It's that time of the year again! Sofiya joined us for a rotation in January, Shun-Je will be in the lab in March and Xammy, who's in the MD-PhD program will rotate mid-March to mid-April. Sofiya was off to a great start, working with Madeline on tuft cell experiments. We went to have margaritas for end of rotation celebrations, which seems to become a tradition.
Alexis gets a fellowship! Gingerbread time
We are every proud to report that Alexis got the Cancer Research Institute postdoctoral fellowship for her work on epithelial cell extrusion mechanisms awarded. To celebrate, we had margaritas, and Alexis surprised us all with matching headbands she had crocheted.
For our holiday party, we made gingerbread houses, which where very stable due to lots of frosting used but still did not survive for very long....
For the new year, we are excited about more great science and hosting rotation students in the lab.
Retreat! Madeline wins an award! Halloween!
After 2 years of hiatus MMI finally had an in person retreat again! It was great fun and full of fantastic science. Alexis gave an excellent talk, Marin presented a beautiful poster and Madeline won the 2022 Sears Microbiology Fellowship Award! Congratulations!!
As is tradition already , we also carved pumpkins with the Pruneda lab again. New this year, we did a lab halloween costume! Our ambition is to convince the whole department next year...
The Rauch Lab visits ICMI
Bella gave a lecture on mucosal immune sensing for the "principals of mucosal immunology" course at the International Congress of Mucosal Immunology and Alexis presented a poster; more exactly, Madelines poster, as unfortunately Madeline got sick and couldn't come :-(
Marin got a training award and we published a paper
Just having joined the lab, Marin already got awarded an appointment on the NIH Ruth L Kirschstein T32 Program in Biomedical Sciences (PBMS) training grant. Congratulations!!
We published a collaborative paper with Sunny Shins lab at UPenn about the inflammasomes important for Salmonella recognition in human intestinal epithelial cells. Great work from Renate Bauer during her productive visit to the lab! Prepare to be surprised!
A group conference visit, congratulations Alexis and good bye William
With AAI 2022 happening in Portland, the whole lab got to go and learn about all the amazing immunology research. And we found the photo booth at the gala.....
Alexis graduate work got published, and she is looking forward to fully focus on her postdoctoral research!
William had his last day in the lab. He won't go far though as he's joining the OHSUs PBMS program- we are excited to see which lab he will join for his graduate work!
Welcome to the lab Marin!
Marin rotated in the lab in March and we are thrilled that she decided to join us for her graduate studies! Marin comes to us from the University of Denver and will work on pathogenic interference with epithelial cell extrusion.
More rotations, William goes to graduate school!
Welcome to Leah for her rotation, in which she will continue Allisons work on detection of Salmonella inside epithelial cells! Also, huge congratulations to William who has been accepted to graduate school!!!!
Alexis is here, Allison rotates, William published a paper and we got funding!
Welcome to the lab to Alexis, the teams first postdoc, and Allison, our first rotation student for the year!
Huge congratulations to William who got his first co-author from the lab on a collaborative paper with the Shin lab!
The lab got its first NIH R01 funding to study the role of the inflammasome in tuft cells! Kudos to Madeline and Renate for generating the crucial preliminary data for this grant!
Fellowship for Alexis, pumpkins, and a new review
Congratulations to our incoming postdoctoral fellow Alexis Gibson, who already scored a fellowship before she even started! Thank you to OFDIR for supporting her!
We hung out with the Pruneda lab to carve some pumpkins again this year. After last year's freezing outdoor carving event we all felt grateful for our booster shots that allowed us meeting indoors this year.
Our review about pyroptosis in epithelial barriers is out! We wrote it together with our friend Patrick from the Mitchell Lab. Come to learn all about this fascinating topic, stay for Madeline's great illustrations and our discussion on where the field is going!
Lab summer outing
We couldn't have a retreat this year but we could have some distanced outdoor fun with the Pruneda lab. Everyone crushed it at mini golf and corn hole!
Madeline's first paper from the lab is out! She contributed important data showing that tuft cells can make the prostaglandin D2 to a study from the Tait Wojno lab.
The Vance lab published a study showing that inflammasome triggered epithelial cell extrusion is protecting mice from Shigellosis, and we helped!
The Lab's first last author paper is out!
This study was in large parts still performed at UC Berkeley and we are very thankful to the Vance lab, and especially the fantastic first author Jeannette Tenthorey. We are addressing the role of NLRC4 phosphorylation in the function of the NAIP/NLRC4 inflammasome as well as the role of NLRC4 in melanoma. Very surprisingly, we do not find any of the previously described phenotypes in our separately generated mouse lines!
Renate's review on NAIP/NLRC4 is out
During her super productive visit in our lab, Renate ALSO wrote a great review on the NAIP/NLRC4 inflammasome in infection and pathology. Check it out!
The lab had its first ever pumpkin carving evening which we plan to make a tradition. Amazing creativity by both the Rauch and Pruneda lab members!