Flow Cytometry

OHSU offers a full flow cytometry service to aid in the evaluation of a variety of clinical problems such as:

  • Lymphoma/leukemia
  • Immunodeficiency and Autoimmune disorders
  • Lymphocyte activation for bone marrow transplant patients
  • Paroxysmal nocturnal hemoglobinuria (PNH), hereditary platelet disorders (Bernard-Soulier Syndrome and Glansmann's thrombasthenia)
  • Fetal maternal blood screening test

Flow Lab test menus:

Hematologic malignancies

  • Myeloid disorders
              Acute myeloid leukemias
              Chronic myeloproliferative neoplasms
              Chronic myeloproliferative/myelodysplastic neoplasms
  • Lymphoid disorders
              Acute lymphoblastic leukemia/lymphomas
              B-cells, T-cell, and NK-cell lymphomas, all subtypes
              Large granulocytic leukemia with Kir antibodies
              Plasma cell myelomas
              Sezary syndrome

MRD (minimal residual diseases) detection (sensitivity of 0.01%)

Acute lymphoblastic leukemia
Acute myeloid leukemia
Chronic lymphocytic leukemia

Immunodeficiency and autoimmune disorders

CVID (common variable immunodeficiency)
SCID (severe combined immunodeficiency)
ALPS (autoimmune lymphoproliferative disorders)
CD4 cell count
T-cell subset count: CD3/CD4/CD8
Lymphoid subset count: T, B, and NK cells

Stem cells and bone marrow transplant services:

CD34 count
CD34 count with T-cell quant
Immune reconstitution
Sorting for Chimerism

PNH: High sensitivity assay (0.01%)

Fetal hemoglobin testing

Platelet surface markers for hereditary platelet disorders

Flow sorting