Protein S Antigen, Free

Orderable EAP code:

LAB00321

Billable EAP Codes:

80001102 x 1

CPT Codes:

85306 x 1

Lab Section:

Hemostasis and Thrombosis

Turnaround Time:

3 Days 

Test Schedule:

Monday, Wednesday, and Friday 

Units:

%

Interpretation:

Patients on warfarin may have decreased free protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of free protein S levels. Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes.
 

Specimen Requirements:

Two full 2.7 mL LIGHT BLUE top tubes, 3.2% sodium citrate. 
Specimens must be processed and frozen within 2 hours of specimen collection.

Send 2- 1mL aliquots of platelet poor plasma, samples must remain frozen during storage and shipment. 

Stability is 14 days at -20 C or at –70°C for up to 12 months.

Detailed specimen collection and processing instructions are located under Lab Sections and then the Hemostasis and Thrombosis (Opens in a new window)section.

Pediatric Specimen Requirements:

One full pediatric 1.3 mL LIGHT BLUE top tube, 3.2% sodium citrate. 
Specimens must be processed and frozen within 2 hours of specimen collection. 

Send 1 600 uL aliquot of platelet poor plasma, samples must remain frozen during storage and shipment. 

Stability is 14 days at -20 C or at –70°C for up to 12 months.

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.
 

Reference Range:

Male = 41.1 – 146.0%

Female = 54.7% – 123.7%
 

Comments:

Recommended test to detect protein S deficiency. 
Free Protein S assay is not affected by Factor V Leiden mutation (APC-R).
 

Synonyms:

Free Protein S
Protein S