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The Vaccine and Gene Therapy Institute at Oregon Health & Science University has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. Learn more

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Recent publications

Antiviral Res. June 24, 2024
KDM5A/B contribute to HIV-1 latent infection and survival of HIV-1 infected cells

PLoS Pathog. June 17, 2024
MicroRNA-focused CRISPR/Cas9 screen identifies miR-142 as a key regulator of Epstein-Barr virus reactivation

ACS Infect Dis. June 11, 2024
3-Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance

Emerg Infect Dis. June 2024
Evaluating Humoral Immunity Elicited by XBB.1.5 Monovalent COVID-19 Vaccine

Elife. May 28, 2024
ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

bioRxiv. May 24, 2024
Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34+ hematopoietic progenitor cells and humanized mice

Malar J. May 23, 2024
Evaluation of naturally acquired immune responses against novel pre-erythrocytic Plasmodium vivax proteins in a low endemic malaria population located iun the Peruvian Amazon Basin

J Virol. May 22, 2024
Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection

bioRxiv. May 21, 2024
Viral and host network analysis of the human cytomegalovirus transcriptome in latency

bioRxiv. May 15, 2024
Trifunctional fatty acid derivatives demonstrate the impact of diazirine placement

Sci Adv. May 10, 2024
CD8+ T cell targeting of tumor antigens presented by HLA-E

Vaccine. April 11, 2024
Effectiveness of a bivalent mRNA vaccine dose against symptomatic SARS-CoV-2 infection among U.S. Healthcare personnel, September 2022-May 2023

PLoS Pathog. April 9, 2024
Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir

J Clin Invest. April 1, 2024
Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers

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Jay A Nelson Memorial Fund

Your Gift Brings Hope, Please support our mission in memory of Jay Nelson. Your generosity will help contribute to a healthier world, helping OHSU and Doernbecher Children's Hospital make that a world a reality Click to Donate

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COVID-19 Efforts - Building a COVID Testing Lab