Welcome to the Estes Laboratory! Our lab capitalizes on the full power of microscopy by performing cutting-edge in-vivo and in-situ tissue analyses. Our work is at the forefront of using next-generation ISH and IHC to generate comprehensive characterizations of host-pathogen interactions.
Estes Lab - learn more

Welcome to the Caposio Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. Our laboratory team has a long-standing interest in understanding complex virus-host interactions that define the mechanisms by which DNA viruses persist in the host.
Caposio Lab - learn more

Welcome to the DeFilippis Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus.  We are an interactive laboratory team working on understanding the roles of innate immunity in antiviral, and anti-cancer immune protection. This includes the establishment of direct antiviral states as mediated by interferons and cytokines, as well as ways in which this can be used to enhance viral vaccines and kill tumors.
DeFilippis Lab -learn more

Welcome to the Frueh Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. Our lab aims at understanding the molecular mechanism that enable some of the unique features of a new vaccine platform based on cytomegalovirus (CMV). These features are the ability to 1) maintain high frequencies of protective T cells to foreign antigens for life, 2) elicit such responses in CMV-immune hosts, 3) maintain immunogenicity even when highly attenuated, 4) program T cell responses that are distinct with respect to epitope targeting and MHC restriction. Frueh Lab - learn more

Welcome to the Hancock Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. We are a team of scientists working to understand the pathogenesis of human cytomegalovirus and how to utilize the unique properties of the virus as a vaccine vector.
Hancock Lab - learn more

Welcome to the Hansen Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus.  We are a diverse team of scientists focused on understanding the immunobiology of recombinant CMV vectors in human and non-human primate models to generate vaccine vectors with the capacity to protect against progressive HIV/SIV, and Mycobacterium tuberculosis (M.tb.) infection. Hansen Lab - learn more

Welcome to the Hirsch Laboratory, located at the Vaccine and Gene Therapy Institute at the Oregon Health & Science University. We are a group of scientists working on understanding the mechanisms of virus-host interactions and the molecular biology of flaviviruses, including Dengue, West Nile, Zika, and Powassan virus. Hirsch Lab - learn more

Content coming soon, Please check back at a later date. Moses Lab - learn more

Welcome to the Nelson Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus.  Our lab team is focused on understanding the molecular basis for Human Cytomegalovirus (HCMV) infection, including how the virus goes latent and reactivates from latency. We are also involved in collaborative projects across VGTI using cytomegalovirus as a vaccine vector. Nelson Lab - learn more

Welcome to the Okoye Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus.  Our team is interested in understanding the mechanisms by which human immunodeficiency virus (HIV) persists during antiretroviral therapy, and investigating novel therapies that may lead to a cure for HIV. Okoye Lab - learn more

Welcome to the Picker Laboratory located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. Our laboratory utilizes the nonhuman primate models to study T cell responses to persistent, immune evasive agents such CMV, SIV/HIV and M. tuberculosis.  We have developed a revolutionary vaccine platform, based on CMV, to combat immune evasive pathogens. In addition, we are investigating ways to cure individuals of HIV infection using the SIV Rhesus macaque model. Picker Lab - learn more

Welcome to the Skalsky Laboratory located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus.  Our laboratory research focuses on Epstein-Barr virus, a ubiquitous herpesvirus that causes infectious mononucleosis that is also linked to a number of cancers, and autoimmune diseases. Skalsky Lab - learn more

Welcome to the Smedley Laboratory located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. We are a dedicated group of veterinary scientists developing, optimizing and conducting macaque models of infectious disease, immunity, and inflammation.  We specialize in comprehensive sampling, minimally invasive surgery, imaging, and collaborative science on macaque models of inflammation, immunity, imaging, surgery, and infectious diseases. Smedley Lab - learn more

Welcome to the Streblow Laboratory located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus Our laboratory team focuses on viral pathogenesis and anti-virals targeting new and re-emerging DNA and RNA viruses. Additionally, we focus on models of CMV mediated transplant rejection.  Streblow Lab - learn more

Welcome to the Wilder Laboratory located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. We are a team of scientists working to advance our understanding of the immune response to malaria infection, developing vaccines and therapeutics to help drive malaria towards eradication. Wilder Lab - learn more

Welcome to the Wong Laboratory, located at the Vaccine and Gene Therapy Institute at Oregon Health & Science University, West Campus. Our laboratory employs state-of-the-art molecular, genetic and virological techniques to elucidate how simian gamma-herpesviruses infect and replicate in cell culture and eventually how they cause illnesses in vivo. We were the first to demonstrate that experimental inoculation of immunocompromised monkeys with simian herpesviruses results in disease manifestations that closely resemble those observed in people living with HIV. Utilizing these approaches, they are identifying the viral determinants that contribute to disease and are developing novel recombinant simian herpesviruses to help prevent viral disease. Wong Lab - learn more