Ongoing Trials

The Brenden-Colson Center as well as other departments at OHSU are involved in a number of clinical trials for pancreatic cancer early detection and treatment.  For more information, please visit and search in the Other Terms field by the NCT number of the trial.

Title OHSU Lead Investigator number
Monitoring Heart Rate Variability for the Early Detection of Pancreatic Cancer Aaron Grossberg, MD, PhD NCT04400903
Evaluation of a mixed meal test for Diagnosis and characterization of Type 3c diabeTes mellitus secondary to pancreatic cancer and chronic pancreatitis (DETECT) - Early Detection Brett Sheppard, MD NCT03460769
A Study of IMMrayTM PanCan-d Test for Early Detection of Pancreatic Cance in High-risk Groups Brett Sheppard, MD NCT03693378
Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy Brett Sheppard, MD NCT04965311
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC Charles Lopez, MD, PhD NCT03257033
Targeted PARP or MEK/ERK Inhibition in Patients With Pancreatic Cancer (WOO-M IIT) Charles Lopez, MD, PhD NCT04005690
NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer Charles Lopez, MD, PhD NCT04539808
Safety and Efficacy Study of AVB-S6-500 in Patients With Advanced Pancreatic Adenocarcinoma Charles Lopez, MD, PhD NCT04983407
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) Christopher W. Ryan, MD NCT02465060
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Christopher W. Ryan, MD NCT02834013
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment Emerson Chen, MD NCT04083235
CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Solid Tumors Jacqueline Vuky, MD NCT03425279
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors Matthew Taylor, MD Jacqueline Vuky, MD Shivaani Kummar, MD NCT03485209
Study of ADCT-301 in Patients With Selected Advanced Solid Tumors Shivaani Kummar, MD NCT03621982
A Study of SGN-CD228A in Advanced Solid Tumors Shivaani Kummar, MD NCT04042480
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors Shivaani Kummar, MD NCT04383210