Jackson Park Rd.

Dock 4, Vollum Rm. 1427

Portland, OR 97239-3098

Vollum Institute

3232 SW Research Drive
Portland, OR 97239

Name Years in Lab Lab Position Current Position
Sigrid Noreng 2015–2020 Graduate Student Scientist, Septerna
Maansi Singh 2019-2020 Volunteer Undergraduate Student, UCLA
James Cahill 2020-2023 Research Assistant Medical Student, OHSU