Publications
Selected publications
Gaglia, G.*, Burger, M.L.*, Ritch, C.C., Rammos, D., Yang, D., Crossland, G.E., Tavana, S.Z., Warchol, S., Jaeger, A.M., Coy, S., Johnson, A., Krueger, R., Lin, J.R., Pfister, H., Sorger, P., Jacks, T., Santagata, S. Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma. Cancer Cell doi: 10.1016/j.ccell.2023.03.015 (2023).
Patel, R., Romero, R., Liang, A., Watson, E., Burger, M.L., Westcott, P.M.K., Mercer, K., Bronson, R., Wooten, E., Bhutkar, A., Jacks, T., Elledge, S. A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells. Nat Communications 13(1):256. doi: 10.1038/s41467-021-27731-5 (2022).
Hamza, B., Miller, A.B., Meier, L., Stockslager, M., Ng, S.R., King, E.M., DeGouveia, K.L., Mulugeta, N., Calistri, N.L., Strouf, H., Lin, L., Chin, C.R., Bray, C., Rodriguez, F., Freed-Pastor, W.A., Jaramillo, G.C., Burger, M.L., Weinberg, R.A., Shalek, A.K., Jacks, T., Manalis, S. Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice. Nat Communications 12(1):5680. doi:10.1038/s41467-021-25917-5 (2021).
Burger, M.L., Cruz, A.M., Crossland, G.E., Gaglia, G., Ritch, C.C., Blatt, S.E., Bhutkar, A., Canner, D., Kienka, T., Tavana, S., Garmilla, A., Schenkel, J.M., Hillman, M., de los Rios Kobara, I., Li, A., Hwang, W.L., Westcott, P.M.K., Regev, A., Santagata, S., Jacks, T. Antigen dominance hierarchies shape TCF1+ CD8 T cell phenotypes in tumors. Cell 184(19):4996-5014. doi:10.1016/j.cell.2021.08.020 (2021).
Schenkel, J.M., Herbst, R.H., Canner, D.A., Li, A., Hillman, M., Shanahan, S., Gibbons, G., Smith, O.C., Kim, J.Y., Westcott, P., Hwang, W., Freed-Pastor, W., Eng, G., Cucco, M.S., Rogers, P., Park, J.K., Burger, M.L., Rozenblatt-Rosen, O., Cong, L., Pauken, K.E., Regev, A., Jacks, T. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor draining lymph nodes. Immunity 54(10):2338-2353.e6. doi:10.1016/j.immuni.2021.08.026 (2021).
Burger, M.L., Leung, K.K., Bennett, M.J., Winoto, A. T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity. eLIFE3:e03468. doi: 10.7554/eLife.03468 (2014).
Burger, M.L.*, Xue, L.*, Sun, Y., Kang, C., Winoto, A. Premalignant PTEN-deficient thymocytes activate miR-146a and miR-146b as a cellular defense against malignant transformation. Blood 123(26):4089-4100. doi: 10.1182/blood-2013-11-539411 (2014).
Thompson, J., Burger, M.L., Whang, H., Winoto, A. Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis. Eur J Immunol 40(7):2041-2049. doi: 10.1002/eji.200940231 (2010).