Walker BS, Sutton TL, Zarour L, Hunter JG, Wood SG, Tsikitis VL, Herzig DO, Lopez CD, Chen EY, Mayo SC, and Wong MH. Circulating hybrid cells: A novel liquid biomarker of treatment response in gastrointestinal cancers. (2021) Annals of Surgical Oncology. [PMID: 34365557]. Visual abstract:

Dietz MS, Sutton TL, Walker BS, Gast GE, Zarour L, Sengupta SK, Swain JR, Eng J, Parappilly M, Limbach K, Sattler A, Burlingame E, Chin Y, Gower A, Mira JLM, Sapre A, Chiu YJ, Clayburgh DR, Pommier SE, Cetnar JP, Fischer JM, Jaboin JJ, Pommier RF, Sheppard BC, Tsikitis VL, Skalet AH, Mayo SC, Lopez CD, Gray JW, Mills GB, Mitri Z, Chang YH, Chin K, and Wong MH.Relevance of macrophage-cancer cell hybrids as a non-invasive biomarker for myriad solid tumors. (2021) Scientific Reports.11:13630. [PMCID:PMC8249418]. Epub: bioRxiv 2021.03.11.434896; doi:
-Received manuscript of the month honors at OHSU

Gast CE, Silk AS, Zarour L, Riegler L,  Burkhart J, Gustafson K, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Perera V, Schmidt M, Swain JR, Davies PS, Shashtri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer J, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard B, and Wong MH. Cell fusion potentiates intratumoral heterogeneity and reveals a circulating hybrid cell population. (2018) Science Advances. 9:7828. [PMCID:PMC6135550].
-Featured in the Knight Cancer Institute blog and Science special edition on Cancer.

Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Hernandez RE, Gast CE, Zarour LR, Antoku SM, Wong MH, Condeelis J, Moens CB. Macrophage-dependent cytoplasmic transfer drives melanoma invasion in vivo. (2017) Developmental Cell. 43:579. [PMCID:PMC5728704].

Kelley, KA, Wieghard N, Chin Y, Potter A, Mori M, Wong MH, Chin K, and Tsikitis VL. miR-486-5p downregulation marks an early even in colorectal carcinogenesis. (2018) Dis Colon Rectum 61:1290-1296. [PMCID:PMC6172144].

Smith NR, Swain JR, Davies PS, Gallagher AC, Streeter P, Williamson I, Magness S, and Wong MH. Novel monoclonal antibodies to intestinal stem cells reveal dynamic plasticity within the intestinal crypt. (2018) Cell Mol Gastroenterol Hepatol. 6: 79-96.[PMCID:in process]
-Featured as journal cover image.

Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng Z, Kaddis JS, Han A, Roelf K, Calderon RI, Hu X, Wilhelmy J, Grimes S, Corney D, Boutet S, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy M, Jain R, Cartwright CA, Niland JC, Hong Y, Carrington J, Breault D, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, and Kuo CJ. Injury-inducible stem cell potential of the intestinal enterendocrine lineage. (2017) Cell Stem Cell. 21:78-90. [PMCID:PMC5642297]

Silk AD, Gast CE, Davies PS, Fakhari FD, Vanderbeek GE, Mori M, and Wong MH. (2013) Fusion between hematopoietic and epithelial cells in adult human intestine. PLoS One, 8:e55572. [PMCID: in progress]

Clayburgh DR, Gross ND, Proby C, Koide J, and Wong MH. (2013) Resistance to Epidermal Growth Factor Receptor Inhibition in Cutaneous Squamous Cell Carcinoma of the Head and Neck through upregulation of insulin-like growth factor 1 receptor signaling: Potetnial for dual inhibition as a therapeutic modality. Head and Neck. 35:86-93. [PMCID: in progress]

Hessman CJ, Bubbers EJ, Billingsley KG, Herzig DO and Wong MH. (2011) Loss of expression of the cancer stem cell marker aldehyde dehydrogenase1 correlates with advanced stage colorectal cancer. American Journal of Surgery. Am J of Surg. 203:649-53. [PMCID: in progress]

Powell AE, Davies PS, Anderson EA, Silk AD, Pelz C, Impey S and Wong MH. (2011) Fusion between Intestinal epithelial cells and Macrophages in a cancer context results in nuclear reprogramming. Cancer Research, 71:1497-1505. [PMCID: PMC3079548]

Levin TG, Powell AE, Davies PS, Silk AD, Dismuke AD, Anderson EC, Swain JR, and Wong MH. (2010) Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. Gastroenterology, 139:2072-2082. [PMCID: PMC2997177]

Davies PS, Powell AE, and Wong MH. (2009) Inflammation and proliferation act together to mediate intestinal cell fusion. PLOS One, 4:e6530. [PMCID: PMC2716548]

Davies PS, Dismuke, AD, Powell AE, Carroll KH, and Wong MH. Wnt signaling expression pattern in the mouse intestine during homeostasis. (2008) BMC Gastroenterol, 8:57. [PMCID: PMC journal in process]

Bailey AS, Willenbring, H, Jiang S, Anderson DA, Schroeder DA, Wong MH, Grompe M and Fleming WH. Myeloid lineage progenitors give rise to vascular endothelial cells. (2006) Proc. Natl. Acad. Sci. USA, 103:13156-61. [PMCID: PMC1559769]

Rizvi AZ, Swain JS, Bailey AS, Davies PS, Decker AD, Willenbring H, Grompe M, Fleming WH, and Wong MH. (2006) Bone marrow-derived cells fuse with normal and transformed intestinal progenitor cells, Proc. Natl. Acad. Sci. USA,103:6321-5. [PMCID: PMC1535365]

Bailey, AS, Jiang, S, Afentoulis, M, Baumann, CI, Schroeder, DA, Olson, SB, Wong, MH, and Fleming, WH. (2004) Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells. Blood. 103:13-19.

Wong, MH, Huelsken, J, Birchmeier, W, and Gordon JI. (2002) Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling. J. Biol. Chem. 277:15843-15850.

Hooper, LV, Wong, MH, Thelin, A, Falk, PG, and Gordon, JI. (2001) Molecular analysis of commensal host- microbial relationships in the intestine. Science, 291:881-884.

Wong MH, Saam JR, Stappenbeck TS, Rexer CH, and Gordon JI. (2000) Genetic mosaic analysis based on Cre recombinase and navigated laser capture microdissection. Proc. Natl. Acad. Sci. USA, 97: 12601- 12606.

Wong MH, Rubinfeld, B and Gordon JI (1998) Effects of Forced Expression of an NH2-terminal Truncated β- Catenin on Mouse Intestinal Epithelial Homeostasis. J. Cell Biol. 141:765-777.

*Hermiston ML, *Wong, MH, and JI Gordon. (1995) Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system. Genes Dev. 10:985-996. (*equal contribution)