Orderable EAP code:

LAB00260

Billable EAP Codes:

80001098 x 1

CPT Codes:

85230 x 1

Lab Section:

Hemostasis and Thrombosis

Turnaround Time:

1 to 3 days

Test Schedule:

Monday, Wednesday, and Friday 

Units:

%

Critical Values:

Less than 5%

Specimen Requirements:

Two full 2.7 mL LIGHT BLUE top tubes, 3.2% sodium citrate.  Specimens must be processed and frozen within 2 hours of specimen collection.

Send 2- 1mL aliquots of platelet poor plasma, samples must remain frozen during storage and shipment. 

Stability is 14 days at -20 °C or at -70 °C for up to 12 months. 

Detailed specimen collection and processing instructions are located under Lab Sections and then the Hemostasis and Thrombosis (Opens in a new window) section.

Pediatric Specimen Requirements:

1 full pediatric 1.3 mL LIGHT BLUE top tube, 3.2% sodium citrate. Specimens must be processed and frozen within 2 hours of specimen collection.

Send 1 600 uL aliquot of platelet poor plasma, samples must remain frozen during storage and shipment, 

Stability is 14 days at -20 °C or at -70 °C for up to 12 months. 

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

50% to 129%

For children less than 6 months, see link to published reference ranges (Opens in a new window).

Comments:

Avoid warfarin (Coumadin) therapy for 2 weeks and heparin therapy for 2 days prior to the test.

Assay to document factor VII deficiency. Deficiency of factor VII should be considered in patients with a prolonged prothrombin time but a normal APTT. While isolated deficiency is rare, two forms exist. Both are autosomal recessive and affect both sexes. In one form the VII molecules are decreased while In the second group an abnormally formed molecule is produced. Bleeding symptoms may be severe in homozygotes and include epistaxis, ecchymoses, GI bleeding, hemarthroses, menorrhagia, and umbilical cord hemorrhage. Fatal cerebral hemorrhage may occur. Heterozygotes are usually asymptomatic. Homozygotes have prolonged prothrombin time (corrected by adding normal plasma) but normal APTT, cephalin activated clotting time, and thrombin time.

Methodology: PT based clotting method.

High doses of standard heparin (greater than 1.0 U/mL) may interfere with a PT mixing study. Anti-Xa agents such as Rivaroxaban may also interfere with PT mixing studies. Clinical correlation is advised.

Synonyms:

F7A

Factor 7

FVII A