Ninian Blackburn

Ninian Blackburn

Institute of Environmental Health and Division; Environmental and Biomolecular Systems
Office: Hatfield Research Center, 3rd floor, Room 353
Phone: 503-346-3428


Ph.D., Inorganic Chemistry; University of Dundee, Scotland, U.K., 1975


Research Interests

Research areas: Structure and function of oxidase and oxygenase metalloenzymes;coordination chemistry and biochemistry of copper with particular focus on the role of copper in neuroendocrine function, pathogen virulence, and cancer. Biochemistry of metal homeostasis in human and bacterial cells with emphasis on the mechanism of import, trafficking and export;spectroscopy of metal sites in proteins using EPR, EXAFS, absorption edge, X-ray emission and FTIR spectroscopies..


Selected Publications

Metallomics : integrated biometal science. 2016;
PubMed [journal]PMID: 27242196

Biochemistry. 2016;55(13):2008-21. NIHMSID: NIHMS784583
PubMed [journal]PMID: 26982589 PMCID: PMC4879618

Inorganic chemistry. 2016;55(7):3431-9. NIHMSID: NIHMS784573
PubMed [journal]PMID: 26965786 PMCID: PMC4878823

Contrast media &molecular imaging. 2016;11(2):154-9. NIHMSID: NIHMS784629
PubMed [journal]PMID: 26708733 PMCID: PMC4864039

Design of a single protein that spans the entire 2-V range of physiological redox potentials.
Hosseinzadeh P, Marshall NM, Chacón KN, Yu Y, Nilges MJ, New SY, Tashkov SA, Blackburn NJ, Lu Y.
Proceedings of the National Academy of Sciences of the United States of America. 2016;113(2):262-7.
PubMed [journal]PMID: 26631748 PMCID: PMC4720346

Multicopper manganese oxidase accessory proteins bind Cu and heme.
Butterfield CN, Tao L, Chacón KN, Spiro TG, Blackburn NJ, Casey WH, Britt RD, Tebo BM.
Biochimica et biophysica acta. 2015;1854(12):1853-9.
PubMed [journal]PMID: 26327317

Binuclear Cu(A) Formation in Biosynthetic Models of Cu(A) in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate.Chakraborty S, Polen MJ, Chacón KN, Wilson TD, Yu Y, Reed J, Nilges MJ, Blackburn NJ, Lu Y.
Biochemistry. 2015;54(39):6071-81. NIHMSID: NIHMS785067
PubMed [journal]PMID: 26352296 PMCID: PMC4877033

SSRL Science Highlight. 2014 October 31;
My Bibliography [journal]

Proceedings of the National Academy of Sciences of the United States of America. 2014;111(43):15373-8.
PubMed [journal]PMID: 25313055 PMCID: PMC4217431

Journal of the American Chemical Society. 2014;136(36):12532-5.
PubMed [journal]PMID: 25171435 PMCID: PMC4160276

Biochemistry. 2014;53(6):1069-80. NIHMSID: NIHMS561579
PubMed [journal]PMID: 24471980 PMCID: PMC3985755
Inorganic chemistry frontiers. 2014;1(2):153-158. NIHMSID: NIHMS555575
PubMed [journal]PMID: 24707355 PMCID: PMC3972132

Biochemistry. 2013;52(15):2586-96. NIHMSID: NIHMS465223
PubMed [journal]PMID: 23530865 PMCID: PMC3746079

Biochemistry. 2013;52(7):1179-91. NIHMSID: NIHMS556819
PubMed [journal]PMID: 23320946 PMCID: PMC3936603

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