Orderable EAP code:

LAB00231

Billable EAP Codes:

80001087 x 6 85576.3 x 6 (Profee)

CPT Codes:

85576 x 6 85576 x 6 (Profee)

Lab Section:

Hemostasis and Thrombosis

Turnaround Time:

1 day

Test Schedule:

Specimen must be collected at OHSU PPV or DCH by appointment only. Schedule with Lab Client Services 503-494-7383.  Schedule appointments Tuesdays, 9:00 to 12:00, at least 1 hour apart and no more than 3 per day.

Specimen Requirements:

Patients should refrain from non-steroidal anti-inflammatory drugs, aspirin and aspirin containing products, (unless the patient is being checked for aspirin resistance) or dietary supplements known to affect platelet function 10-14 days prior to testing. 

Four FULL 2.7 mL whole blood LIGHT BLUE (3.2% sodium citrate) tubes and one 3 mL whole blood LAVENDER (EDTA).  Do NOT send in pneumatic tube system. Do NOT spin.

Stability is 3 hours at Room Temperature.
Sample must be received in SIC Lab within 1 hour of the draw.

Pediatric Specimen Requirements:

Patients should refrain from non-steroidal anti-inflammatory drugs, aspirin and aspirin containing products, (unless the patient is being checked for aspirin resistance) or dietary supplements known to affect platelet function 10-14 days prior to testing.

Three FULL 2.7 mL whole blood LIGHT BLUE (3.2% sodium citrate) tubes and one 3 mL whole blood LAVENDER (EDTA).  Do NOT send in pneumatic tube system. Do NOT spin.

Stability is 3 hours at Room Temperature.
Sample must be received in SIC Lab within 1 hour of the draw.

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

Reagent	Concentration	Reference Range	Units
Thrombin ATP Release	1 Unit/mL	greater than 0.5	nmole
Ristocetin Aggregation	0.25 mg/mL	less than 5	Ohms
Ristocetin Aggregation	1.0 mg/mL	greater than 5	Ohms
Collagen Aggregation	1 ug/mL	12 - 33	Ohms
Collagen ATP Release	1 ug/mL	0.43 - 2.2	nmole
Collagen Aggregation	5 ug/mL	11 - 42	Ohms
Collagen ATP Release	5 ug/mL	0.54 - 2.9	nmole
Arachidonic Acid Aggregation	0.5 mM	7 - 29	Ohms
Arachidonic Acid ATP Release	0.5 mM	0.45 - 2.7	nmole
ADP Aggregation	10 uM	6 - 33	Ohms
ADP ATP Release	10 ums	0.21 - 1.9	nmole

Comments:

This test is to screen for specific hereditary and acquired platelet functional abnormalities such as rare congenital disorders (Glanzmann's thrombasthenia and Bernard-Soulier syndrome).

Synonyms:

Aggregation
Plt Agg