Welcome
The Vaccine and Gene Therapy Institute at Oregon Health & Science University has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. Learn more
VGTI Seminar Series
WORLD AIDS DAY SYMPOSIUM 2026
For more information and registration please head to www.worldaidsdaypdx2026.com
Recent publications
Nat Microbiol. Oct 19, 2026
SIV reservoir depletion and clearance from neonatal macaques following transient CCR5 depletion
AIDS Res Hum Retroviruses. Oct 7, 2026
Safety of Autologous Infusion of CER T Cells in Nonhuman Primates
Nat Commun. Oct 2, 2026
First-line dolutegravir/lamivudine in HIV-1 infection: lymph node penetration and reservoir decline in a randomized open-label clinical trial
Front Immunol. Oct 2, 2026
Effects of West Nile Virus on behavioral and cognitive performance, circadian body temperatures, cortical Aβ and p-tau pathology, and immune measures in human apoE and human amyloid precursor protein NL-G-F/human apoE mice
J Immunol. Oct 1, 2026
Preservation of MHC-Ia protective allele suppression of SIVmac239 in aged rhesus macaques
Cell Rep. Sep 30, 2026
Distinct phases of immune system programming during ART-suppressed immunodeficiency virus infection
Nat Biotechnol. Sep 28, 2026
Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing
Hum Gene Ther. Sep 11, 2026
Chimeric Antigen Receptor T Cell Targeting of Natural Killer Cells in Peripheral Blood and Tissues of Rhesus Macaques
PLoS Negl Trop Dis. Sep 8, 2026
Evaluation of a Zika virus-like particle-based vaccine in a highly penetrant non-human primate model of congenital infection
Curr Opin HIV AIDS. Sep 1, 2026
New horizons in HIV neuropathogenesis: thinking beyond the brain
Cell Rep. August 18, 2026
Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques
Nat Microbiol. August 10, 2026
Combination therapy with broadly neutralizing antibodies, antiretroviral therapy and CCR5 blockade limits viral reservoir seeding in infant macaque model of HIV
J Virol. July 27, 2026
The human cytomegalovirus chemokine binding protein UL22A is necessary for efficient reactivation from latency in CD34+ hematopoietic progenitor cells and humanized mice
Front. Immunol., July 21, 2026
T cell antigenic recognition sequencing (TAR-seq) enables precise characterization of vaccine-elicited cellular immunity ex vivo and in vivo
Curr Opin HIV AIDS. July 17, 2026
New Horizons in HIV neuropathogenesis: thinking beyond the brain
PLoS Negl Trop Dis. July 10, 2026
Infection of Rhesus Macaques with O’nyong-nyong virus UVRI-0804 recapitulates key aspects of human clinical disease
Transcription. July 2, 2026
MicroRNA expression and functions in viral infections
Nature. July 1, 2026
Identification of cross-stage, cross-species malaria CD8+ T cell antigens
Cell Rep. June 22, 2026
Addition of blood-stage antibody enhances anti-sporozoite antibody protection in a humanized mouse model of Plasmodium falciparum infection
J Virol. June 11, 2026
A newly developed eGFP-traceable recombinant rhesus lymphocryptovirus, a tool to study viral infection and replication in vitro and ex vivo, confirms gp350 as key for viral entry
Malar J. June 3, 2026
Development of novel Aotus nancymaae non-human primate model for the evaluation of Plasmondium vivax blood stage vaccines and immunoprophylactics
Ways to Give
Donate to Vaccine and Gene Therapy Institute.
VGTI offers two options and account to consider when donating that serve differing purposes:
The VGTI Support Foundation Fund
Gifts to the VGTI Support Foundation Fund provides vital support that allows us find cures for life threatening infectious diseases. These funds help us to have necessary resources and create and conduct innovative infectious disease research studies, leading to the development of vaccines and cures.
Donate to World AIDS Day 2026 Symposium
Together, Beyond HIV
Discovery, Compassion and Advocacy
Please help us support a great event
Saturday December 5th 2026
9 AM – 5 PM
Knight Cancer Research Building
Portland Oregon
www.ohsu.edu/worldaidsday
Donate.ohsufoundation.org/world-aids-day
The Jay Nelson Memorial Fund
Gifts to the Jay Nelson Memorial Fund supports providing education and learning opportunities for our current up and coming scientists with a focus on Herpesvirus.
Biographical Feature:
In memoriam Jay A. Nelson (1948–2024)
Your Gift Brings Hope, Please support our mission in memory of Jay Nelson. Your generosity will help support education and learning opportunities for our current up and coming scientists with a focus on Herpesvirus. Click to Donate
The VGTI Support Foundation Fund
Donate to VGTI
Your gifts help provide vital resources to conduct innovative research and more.
For more information and registration Please head to www.worldaidsdaypdx2026.com
COVID-19 Efforts - Building a COVID Testing Lab