Von Willebrand Factor Antigen Assay

Orderable EAP code:

LAB00238

Billable EAP Codes:

80001090 x 1

CPT Codes:

85246 x 1

Lab Section:

Hemostasis and Thrombosis

Includes:

This assay is included in Von Willebrand Panel.

Turnaround Time:

1 to 3 days

Test Schedule:

Monday, Wednesday, Friday 

Units:

%

Critical Values:

Less than 19%

Specimen Requirements:

Two full 2.7 mL LIGHT BLUE top tube, 3.2% sodium citrate. Specimens must be processed and frozen within 2 hours of specimen collection.

Send 2- 1 mL aliquots of platelet poor plasma, samples must remain frozen during storage and shipment. 

Stability is 14 days at -20°C or at -70°C for up to 12 months. 

Detailed specimen collection and processing instructions are located under Lab Sections and then the Hemostasis and Thrombosis (Opens in a new window) section.

Pediatric Specimen Requirements:

One full pediatric 1.3 mL LIGHT BLUE top tube, 3.2% sodium citrate. Specimens must be processed and frozen within 2 hours of specimen collection.

Send 1 600uL aliquot of platelet poor plasma, samples must remain frozen during storage and shipment. 

Stability is 14 days at -20°C or at -70°C for up to 12 months. 

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

42% to 176%

Comments:

This test is used in the diagnosis, classification, and treatment of von Willebrand disease.

Von Willebrand disease is characterized by easy bruising or prolonged bleeding from mucosal surfaces due to reduced vWF concentration (Type I), qualitative dysfunction (Type II) or complete loss of production (Type III). Both quantitative and qualitative (functional) assays are required for the diagnosis and appropriate therapeutic intervention. Because many patients with vWD have mild disease, repeated testing may be necessary to diagnose this disorder. Normal values do not exclude vWD. Female patients with vWD on oral contraceptives or who are pregnant may have normal values. Von Willebrand factor is also an acute-phase reactant and is elevated with stress or exercise.

Methodology: Immunoturbidometric assay.

Synonyms:

VWF AG