Publications

2019

  • Mitrugno, A; Tunga, SY; Sylman, J; Zilberman-Rudenko, J; Shirai, T; Hebert, J; Kayton, R; Zhang, Y; Nan, XL; Shatzel, J; Esener, S; Duvernay, M; Hamm, H; Gruber, A; Williams, C; Takata, Y; Armstrong,R; Morgan, T; and McCarty, OJT. The role of coagulation and platelets in colon cancer-associated thrombosis. Am. J. Phys. Cell. Phys. 316(2): C264-C273, 2019. https://doi.org/10.1152/ajpcell.00367.2018
  • Lee, Y; Phelps, C; Huang, T; Mostofian, B; Wu, L; Zhang, Y; Tao, K; Chang, YH; Stork, PJS; Gray, JW; Zuckerman, DM*, Nan, XL*. High-throughput single-particle tracking reveals nested membrane domains that dictates KRasG12D diffusion and trafficking. eLife, 8:e46393, http://doi.org/10.7554/eLife.46393. Originally posted on BioRxiv (https://doi.org/10.1101/552075).
  • Mulqueen, RM; DeRosa, BA;  Thornton, CA; Sayar, Z; Torkenczy, KA; Fields, AJ; Wright, KM; Nan, XL; Ramji, R; Steemers, FJ; O'Roak, BJ; Adey, AC. Improved single-cell ATAC-seq reveals chromatin dynamics of in vitro corticogenesis. BioRxiv 637256; doi: https://www.biorxiv.org/content/10.1101/637256v1

2018

  • Su, YL; Pelz, C; Huang, T; Torkenczy, K; Wang, XY; Cherry, A; Daniel CJ; Liang, J; Nan, XL; Dai, MS; Adey, A; Impey, S; Sears, RC. Pos-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular response to environmental signals. Genes & Dev. 2018 Nov 1;32(21-22):1398-1419. doi: 10.1101/gad.314377.118

  • Bittel, AM; Salvidar, IS; Dolman, NJ; Nan XL; Gibbs, SL. Superresolution microscopy with novel BODIPY-based fluorophores. PLoS ONE 13(10): e0206104. https://doi.org/10.1371/journal.pone.0206104

  • Yu, GT; Rao, L; Wu, H; Yang, LL; Bu, LL; Deng, WW; Wu, L; Nan, XL; Zhang, WF; Zhao, XZ, Liu, W; Sun, ZJ. Myeloid-derived suppressor cell membrane-coated magnetic nanoparticles for cancer theranostics by inducing macrophage polarization and synergizing immunogenic cell death. Adv. Func. Mat. 1801389 (2018). Download PDF.

  • Huang, T; Phelps, C; Wang, J; Lin, LJ; Bittel, A; Scott, Z; Jacques, S; Gibbs, SL; Gray, JW; Nan, XL*. Simultaneous multicolor single-molecule tracking with single-laser excitation via spectral imaging. Biophys. J., 114, 301 (2018). view online

2017

  • Ritchie, C; Mack, A; Harper, L; Alfadhli, A; Stork, PJS; Nan, XL; Barklis, E*. Analysis of K-Ras Interactions by biotin ligase tagging. Cancer Genomics Proteomics. 14, 225 (2017). view online
  • Zhang, Y; Huang, T; Jorgens, DM; Nickerson, A; Lin, LJ; Pelz, J; Gray, JW; Lopez, CS*; Nan, XL*. Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy. PLoS One, 12(5), e0176839 (2017). view online
  • Creech, MK; Wang, JNan, XL*; Gibbs, SL*. Superresolution imaging of clinical formalin fixed paraffin embedded breast cancer with single molecule localization microscopy. Sci. Rep., 7, 40766 (2017). view online

2016

  • Bittel, AM; Nickerson, A; Saldivar, IS; Dolman, NJ; Nan, XL; Gibbs, SL. Methodology for quantative characterization of fluorophore photoswitching to predict superresolution microscopy image quality. Sci. Rep., 6, 29687 (2016). View online
  • Sylman, JL; Daalkhaijav, U; Zhang, Y; Gray, EM; Farhang, PA; Chu, TT; Zilberman-Rudenko, J; Puy, C; Tucker, EI; Smith, SA; Morrissey, JH; Walker, TW; Nan, XL; Gruber, A; McCarty, OJT. Differential roles of Coagulation Factor XI and XII in regulating the physical biology of fibrin. Ann. Biomed. Eng., 45(5), 1328(2016). View online
  • Chen, M; Peters, A; Huang, T; Nan, XL*. Ras dimer formation as a new signaling mechanism and potential cancer therapeutic target. mini-Review in Medicinal Chemistry, 16, 391(2016). View online
  • Peters, A; Nickerson, A; Lin, LJ; Nan, XL*. Quantitative superresolution microscopy for cancer biology and medicine. In Super-resolution Imaging in Medicine and Biology. Edited by Alberto Diaspro and Marc AMJ van Zandvoort. Taylor & Francis Books, Inc. (2016).

2015

  • Nan, XL*; Meyer-Tamguney, T ; Collisson, EA ; Lin, LJ ; Pitt, C ; Galeas, J ; Lewis, S ; Gray, JW*; McCormick, F*; Chu, S*. Ras-GTP dimers activate the mitogen-activated protein kinase (MAPK) pathwayPNAS, 112(26), 7996 (2015). 
    Also view the commentary on our article, 'Seeing is believing - Ras dimers visualized in live cells' by Drs. Mark Philips and Channing Der.
  • Nickerson, A; Huang, T; Lin, LJ; Nan, XL*. Photoactivated localization microscopy with bimolecular fluorescence complementation (BiFC-PALM). J. Vis. Exp., 106, e53154 (2015). doi: 10.3791/53154
  • Baker-Groberg, S; Phillips, KG; Healy, LD; Itakura, A; Porter, JE; Newton, PK; Nan, XL; McCarty, OJT. Critical behavior of subcellular density organization during neutrophil activation and migration. Cellular and Molecular Bioengineering, 8(4), 543 (2015).

2014

  • Nickerson, A; Huang, T; Lin, LJ; Nan, XL*. Photoactivated localization microscopy with bimolecular fluorescence complementation (BiFC-PALM) for nanoscale imaging of protein-protein interactions in cells. PLoS ONE. 9(6), e100589 (2014). View online

2013

  • Nan, XL*; Collisson, EA; Kuo, SYL ; Huang, J; Meyer, TM; Liphardt, J; McCormick, F; Gray, JW; Chu, S. Quantitative single-molecule superresolution imaging allows visualization of Raf dimerization and signaling. PNAS, 110(46), 18519 (2013). Highlighted in Sci. Transl Med: 5, 211ec187 (2013). View online
  • Itakura, A; Aslan, JE; Kusanto, BT; Phillips, KG; Nan, XL; Insall, RH; Chernoff, JC; McCarty, OJT. p21-activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils. PLoS ONE, 8(9), e73063:1 (2013). View online
  • Ying, H; Nan, XL; Sengupta, P; Lippincott-Schwartz, J ; Cang, H. Accelerating 3B single molecule super-resolution microscopy with cloud computing. Nature Methods, 10, 96 (2013). View online

Prior to OHSU