Members

Guna Dhandapani

Gunasekaran Dhandapani

Postdoctoral Fellow

dhandapa@ohsu.edu

Guna received a B.Tech. degree in Bioinformatics from Tamil Nadu Agricultural University, Coimbatore in 2012. He then completed an M.Sc. degree in Genomics at Madurai Kamaraj University, Madurai. While working at RMRC (ICMR), Port Blair, his research focused on characterization of recombinant proteases of Leptospira interrogans and identification of their role in invasion. Later, he joined the lab of Dr. Guy Patchornik at Ariel University, Israel in 2017. In his doctoral research, he worked on development of novel purification methods for IgGs, Fabs, and IgM antibodies. After receiving his Ph.D., Guna joined the Gouaux lab in Dec 2022 to develop new labeled mAbs, Fabs, and scFvs to study the molecular organization and function of chemical synapses.

Chengli Fang head shot image

Chengli Fang

Postdoctoral Fellow

fangch@ohsu.edu

Chengli received B.S. degree in Biological Engineering from Hunan University of Science and Technology, in 2016. Then, he joined Dr. Yu Zhang’s lab at Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, to study the mechanisms for RNA polymerase (RNAP) transcription, transcription initiation, and activation. After receiving his Ph.D., Chengli joined the Gouaux lab in June 2022 to study the structural and functional basis of neurotransmitter receptors.

April Goehring

April Goehring

Senior Research Associate

goehring@ohsu.edu

April Goehring earned a B.A. in Biochemistry from the University of Colorado-Boulder in 1993, and as an undergraduate participated in projects to characterize the regulation of MAP kinase kinase. In her graduate research, April’s work focused on the identification and characterization of proteins in yeast involved in polarized cell growth. She was granted a Ph.D. in Biochemistry in 2002 from the University of Oregon. Her postdoctoral training was carried out at the Vollum Institute where she studied anchored PKA signal transduction. Since joining the Gouaux lab in 2008, she has spent her time studying the molecular mechanisms of neurotransmitter transporters and receptors.

Hanbin Jeong

Hanbin Jeong

Postdoctoral Fellow

jeongh@ohsu.edu

Hanbin received his B.S. degree in Life Sciences from Ulsan National Institute of Science and Technology (UNIST), South Korea in 2014. He then joined the lab of Dr. Changwook Lee at UNIST. In his doctoral research, Hanbin mainly focused on the structural studies of membrane contact sites (MCSs) protein complex using X-ray crystallography. After receiving his Ph.D. degree in 2019, he continued his work in the Lee Lab. Hanbin joined the Gouaux Lab in 2021 to study the structure and function of transmembrane channel proteins using cryo-electron microscopy.

Hoyoung Kim

Hoyoung Kim

Postdoctoral Fellow

kimhoy@ohsu.edu

Hoyoung received his B.S. degree in Systems biology in 2015 at Yonsei University, Seoul, Republic of Korea and started a Ph.D. course in Structure Biology in the lab of Professor Hyun-Soo Cho at the same university. Hoyoung’s research focused on the studies of structure by XFEL, functional mechanism and discovery antagonist of human G-protein coupled Receptor (GPCR). After receiving his Ph.D. degree, Hoyoung joined Eric Gouaux’s lab in June 2024 to study the structure and function of neurotransmitter receptors by cryo-electron microscopy.

Junhoe Kim

Junhoe Kim

Postdoctoral Fellow

kimjunh@ohsu.edu

Junhoe received his B.S. degree in Life Sciences in 2011 at Korea University, Republic of Korea and started a Ph.D. course in Molecular Biology in the lab of Professor Hyun Kyu Song at the same university. His thesis focused on the studies of structure and function of human autophagy-related (ATG) proteins underlying autophagosome maturation mechanism. After earning his Ph.D. degree, Junhoe joined Eric Gouaux’s lab in the summer of 2019 to study the structure and function of neurotransmitter receptors.

Yaya Kiss head shot

Yaya Kiss

Research Assistant I

kissy@ohsu.edu

Yaya graduated from Oregon State University in 2025 with a bachelor of science in Biochemistry and Biophysics. During her time at OSU, she worked within the Electron Microscope Facility learning how to image on SEM/TEM and complete sample processing. She has since joined the Gouaux lab for the summer to learn more about the cryoFIB preparation process for tissues.

Aya Matsui

Aya Matsui

Senior Research Associate

matsuia@ohsu.edu

Aya received a B.S. degree in Neurobiology from the University of Washington in 2007. She joined the lab of Dr. John Williams at OHSU for her Ph.D. research, which investigated how activation of the mu-opioid receptor disinhibits the dopamine neuron and its modulation following chronic opioid treatment. Aya completed her postdoctoral training in the lab of Dr. Veronica Alvarez at the National Institute of Alcohol Abuse and Alcoholism (NIH), where she studied neuronal modulation following drugs of abuse, such as cocaine and alcohol. She joined the Gouaux lab in 2020 to study the structure and function of synaptic receptors.

Jumi Park

Jumi Park

Postdoctoral Fellow

parkjum@ohsu.edu

Jumi received a B.S degree in Life Sciences from Ulsan National Institute of Science and Technology, South Korea in 2016. She then joined Prof. Changwook Lee’s lab at the same university, focusing on the molecular mechanisms of membrane contact sites between organelles and DNA/RNA processing proteins. After earning her Ph.D., Jumi joined the Gouaux lab in April 2021 to investigate the structure and function of neurotransmitter receptors.

Damien Rasmussen

Damien Rasmussen

Postdoctoral Fellow

rasmussd@ohsu.edu

Damien completed his undergraduate degree at the University of Wisconsin-La Crosse in 2017. He then joined Nick Levinson’s laboratory at the University of Minnesota, where he used a variety of optical and magnetic resonance spectroscopies to study the allosteric regulatory mechanisms of the protein kinase BRAF. After earning his Ph.D., Damien joined the Gouaux lab in May 2024, where he is investigating the structural mechanisms of neurotransmitter transport using single particle cryo-EM.

Natalie Sheldon

Natalie Sheldon

Lab Manager

sheldonn@ohsu.edu

Natalie was born and raised in Oregon and earned a B.S. in Biology from Hope College in Holland, MI. While earning her degree she worked on the transporter system xc- in Leah Chase's lab. After graduation in 2006 she joined the Gouaux lab, and her primary role has been to do support work for the entire lab. Natalie also does the purchasing for the lab and tries her hardest to maintain some organization and cleanliness around the lab.

Jinwoo Shin head shot

Jinwoo Shin

Postdoctoral Fellow

shinji@ohsu.edu

Jinwoo received his B.S. degree in Life Sciences from Myongji University in South Korea in 2016. He then joined Dr. Yunje Cho’s lab at Pohang University of Science and Technology (POSTECH), where his research focused on the structural characterization of DNA repair proteins and G-protein coupled receptors (GPCRs) using X-ray crystallography and cryogenic electron microscopy. These studies revealed the molecular mechanisms by which these proteins play crucial roles in our body. He earned his Ph.D. by elucidating the constitutive activation mechanism of the orphan GPCR, GPR156. Following his Ph.D., Jinwoo joined Eric Gouaux’s lab in March 2025 to study the structural characterization of native proteins and cellular components in the neurosynaptic environment.

Cathy Spangler head shot

Cathy Spangler

Postdoctoral Fellow

andecath@ohsu.edu

Cathy received B.S. degrees in Chemistry and Biology from the University of North Carolina at Chapel Hill in 2016. She went on to conduct her graduate research at the same institution in the lab of Dr. Robert McGinty, where she used single particle cryo-electron microscopy to investigate how chromatin-interacting proteins bind to and enzymatically target specific sites on the nucleosome. After earning her PhD, Cathy joined the Gouaux lab in the Spring of 2022 and is exploring the structural and functional basis of neurotransmitter receptor misregulation in glioblastoma.

Dushyant Srivastava

Dushyant Srivastava

Postdoctoral Fellow

srivastd@ohsu.edu

Dushyant received his B.Sc. degree in 2011 and M.Sc. degree in 2013 in Zoology from University of Calcutta, India. He then joined the lab of Dr. Siddhartha Roy at CSIR-Indian Institute of Chemical Biology to pursue his doctoral research work in the field of chromatin biology where he pursued structural studies on histone chaperones and chromatin reader protein by X-ray crystallography. After receiving his Ph.D. in Biochemistry from University of Calcutta, India he joined Gouaux Lab in June 2022 to study the structural and functional aspects of neurotransmitter transporters. 

Gaoqi Weng

Gaoqi Weng

Postdoctoral Fellow

weng@ohsu.edu

Gaoqi received his B.S. in Pharmacy from Zhejiang University, China, in 2018. He then started his graduate studies in computer-aided drug design at Zhejiang University, under the supervision of Prof. Tingjun Hou. Gaoqi's research focused on the computational methodology study on protein-protein interactions and PROTACs. After receiving his Ph.D., Gaoqi joined the Gouaux Lab in November 2023 to study the molecular mechanism of transmembrane channel proteins using cryo-electron microscopy.

Former Members

  • Justus Wilke – Visiting Research Scholar (2024-2025)

    Current position: Postdoctoral Fellow, Charité-Universitätsmedizin Berlin, Germany

     
  • Chang Sun – Postdoctoral Fellow (2018-2025)

    Current position: Research Scientist, Li lab, Van Andel Institute

  • Makayla Freitas – Graduate Student (2020-2025)

    Current position: Postdoctoral Fellow, University of California San Francisco

  • Audrey Chinn – Student Worker (2021-2024)

    Current position: Graduate Student, Washington University in St. Louis

     
  • Sarah Clark – Postdoctoral Fellow (2018-2023)

    Current position: Assistant Professor, Oregon State University

     
  • Prashant Rao – Graduate Student (2017-2023)

    Current position: Calico Life Sciences

     
  • Dongxue Yang – Postdoctoral Fellow (2016-2022)

    Current position: Research, Institute of Urology, West China Hospital

     
  • Hongtao Zhu – Postdoctoral Fellow (2015-2022)

    Current position: Faculty, Institute of Physics, Chinese Academy of Sciences

     
  • Prerana Gogoi – Postdoctoral Fellow (2020-2022)

    Current position: Technical Director, Institute of Structural Biology, University of Pennsylvania

     
  • Farzad Jalali-Yazdi – Postdoctoral Fellow (2016-2021)

    Current position: Structural Biology & Biophysics Senior Research Scientist, Vertex Pharmaceuticals

     
  • Jie Yu – Postdoctoral Fellow (2016-2021)

    Current position: Principal Investigator, Interdisciplinary Research Center on Biology and Chemistry, Chinese Academy of Sciences

     
  • Jingpeng Ge – Postdoctoral Fellow (2016-2021)

    Current position: Assistant Professor, School of Life Science and Technology, ShanghaiTech University

     
  • Johannes Elferich – Postdoctoral Fellow (2015-2021)

    Current position: Research Specialist, Grigorieff lab, University of Massachusetts Medical School

     
  • Jonathan Coleman – Postdoctoral Fellow (2013-2020)

    Current position: Assistant Professor, University of Pittsburgh

     
  • Vikas Navratna – Postdoctoral Fellow (2015-2020)

    Current position: Research Investigator, Mosalaganti lab, University of Michigan, Life Sciences Institute

     
  • Nathan Yoder – Postdoctoral Fellow (2014-2019)

    Current position: Scientist, Amgen

     
  • Shanshuang Chen – Postdoctoral Fellow (2014-2019)

    Current position: Principal Investigator, Shanghai Institute of Precision Medicine

     
  • Shian Liu – Postdoctoral Fellow (2018-2019)

    Current position: Research Associate in Physiology and Biophysics, Weill Medical College of Cornell University

     
  • Swastik Phulera – Postdoctoral Fellow (2017-2019)

    Current position: Senior Scientist, Initium Therapuetics Inc

     
  • Sandipan Chowdhury – Postdoctoral Fellow (2014-2018)

    Current position: Assistant Professor of Molecular Physiology and Biophysics, University of Iowa Health Care, Carver College of Medicine

     
  • Xianqiang Song – Postdoctoral Fellow (2014-2018)

    Current position: Director of Structural Biology, Structure Therapeutics

     
  • Yan Zhao – Postdoctoral Fellow (2015-2018)

    Current position: Principal Investigator, National Laboratory of Biomacromolecules, IBP, Chinese Academy of Sciences

     
  • Juan Du – Postdoctoral Fellow (2012-2017)

    Current position: Associate Professor, Department of Structural Biology, Van Andel Institute

     
  • Wei Lu – Postdoctoral Fellow (2012-2017)

    Current position: Associate Professor, Department of Structural Biology, Van Andel Research Institute

     
  • Katharina Duerr – Postdoctoral Fellow (2010-2016)

    Current position: Principal Investigator, University of Oxford

     
  • Lei Chen – Postdoctoral Fellow (2010-2016)

    Current position: Principal Investigator, Peking University, Institute of Molecular Medicine

     
  • Steven Mansoor – Postdoctoral Fellow (2012-2016)

    Current position: Assistant Professor of Medicine, Division of Cardiovascular Medicine, School of Medicine, OHSU and Assistant Professor of Chemical Physiology and Biochemistry, School of Medicine, OHSU

     
  • Shujia Zhu – Postdoctoral Fellow (2014-2016)

    Current position: Principal Investigator, Institute of Neuroscience, Chinese Academy of Sciences

     
  • Aravind Penmatsa – Postdoctoral Fellow (2010-2015)

    Current position: Assistant Professor, Molecular Biophysics Unit, Indian Institute of Science

     
  • Chia-Hsueh Lee – Graduate Student (2009-2015)

    Current position: Assistant Member, St. Jude Children's Hospital, Memphis, TN

     
  • Kevin Wang – Postdoctoral Fellow (2010-2015)

    Current position: Structural Biologist, Relay Therapeutics

     
  • Derek Claxton – Postdoctoral Fellow (2011-2014)

    Current position: Research Assistant Professor, Machourab Lab, Dept. of Molecular Physiology and Biophysics, Vanderbilt University

     
  • Thorsten Althoff – Postdoctoral Fellow (2011-2014)

    Current position: Associate Project Scientist, UCLA

     
  • Hui Wang – Postdoctoral Fellow (2009-2013)

    Current position: Senior Principal Scientist and Group Leader, Pfizer

     
  • Isabelle Baconguis – Graduate Student (2007-2013)

    Current position: Assistant Scientist, Vollum Institute, Oregon Health and Science University

     
  • Michihiro Suga – Postdoctoral Fellow (2010-2012)

    Current position: Professor, Okayama University, Research Institute for Interdisciplinary Science

     
  • Motoyuki Hattori – Postdoctoral Fellow (2009-2012)

    Current position: Professor, Dept. of Physiology and Biophysics, School of Life Sciences, Fudan University

     
  • Ryan Hibbs – Postdoctoral Fellow (2007-2012)

    Current position: Professor and Vice Chair, UC San Diego

     
  • Chayne Piscitelli – Graduate Student (2005-2011)

    Current position: Senior Scientist, Zymeworks Inc.

     
  • Harini Krishnamurthy – Postdoctoral Fellow (2006-2011)

    Current position: Principal Scientist, Merck Research Labs

     
  • Juine-Ruey Chen – Postdoctoral Fellow (2011)

    Current position: Research & Development Department Manager, Adimmune Corporation

     
  • Ricarda Hilf – Postdoctoral Fellow (2010-2011)

    Current position: Head of Quality Management & Scientific Affairs, Verfora

     
  • Alexander Sobolevsky – Postdoctoral Fellow (2004-2010)

    Current position: Associate Professor, Columbia University

     
  • Satinder Singh – Postdoctoral Fellow (2002-2010)

    Current position: Associate Professor, Dept. Cellular & Molecular Physiology, Yale University

     
  • Toshimitsu Kawate – Postdoctoral Fellow (2005-2009)

    Current position: Associate Professor, Cornell University Dept. of Molecular Medicine, Cornell College of Veterinary Medicine

     
  • Neali Armstrong – Graduate Student/Postdoctoral Fellow (1998-2005)

    Current position: Academic Scientist, Stanford

     
  • Olga Boudker – Postdoctoral Fellow (2001-2005)

    Current position: Professor, Cornell and Principal Investigator, HHMI

     
  • Rongsheng Jin – Graduate Student (2000-2005)

    Current position: Professor, UC Irvine