Nuclear Magnetic Resonance (NMR) Core Facility
The NMR core facility has a Bruker 400 MHz Avance NEO NanoBay spectrometer, a powerful analytical tool routinely used for structural biology research. Housed in the Department of Chemical Physiology & Biochemistry, room number LBRB 670, the spectrometer is equipped with a 24 - position Sample Case automation system and a broad band iProbe.
The NMR instrument can be used for:
- Standard 1H/13C experiments (1D/2D) for monitoring reaction progress, checking purity and determining molecular structure and concentration.
- Advanced 2D NMR experiments (COSY, HSQC, HMBC, DEPT, NOESY/ROESY) for further structurale elucidation.
- Multi-nuclear NMR analysis (31P, 19F, 15N and other)
- Designing small molecules as probes of protein and cellular function
- Providing the foundation for the development of prototype therapeutic agents.
The instrument is available for “walk-on” use once the user is trained. Wilmad Precision NMR tubes model numbers 527-PP-7 (7”) and 527-PP-8 (8”) are recommended as lower quality tubes not only result in poor spectra by introducing large spinning bands and bad line shape, but also damage the Probe.
User training fee per hour
User run fee per hour of acquisition time