Vaccine and Gene Therapy Institute Faculty and Research

VGTI Leadership

Jake Estes Headshot

Jacob D. Estes, Ph.D.

Director

About our research

Estes Lab

Louis Picker Headshot

Louis Picker, M.D.

Associate Director

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Picker Lab

VGTI Faculty

Patrizia Caposio Headshot

Patrizia Caposio, Ph.D.
Associate Professor

About our research
Caposio Lab

Research interests:
CMV pathogenesis, vascular diseases, and angiogenesis

Vic Defilippis Headshot

Victor DeFilippis, Ph.D.
Professor

About our research
DeFilippis Lab

Research interests:
Activation and evasion of innate immune responses by viral pathogens

Klaus Frueh headshot

Klaus Frueh, Ph.D.
Professor

About our research
Frueh Lab

Research interests:
HHV8 virology and pathobiology, functional genomics, host pathogen interaction: particularly viral Immune modulation Works with the following viral families: Herpesviruses (cytomegalovirus, Kaposi’s sarcoma associated virus), Poxviruses (Cowpox, Monkeypox), Flaviviruses (West Nile Virus, Dengue Virus)

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Meaghan Hancock, Ph.D.
Assistant Professor

About our research
Hancock Lab / Nelson Lab

Research interests:
Studying the roles of human cytomegalovirus (CMV) miRNAs in modulating host cellular signaling pathways

Scott Hansen Headshot

Scott Hansen, Ph.D.
Professor

About our research
Hansen Lab

Research interests:
HIV pathogenesis and vaccine development

Alec Hirsch headshot

Alec Hirsch, Ph.D.
Associate Professor

About our research
Hirsch Lab

Research interests:
Virus-host cell interactions

Daniel Malouli Headshot

Daniel Malouli, Ph.D.
Assistant Professor

About our research

Research interests:
Cytomegalovirus genomics, determinants of species specificity and evolution; BAC recombineering and vector construction, Vaccine development; non-human primate in vivo models. 

Afam Okoye headshot

Afam Okoye, Ph.D.
Professor

About our research
Okoye Lab

Research interests:
Viral pathogenesis, T cell homeostasis, Immunological aging

Rebecca Skalsky headshot

Rebecca Skalsky, Ph.D.
Associate Professor 

About our research
Skalsky Lab

Research interests:
Non-coding RNAs (i.e. microRNAs) in viral pathogenesis, DNA tumor virus biology (i.e. gamma-herpesviruses)

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Daniel Streblow, Ph.D.
Professor

About our research
Streblow Lab

Research interests:
CMV pathogenesis and transplantation

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Brandon Wilder, Ph.D.
Associate Professor

About our research
Wilder Lab

Research interests:
The Wilder lab is focused on understanding how our immune system can fight malaria, and how we can use this information to make an effective vaccine suitable for widespread use and elimination of this ancient disease

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Scott W. Wong, Ph.D.
Professor

About our research
Wong Lab

Research interests:
Viral pathogenesis and therapeutic development

Emily Voigt headshot

Emily Voigt, Ph.D.
Associate Professor

About our research
Voigt Lab

Research interests:
Innovation of nucleic acid-based vaccine platforms for global health use. Translational infectious disease and cancer vaccine development, preclinical, and clinical testing. Vaccine adjuvant and delivery system discovery.

Research Assistant Professor

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Kathleen Busman-Sahay, Ph.D.
Assistant Professor

About our research

Research interests:

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Nicole Diggins, Ph.D.
Assistant Professor

About our research

Research interests:

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Caralyn Labriola, Ph.D.
Assistant Professor

About our research

Research interests:

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Julie Mitchell, Ph.D.
Assistant Professor

About our research

Research interests:
My work focuses on how children respond differently to vaccines and infections than adults, and how we can target unique aspects of the pediatric immune system to provide children better protection against disease.

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Gaby Samayoa Reyes, Ph.D.
Assistant Professor

About our research

Research interests:

Affiliate Faculty

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Michael Axthelm, DVM, Ph.D.
Associate Professor, Division of Pathobiology and Immunology, ONPRC

About our research

Research interests:
NPH models for Aids research, virology and human viral diseases

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Benjamin Burwitz, Ph.D.
Associate Professor, Division of Pathobiology and Immunology, ONPRC

About our research

Research Interest:

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Benjamin N. Bimber, Ph.D.
Assistant Professor, Oregon National Primate Research Center

About our research

Research interests:
HIV/TB/Malaria pathogenesis, Bioinformatics, Immunogenetics

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Marcel E. Curlin, M.D.
Associate Professor of Medicine, Division of Infectious diseases, School of Medicine
Joint Appointment: Associate Professor at VGTI

About our research

Clinical Research Interest:
HIV Vaccine research, emerging infectious diseases and development of international collaborative research initiatives between OHSU and partners in Southeast Asia

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Nancy Haigwood, Ph.D.
Professor, Division of Pathobiology and Immunology, ONPRC

About our research

Research interest:
HIV humoral immunity and pathogenesis

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Morgan Hakki, M.D.
Professor of Medicine, Division of Infectious Diseases, School of Medicine, Division Head, Medicine, Division of Infectious Diseases, School of Medicine
Affiliate Faculty Vaccine & Gene Therapy Institute, OHSU

About our research

Research interest:
Infections in the immunocompromised host (non-HIV) Cytomegalovirus, Pseudomonas aeruginosa

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Ann J. Hessell, Ph.D.
Professor & Division Head, Division of Pathobiology and Immunology, ONPRC

About our research

Research interests:
HIV humoral immunity and pathogenesis

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Jon M. Jacobs, Ph.D.
Staff Scientist Level V, Environmental & Molecular Sciences Division. PNNL
Team lead Cell Signaling and Communications Team within Functional & Systems Biology Group. PNNL
Affiliate Faculty Vaccine & Gene Therapy Institute, OHSU

About our research

Research Interest:

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Christina Lancioni, MD
Professor, Department of Pediatrics, Division of Infectious Diseases, Department of Medicine, School of Medicine
Affiliate Faculty Vaccine & Gene Therapy Institute, OHSU

About our research

Research interests:
Pediatric Tuberculosis; Perinatal HIV infection & exposure; Nutrition & Immunity

John T. Melchior headshot

John Trevvett Melchior, Ph.D.
Scientist IV, Molecular Structure and Function Team Lead, Molecular Structure, Function & Design, Biological Sciences Division, PNNL
Affiliate Assistant Professor, Department of Neurology, OHSU
Affiliate Faculty Vaccine & Gene Therapy Institute, OHSU
Visiting Scholar, Department of Pathology and Laboratory Medicine, University of Cincinnati

About our research

Research interests:

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Bill Messer, Ph.D.
Associate Professor, Molecular Microbiology & Immunology, OHSU

About our research

Research Interest:

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David Peeler
Assistant Professor, Department of Bioengineering, University of Oregon
Affiliate Faculty Vaccine & Gene Therapy Institute, OHSU

About our research

Research Interest:

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Jonah Sacha Ph.D.
Professor, Division of Pathobiology and Immunology, ONPRC

About our research:

Research Interest:

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Aleksandra Sikora, Ph.D.
Professor, Department of Pharmaceutical Sciences, Oregon State University
Adjunct Associate Professor, Vaccine & Gene Therapy Institute, OHSU

About our research

Research interests:
Therapeutic interventions against gonorrhea.

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Fikadu G. Tafesse, PhD
Associate Professor, Molecular Microbiology & Immunology OHSU

About our research

Research Interest:
host-pathogen interactions

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Rachael Wolters, Ph.D.
Research Assistant Professor Division of Pathobiology and Immunology ONPRC

About our research

Research Interest:

Previous VGTI Members

Jeremy Smedley, DVM, MS, DACLAM
Professor and Head of ONPRC Infectious Disease Resource

Ashlee Moses, Ph.D.
Professor