Vaccine and Gene Therapy Institute (VGTI)

About us

The Vaccine and Gene Therapy Institute at Oregon Health & Science University has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. Learn more

Upcoming seminars

VGTI Seminar Series and Virology Journal Club is now streamed online. Please reach out to Chad (sixkille@ohsu.edu) if you would like a link to the live stream.

Recent publications

Trends Immunol. Mar 7^th, 2023
Programming cytomegalovirus as an HIV vaccine

mBio. Feb 28^th, 2023
Virology under the microscope-a call for rational discourse

mBio. Feb 22^nd, 2023
Advances in model systems for human Cytomegalovirus latency and reactivation

Nat Commun. Feb 22^nd, 2023
Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

Nat Med. Feb 20^th, 2023
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

JCI Insight. Feb 7^th, 2023
Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV

JCI Insight. Jan 23^rd, 2023
An extended interval between vaccination and infection enhances hybrid immunity against SARS-CoV-2 variants

Brain Behav Immun. Jan 19^th, 2023
Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease

View all publications

COVID-19 Efforts - Building a COVID Testing Lab