ALPS/Immune Deficiency

Orderable EAP code:

LAB01145

Billable EAP Codes:

80002136 x 1 (First)
80002137 x 24 (Additional)
88189 x 1 (Profee)

CPT Codes:

88184 x 1 (First)
88185 x 24 (Additional)
88189 x 1 (Profee)

Lab Section:

Flow Cytometry

Turnaround Time:

Routine: 5 days

Test Schedule:

Monday through Friday, 8:00 am to 4:30 pm; Saturday and Sunday 9:00 am to 4:00 pm.

Interpretation:

Test results are interpreted by a Hematopathologist.

Specimen Requirements:

6 mL blood in a LAVENDER top (EDTA) tube. Room temperature samples are good for up to 24 hours.
Results from a concurrent CBC with Differential must be received, or it will be added and charged to viable specimens.

Pediatric Specimen Requirements:

1 mL blood in a 3 mL LAVENDER top (EDTA) tube. Room temperature samples are good for up to 24 hours.
Results from a concurrent CBC with Differential must be received, or it will be added and charged to viable specimens.

Reference Range:

Refer to report.

Comments:

The Immunodeficiency and Autoimmune Lymphoproliferative Syndrome (ALPS) Flow Cytometry panel allows quantitative lymphocyte subset analysis in the work-up of primary and secondary immunodeficiencies and ALPS. Quantitative assessment of T-cells, B-cells, and NK-cells are provided. For ALPS evaluation, the percentage of double negative, tCR alpha/beta positive T-cells are determined as well as CD45R(B220) expression, which is also commonly elevated in ALPS. The Immunodeficiency/ALPS Flow Cytometry test is a quantitative test and is not intended to detect functional lymphocyte defects.    

Synonyms:

Autoimmune Lymphoproliferative Disorders (ALPS)
Immune Deficiency