Lab publications

  1. Diggins NL, Crawford LB, Hancock MH, Mitchell J, Nelson JA. Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA To Inhibit CD34+Hematopoietic Progenitor Cell Proliferation To Maintain the Latent Viral Genome. mBio. 2021 Apr 6;12(2):e00621-21. doi: 10.1128/mBio.00621-21. PMID: 33824207; PMCID: PMC8092260.
     
  2. Hansen SG, Hancock MH, Malouli D, Marshall EE, Hughes CM, Randall KT, Morrow D, Ford JC, Gilbride RM, Selseth AN, Trethewy RE, Bishop LM, Oswald K, Shoemaker R, Berkemeier B, Bosche WJ, Hull M, Silipino L, Nekorchuk M, Busman-Sahay K, Estes JD, Axthelm MK, Smedley J, Shao D, Edlefsen PT, Lifson JD, Früh K, Nelson JA, Picker LJ. Myeloid cell tropism enables MHC-E-restricted CD8+ T cell priming and vaccine efficacy by the RhCMV/SIV vaccine. Sci Immunol. 2022 Jun 24;7(72):eabn9301. doi: 10.1126/sciimmunol.abn9301. Epub 2022 Jun 17. PMID: 35714200; PMCID: PMC9387538.
     
  3. Crawford LB, Hancock MH, Struthers HM, Streblow DN, Yurochko AD, Caposio P, Goodrum FD, Nelson JA. CD34+ 
    Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence. J Virol. 2021 Jan 13;95(3):e02105-20. doi: 10.1128/JVI.02105-20. PMID: 33177198; PMCID: PMC7925096.
     
  4. Hancock MH, Mitchell J, Goodrum FD, Nelson JA. Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways. mSphere. 2020 Aug 5;5(4):e00582-20. doi: 10.1128/mSphere.00582-20. PMID: 32759334; PMCID: PMC7407068.
     
  5. Hancock MH, Crawford LB, Pham AH, Mitchell J, Struthers HM, Yurochko AD, Caposio P, Nelson JA. Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34+ Hematopoietic Progenitor Cells. Cell Host Microbe. 2020 Jan 8;27(1):104-114.e4. doi: 10.1016/j.chom.2019.11.013. Epub 2019 Dec 19. PMID: 31866424; PMCID: PMC6952548.